ChemicalBook > CAS DataBase List > FMOC-HIS-OH

FMOC-HIS-OH

Product Name
FMOC-HIS-OH
CAS No.
116611-64-4
Chemical Name
FMOC-HIS-OH
Synonyms
Fmoc-His;FMOC-HIS-OH;Fmoc-L-His-OH;FMOC-HISTIDINE;FMOC-L-HISTIDINE;Nα-Fmoc-L-histidine;N-a-Fmoc-L-histidine;N-α-Fmoc-L-histidine;FMOC-HIS-OH USP/EP/BP;Nα-Fmoc-L-histidine99%
CBNumber
CB8687841
Molecular Formula
C21H19N3O4
Formula Weight
377.39
MOL File
116611-64-4.mol
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FMOC-HIS-OH Property

Melting point:
171-174 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point:
706.7±60.0 °C(Predicted)
Density 
1.372±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO (Slightly), DMF (Slightly, Sonicated), Methanol (Very Slightly, Heated)
form 
Solid
pka
3.26±0.10(Predicted)
color 
White
InChI
InChI=1S/C21H19N3O4/c25-20(26)19(9-13-10-22-12-23-13)24-21(27)28-11-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,10,12,18-19H,9,11H2,(H,22,23)(H,24,27)(H,25,26)/t19-/m0/s1
InChIKey
SIRPVCUJLVXZPW-IBGZPJMESA-N
SMILES
C(O)(=O)[C@H](CC1N=CNC=1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
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Safety

HS Code 
29332900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H66407
Product name
Nalpha-Fmoc-L-histidine, 98%
Packaging
5g
Price
$80
Updated
2021/12/16
Alfa Aesar
Product number
H66407
Product name
Nalpha-Fmoc-L-histidine, 98%
Packaging
25g
Price
$320
Updated
2021/12/16
TRC
Product number
F633000
Product name
Nα-Fmoc-L-histidine
Packaging
5g
Price
$330
Updated
2021/12/16
Usbiological
Product number
277236
Product name
N-alpha-Fmoc-L-histidine
Packaging
2g
Price
$333
Updated
2021/12/16
Chem-Impex
Product number
05721
Product name
Nα-Fmoc-L-histidine,98%(HPLC)
Purity
98%(HPLC)
Packaging
25G
Price
$394.24
Updated
2021/12/16
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FMOC-HIS-OH Chemical Properties,Usage,Production

Description

Nα-Fmoc-L-histidine (FMOC-HIS-OH) holds great significance as a synthetic amino acid extensively employed in peptide synthesis. Its versatility makes it a highly sought-after reagent, widely used in various synthetic processes to create peptides, proteins, and even small molecules. Moreover, it catalyzes peptide and protein synthesis, further enhancing its utility. It is pivotal in unravelling biological processes such as enzymatic catalysis, protein structure, and drug design. Notably, this remarkable amino acid aids in understanding cell signalling pathways, which bear paramount importance in comprehending the mechanisms underlying diseases. The mechanism of action for Nα-Fmoc-L-histidine revolves around its ability to form essential peptide bonds. These bonds arise through a reaction with specific reagents, like DCC, leading to the creation of peptides. Subsequently, deprotection of the peptide bond occurs with the addition of a base, such as sodium hydroxide, followed by an acid, like trifluoroacetic acid.

Uses

Nα-Fmoc-L-histidine is an N-Fmoc-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.

FMOC-HIS-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-HIS-OH Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
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View Lastest Price from FMOC-HIS-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-His-OH 116611-64-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-12-13
Career Henan Chemical Co
Product
FMOC-HIS-OH 116611-64-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,100kg
Release date
2019-07-04

116611-64-4, FMOC-HIS-OHRelated Search:


  • FMOC-L-HISTIDINE
  • FMOC-HIS-OH
  • FMOC-HISTIDINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-HISTIDINE
  • N-α-Fmoc-L-histidine
  • N-a-Fmoc-L-histidine
  • N-.ALPHA.-FMOC -L-HISTIDINE
  • Fmoc-L-His-OH
  • Nα-(9H-Fluorene-9-ylmethoxycarbonyl)-L-histidine
  • (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1H-imidazol-4-yl)propanoic acid
  • (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine
  • Fmoc-His
  • N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-L-histidine
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl His-OH
  • Nα-Fmoc-L-histidine99%
  • (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-imidazol-5-yl)propanoic acid
  • N^a-Fmoc-L-histidine,98%
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol-5-yl)propanoicaci
  • FMOC-HIS-OH USP/EP/BP
  • Nα-Fmoc-L-histidine
  • FMOC-L-Histidine extrapure, 98%
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid|||(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine|||FMOC-L-Histidine
  • 116611-64-4
  • 3116611-64-4