FMOC-HIS-OH
- Product Name
- FMOC-HIS-OH
- CAS No.
- 116611-64-4
- Chemical Name
- FMOC-HIS-OH
- Synonyms
- Fmoc-His;FMOC-HIS-OH;Fmoc-L-His-OH;FMOC-HISTIDINE;FMOC-L-HISTIDINE;Nα-Fmoc-L-histidine;N-a-Fmoc-L-histidine;N-α-Fmoc-L-histidine;FMOC-HIS-OH USP/EP/BP;Nα-Fmoc-L-histidine99%
- CBNumber
- CB8687841
- Molecular Formula
- C21H19N3O4
- Formula Weight
- 377.39
- MOL File
- 116611-64-4.mol
FMOC-HIS-OH Property
- Melting point:
- 171-174 °C(Solv: methanol (67-56-1); water (7732-18-5))
- Boiling point:
- 706.7±60.0 °C(Predicted)
- Density
- 1.372±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO (Slightly), DMF (Slightly, Sonicated), Methanol (Very Slightly, Heated)
- form
- Solid
- pka
- 3.26±0.10(Predicted)
- color
- White
- InChI
- InChI=1S/C21H19N3O4/c25-20(26)19(9-13-10-22-12-23-13)24-21(27)28-11-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,10,12,18-19H,9,11H2,(H,22,23)(H,24,27)(H,25,26)/t19-/m0/s1
- InChIKey
- SIRPVCUJLVXZPW-IBGZPJMESA-N
- SMILES
- C(O)(=O)[C@H](CC1N=CNC=1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
Safety
- HS Code
- 29332900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H66407
- Product name
- Nalpha-Fmoc-L-histidine, 98%
- Packaging
- 5g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- H66407
- Product name
- Nalpha-Fmoc-L-histidine, 98%
- Packaging
- 25g
- Price
- $320
- Updated
- 2021/12/16
- Product number
- F633000
- Product name
- Nα-Fmoc-L-histidine
- Packaging
- 5g
- Price
- $330
- Updated
- 2021/12/16
- Product number
- 277236
- Product name
- N-alpha-Fmoc-L-histidine
- Packaging
- 2g
- Price
- $333
- Updated
- 2021/12/16
- Product number
- 05721
- Product name
- Nα-Fmoc-L-histidine,98%(HPLC)
- Purity
- 98%(HPLC)
- Packaging
- 25G
- Price
- $394.24
- Updated
- 2021/12/16
FMOC-HIS-OH Chemical Properties,Usage,Production
Description
Nα-Fmoc-L-histidine (FMOC-HIS-OH) holds great significance as a synthetic amino acid extensively employed in peptide synthesis. Its versatility makes it a highly sought-after reagent, widely used in various synthetic processes to create peptides, proteins, and even small molecules. Moreover, it catalyzes peptide and protein synthesis, further enhancing its utility. It is pivotal in unravelling biological processes such as enzymatic catalysis, protein structure, and drug design. Notably, this remarkable amino acid aids in understanding cell signalling pathways, which bear paramount importance in comprehending the mechanisms underlying diseases. The mechanism of action for Nα-Fmoc-L-histidine revolves around its ability to form essential peptide bonds. These bonds arise through a reaction with specific reagents, like DCC, leading to the creation of peptides. Subsequently, deprotection of the peptide bond occurs with the addition of a base, such as sodium hydroxide, followed by an acid, like trifluoroacetic acid.
Uses
Nα-Fmoc-L-histidine is an N-Fmoc-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.
FMOC-HIS-OH Preparation Products And Raw materials
Raw materials
Preparation Products
FMOC-HIS-OH Suppliers
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View Lastest Price from FMOC-HIS-OH manufacturers
- Product
- Fmoc-L-His-OH 116611-64-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T
- Release date
- 2023-12-13
- Product
- FMOC-HIS-OH 116611-64-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,100kg
- Release date
- 2019-07-04