ChemicalBook > CAS DataBase List > FMOC-HIS-OH

FMOC-HIS-OH

Product Name
FMOC-HIS-OH
CAS No.
116611-64-4
Chemical Name
FMOC-HIS-OH
Synonyms
Fmoc-His;FMOC-HIS-OH;Fmoc-L-His-OH;FMOC-HISTIDINE;FMOC-L-HISTIDINE;Nα-Fmoc-L-histidine;N-a-Fmoc-L-histidine;N-α-Fmoc-L-histidine;FMOC-HIS-OH USP/EP/BP;Nα-Fmoc-L-histidine99%
CBNumber
CB8687841
Molecular Formula
C21H19N3O4
Formula Weight
377.39
MOL File
116611-64-4.mol
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FMOC-HIS-OH Property

Melting point:
171-174 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point:
706.7±60.0 °C(Predicted)
Density 
1.372±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO (Slightly), DMF (Slightly, Sonicated), Methanol (Very Slightly, Heated)
form 
Solid
pka
3.26±0.10(Predicted)
color 
White
InChI
InChI=1S/C21H19N3O4/c25-20(26)19(9-13-10-22-12-23-13)24-21(27)28-11-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,10,12,18-19H,9,11H2,(H,22,23)(H,24,27)(H,25,26)/t19-/m0/s1
InChIKey
SIRPVCUJLVXZPW-IBGZPJMESA-N
SMILES
C(O)(=O)[C@H](CC1N=CNC=1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
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Safety

HS Code 
29332900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H66407
Product name
Nalpha-Fmoc-L-histidine, 98%
Packaging
5g
Price
$80
Updated
2021/12/16
Alfa Aesar
Product number
H66407
Product name
Nalpha-Fmoc-L-histidine, 98%
Packaging
25g
Price
$320
Updated
2021/12/16
TRC
Product number
F633000
Product name
Nα-Fmoc-L-histidine
Packaging
5g
Price
$330
Updated
2021/12/16
Usbiological
Product number
277236
Product name
N-alpha-Fmoc-L-histidine
Packaging
2g
Price
$333
Updated
2021/12/16
Chem-Impex
Product number
05721
Product name
Nα-Fmoc-L-histidine,98%(HPLC)
Purity
98%(HPLC)
Packaging
1G
Price
$23.18
Updated
2021/12/16
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FMOC-HIS-OH Chemical Properties,Usage,Production

Description

Nα-Fmoc-L-histidine (FMOC-HIS-OH) holds great significance as a synthetic amino acid extensively employed in peptide synthesis. Its versatility makes it a highly sought-after reagent, widely used in various synthetic processes to create peptides, proteins, and even small molecules. Moreover, it catalyzes peptide and protein synthesis, further enhancing its utility. It is pivotal in unravelling biological processes such as enzymatic catalysis, protein structure, and drug design. Notably, this remarkable amino acid aids in understanding cell signalling pathways, which bear paramount importance in comprehending the mechanisms underlying diseases. The mechanism of action for Nα-Fmoc-L-histidine revolves around its ability to form essential peptide bonds. These bonds arise through a reaction with specific reagents, like DCC, leading to the creation of peptides. Subsequently, deprotection of the peptide bond occurs with the addition of a base, such as sodium hydroxide, followed by an acid, like trifluoroacetic acid.

Uses

Nα-Fmoc-L-histidine is an N-Fmoc-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.

FMOC-HIS-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-HIS-OH Suppliers

China 106 Europe 1 Germany 2 India 3 Japan 2 Switzerland 1 United States 12 Global 127
J & K SCIENTIFIC LTD.
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View Lastest Price from FMOC-HIS-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-His-OH 116611-64-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-12-13
Career Henan Chemical Co
Product
FMOC-HIS-OH 116611-64-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,100kg
Release date
2019-07-04

116611-64-4, FMOC-HIS-OHRelated Search:

L-Lysine, N6-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]- FMOC-ARG(Z)2-OH FMOC-HIS(TOS)-OH N,N'-Bis(9-fluorenylmethyloxycarbonyl)-L-histidine N-Fmoc-N'-Trityl-L-histidine pentafluorophenyl ester FMOC-HIS(BOC)-OH FMOC-HIS-OH N-FMOC-3-(triphenylmethyl)-L-histidine Fmoc-His(Trt)-OH FMOC-HIS(3-BOM)-OH FMOC-THR-OH H2O,FMOC-THR-OH MONOHYDRATE,FMOC-THR-OH FMOC-D-HIS-OH FMOC-NLE-OH FMOC-PRA-OH 1-BOC-4-FMOC-PIP-OH FMOC-PIP-OH FMOC-TPI-OH FMOC-THI-OH

  • FMOC-L-HISTIDINE
  • FMOC-HIS-OH
  • FMOC-HISTIDINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-HISTIDINE
  • N-α-Fmoc-L-histidine
  • N-a-Fmoc-L-histidine
  • N-.ALPHA.-FMOC -L-HISTIDINE
  • Fmoc-L-His-OH
  • Nα-(9H-Fluorene-9-ylmethoxycarbonyl)-L-histidine
  • (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1H-imidazol-4-yl)propanoic acid
  • (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine
  • Fmoc-His
  • N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-L-histidine
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl His-OH
  • Nα-Fmoc-L-histidine99%
  • (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-imidazol-5-yl)propanoic acid
  • N^a-Fmoc-L-histidine,98%
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol-5-yl)propanoicaci
  • FMOC-HIS-OH USP/EP/BP
  • Nα-Fmoc-L-histidine
  • FMOC-L-Histidine extrapure, 98%
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid|||(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine|||FMOC-L-Histidine
  • 116611-64-4
  • 3116611-64-4