6-CHLORO-2-CYANO-3-NITROPYRIDINE
- Product Name
- 6-CHLORO-2-CYANO-3-NITROPYRIDINE
- CAS No.
- 93683-65-9
- Chemical Name
- 6-CHLORO-2-CYANO-3-NITROPYRIDINE
- Synonyms
- 6-Chloro-3-nitropicolinonitrile;C90144;6-Chloro-2-cyano-3-nitropyidine;6-CHLORO-2-CYANO-3-NITROPYRIDIN;6-CHLORO-2-CYANO-3-NITROPYRIDINE;2-cyano-6-chloro-3-nitropyridine;6-chloro-3-nitro-2-pyridinecarbonitrile;6-CHLORO-3-NITROPYRIDINE-2-CARBONITRILE;2-Pyridinecarbonitrile, 6-chloro-3-nitro-;6-Chloro-3-nitro-2-cyanopyridine≥ 97.0% (HPLC)
- CBNumber
- CB8689052
- Molecular Formula
- C6H2ClN3O2
- Formula Weight
- 183.55
- MOL File
- 93683-65-9.mol
6-CHLORO-2-CYANO-3-NITROPYRIDINE Property
- Melting point:
- 118-120 °C
- Boiling point:
- 347.2±42.0 °C(Predicted)
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- -10.14±0.10(Predicted)
- Appearance
- White to light yellow Solid
- InChI
- InChI=1S/C6H2ClN3O2/c7-6-2-1-5(10(11)12)4(3-8)9-6/h1-2H
- InChIKey
- XVIHGTRTKQZJAC-UHFFFAOYSA-N
- SMILES
- C1(C#N)=NC(Cl)=CC=C1[N+]([O-])=O
- CAS DataBase Reference
- 93683-65-9(CAS DataBase Reference)
Safety
- Hazard Codes
- T
- RIDADR
- UN2811
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OR6409
- Product name
- 6-Chloro-3-nitropyridine-2-carbonitrile
- Purity
- 98%
- Packaging
- 1g
- Price
- $21
- Updated
- 2021/12/16
- Product number
- 4H55-5-X2
- Product name
- 6-Chloro-3-nitropyridine-2-carbonitrile
- Purity
- 98%
- Packaging
- 1g
- Price
- $23
- Updated
- 2021/12/16
- Product number
- X8410
- Product name
- 6-Chloro-2-cyano-3-nitropyridine
- Packaging
- 1g
- Price
- $54
- Updated
- 2021/12/16
- Product number
- FC06230
- Product name
- 6-Chloro-2-cyano-3-nitropyridine
- Packaging
- 2g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CS-0022422
- Product name
- 6-Chloro-3-nitropicolinonitrile
- Purity
- 98.85%
- Packaging
- 5g
- Price
- $69
- Updated
- 2021/12/16
6-CHLORO-2-CYANO-3-NITROPYRIDINE Chemical Properties,Usage,Production
Chemical Properties
Light yellow Cryst
Synthesis
16013-85-7
544-92-3
93683-65-9
General procedure for the preparation of 2-cyano-3-nitro-6-chloropyridine: 1. 2,6-dichloro-3-nitropyridine (5.0 g, 25.9 mmol) and cuprous(I) cyanide (2.55 g, 28.5 mmol) were mixed in N-methylpyrrolidone (19 mL). 2. the mixture was heated to 180 °C and maintained for 15 min. 3. After completion of the reaction, cooled to room temperature, the reaction mixture was poured into ice water and stirred for 10 minutes. 4. The aqueous layer was separated and the organic layer was extracted with boiling toluene followed by re-extraction with ethyl acetate. 5. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. 6. The residue was ground with ether and filtered to give 2-cyano-3-nitro-6-chloropyridine (1.76 g, 39% yield). 1H-NMR (CDCl3, 300MHz) data: δ 7.78 (d, J = 8.9Hz, 1H), 8.54 (d, J = 8.9Hz, 1H).
References
[1] Journal of Heterocyclic Chemistry, 1984, vol. 21, # 5, p. 1521 - 1525
[2] Patent: WO2005/97805, 2005, A1. Location in patent: Page/Page column 48-49
[3] Journal of Medicinal Chemistry, 1998, vol. 41, # 23, p. 4533 - 4541
6-CHLORO-2-CYANO-3-NITROPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-CHLORO-2-CYANO-3-NITROPYRIDINE manufacturers
- Product
- 6-CHLORO-2-CYANO-3-NITROPYRIDINE 93683-65-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-12
- Product
- 6-CHLORO-2-CYANO-3-NITROPYRIDINE 93683-65-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-11