2-Chloro-5-hydroxypyridine

Uses

Product Name: 2-Chloro-5-hydroxypyridine
CAS No.: 41288-96-4
Chemical Name: 2-Chloro-5-hydroxypyridine
Synonyms: 6-CHLOROPYRIDIN-3-OL;2-Chloro-5-Pyridol;6-Chloro-3-pyridinol;2-CHLORO-5-PYRIDINOL;2-Chloropyridin-5-ol;6-chloropyridine-3-ol;3-PYRIDINOL, 6-CHLORO-;2-Chloro-5-hydropyridine;2-CHLORO-5-HYDROXYPYRIDINE;3-Pyridinol,6-chloro-(9CI)
CBNumber: CB8695961
Molecular Formula: C5H4ClNO
Formula Weight: 129.54
MOL File: 41288-96-4.mol

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2-Chloro-5-hydroxypyridine Property

Melting point:: 155-158°C
Boiling point:: 351.9±22.0 °C(Predicted)
Density: 1.392±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: 8.69±0.10(Predicted)
color: Light yellow to Brown
InChI: InChI=1S/C5H4ClNO/c6-5-2-1-4(8)3-7-5/h1-3,8H
InChIKey: KVCOOWROABTXDJ-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=CC=C1O
CAS DataBase Reference: 41288-96-4(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39-36-37
HazardClass: IRRITANT
PackingGroup: III
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2271
Product name: 2-Chloro-5-hydroxypyridine
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $165
Updated: 2025/07/31

TRC

Product number: C381313
Product name: 2-Chloro-5-hydroxypyridine
Packaging: 500mg
Price: $60
Updated: 2021/12/16

TRC

Product number: C381313
Product name: 2-Chloro-5-hydroxypyridine
Packaging: 2.5g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: D539
Product name: 2-Chloro-5-Hydroxypyridine
Packaging: 1g
Price: $14
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: Y15333
Product name: 2-Chloro-5-hydroxypyridine
Purity: 98%
Packaging: 5g
Price: $15
Updated: 2021/12/16

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2-Chloro-5-hydroxypyridine Chemical Properties,Usage,Production

Uses

2-Chloro-5-hydroxypyridine is an organic intermediate.

Chemical Properties

Light yellow Cryst

Synthesis

188057-24-1

41288-96-4

11B. 6-Chloropyridin-3-yl acetate (11.1 g, 64.7 mmol) from step 11a was dissolved in methanol at room temperature, followed by addition of solid potassium carbonate (4.47 g, 32.4 mmol). The reaction mixture was stirred for 2 hours and the volatiles were removed under reduced pressure. The residue was diluted with ether and water, and the aqueous phase was neutralized to pH 7 by addition of aqueous 1 N hydrochloric acid.The organic and aqueous layers were separated and the aqueous phase was extracted twice with ether. The organic extracts were combined, dried over magnesium sulfate and concentrated to give 2-chloro-5-hydroxypyridine as a white solid (8.03 g, 96% yield): melting point 155 °C; 1H NMR (CD3OD, 300 MHz) δ 7.20-7.28 (m, 2H), 7.88 (m, 1H); mass spectrum (CI/NH3) m/z: 130,132 (M+H) +; 147,149 (M+NH4)+.

References

[1] Patent: US6696439, 2004, B1. Location in patent: Page column 20
[2] Patent: US6001849, 1999, A
[3] Tetrahedron Letters, 2003, vol. 44, # 4, p. 725 - 728
[4] Patent: EP1698626, 2006, A1. Location in patent: Page/Page column 24
[5] Patent: WO2004/72072, 2004, A1. Location in patent: Page 85

2-Chloro-5-hydroxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-5-hydroxypyridine Suppliers

Americas 1 Austria 1 China 326 Europe 4 France 1 Germany 5 India 18 Japan 3 Jordan 1 The Netherlands 1 Ukraine 1 United Kingdom 11 United States 47 Global 420

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

CHEMSTEP

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ecochem international chemical broker

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kemikalieimport

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ProdList: 6685
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View Lastest Price from 2-Chloro-5-hydroxypyridine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Chloro-5-hydroxypyridine 41288-96-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-08

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Chloro-5-hydroxypyridine 41288-96-4
Price: US $8.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-13

Dideu Industries Group Limited

Product: 2-Chloro-5-hydroxypyridine 41288-96-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-09-24

41288-96-4, 2-Chloro-5-hydroxypyridineRelated Search:

2-Chloro-5-fluoropyridine 2,6-Lutidine Clopidol 2-Chloro-5-chloromethylpyridine 3-Hydroxypyridine Chromium picolinate 2-Chloro-3-cyanopyridine Pentachloropyridine Chrysin 5-Amino-2-chloropyridine 2-chloro-5-cyanopyridine 3-Bromo-6-chloro-2-methylpyridine 5-Bromo-2-chloropyridine 6-Chloro-2-methyl-3-nitropyridine 2-CHLORO-5-METHOXYPYRIDINE 2-Chloro-5-nitropyridine 2-Chloro-5-iodopyridine 5-Bromo-2-chlorobenzoic acid

6-CHLOROPYRIDIN-3-OL

6-Chloro-3-pyridinol

3-PYRIDINOL, 6-CHLORO-

2-CHLORO-5-HYDROXYPYRIDINE

2-CHLORO-5-PYRIDINOL

2-Chloro-5-Pyridol

2-Chloropyridin-5-ol

3-Pyridinol,6-chloro-(9CI)

2-CHLORO-5-HYDROXYPYRIDINE 98%

2-CHLORO-5-HYDROXYPYRIDINE 99+%

2-Chloro-5-hydropyridine

6-chloropyridine-3-ol

2-Chloro-5-hydroxypyridine 98+%

2-Chloropyridin-5-ol, 6-Chloropyridin-3-ol

2-Chloro-5-hydroxypyridine≥ 99% (HPLC)

2-Chloro-5-hydroxypyridine(RS20004430)

2-Chloro-5-hydroxypyridine&gt

2-Chloro-5-hydroxypyridine ISO 9001：2015 REACH

41288-96-4

Building Blocks

Pyridines

Heterocyclic Building Blocks

Halogenated Heterocycles

Boronic Acid

Halides

Pyridines

Pyridines derivates

PYRIDINE

pyridine derivative

Pyridine Series