2-Chloro-5-hydroxypyridine
Uses- Product Name
- 2-Chloro-5-hydroxypyridine
- CAS No.
- 41288-96-4
- Chemical Name
- 2-Chloro-5-hydroxypyridine
- Synonyms
- 6-CHLOROPYRIDIN-3-OL;2-Chloro-5-Pyridol;6-Chloro-3-pyridinol;2-CHLORO-5-PYRIDINOL;2-Chloropyridin-5-ol;6-chloropyridine-3-ol;3-PYRIDINOL, 6-CHLORO-;2-Chloro-5-hydropyridine;2-CHLORO-5-HYDROXYPYRIDINE;3-Pyridinol,6-chloro-(9CI)
- CBNumber
- CB8695961
- Molecular Formula
- C5H4ClNO
- Formula Weight
- 129.54
- MOL File
- 41288-96-4.mol
2-Chloro-5-hydroxypyridine Property
- Melting point:
- 155-158°C
- Boiling point:
- 351.9±22.0 °C(Predicted)
- Density
- 1.392±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- 8.69±0.10(Predicted)
- color
- Light yellow to Brown
- InChI
- InChI=1S/C5H4ClNO/c6-5-2-1-4(8)3-7-5/h1-3,8H
- InChIKey
- KVCOOWROABTXDJ-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=CC=C1O
- CAS DataBase Reference
- 41288-96-4(CAS DataBase Reference)
Safety
- Hazard Codes
- T,Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39-36-37
- HazardClass
- IRRITANT
- PackingGroup
- III
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C2271
- Product name
- 2-Chloro-5-hydroxypyridine
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $165
- Updated
- 2025/07/31
- Product number
- C381313
- Product name
- 2-Chloro-5-hydroxypyridine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- C381313
- Product name
- 2-Chloro-5-hydroxypyridine
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- D539
- Product name
- 2-Chloro-5-Hydroxypyridine
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- Y15333
- Product name
- 2-Chloro-5-hydroxypyridine
- Purity
- 98%
- Packaging
- 5g
- Price
- $15
- Updated
- 2021/12/16
2-Chloro-5-hydroxypyridine Chemical Properties,Usage,Production
Uses
2-Chloro-5-hydroxypyridine is an organic intermediate.
Chemical Properties
Light yellow Cryst
Synthesis
188057-24-1
41288-96-4
11B. 6-Chloropyridin-3-yl acetate (11.1 g, 64.7 mmol) from step 11a was dissolved in methanol at room temperature, followed by addition of solid potassium carbonate (4.47 g, 32.4 mmol). The reaction mixture was stirred for 2 hours and the volatiles were removed under reduced pressure. The residue was diluted with ether and water, and the aqueous phase was neutralized to pH 7 by addition of aqueous 1 N hydrochloric acid.The organic and aqueous layers were separated and the aqueous phase was extracted twice with ether. The organic extracts were combined, dried over magnesium sulfate and concentrated to give 2-chloro-5-hydroxypyridine as a white solid (8.03 g, 96% yield): melting point 155 °C; 1H NMR (CD3OD, 300 MHz) δ 7.20-7.28 (m, 2H), 7.88 (m, 1H); mass spectrum (CI/NH3) m/z: 130,132 (M+H) +; 147,149 (M+NH4)+.
References
[1] Patent: US6696439, 2004, B1. Location in patent: Page column 20
[2] Patent: US6001849, 1999, A
[3] Tetrahedron Letters, 2003, vol. 44, # 4, p. 725 - 728
[4] Patent: EP1698626, 2006, A1. Location in patent: Page/Page column 24
[5] Patent: WO2004/72072, 2004, A1. Location in patent: Page 85
2-Chloro-5-hydroxypyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-5-hydroxypyridine Suppliers
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View Lastest Price from 2-Chloro-5-hydroxypyridine manufacturers
- Product
- 2-Chloro-5-hydroxypyridine 41288-96-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-08
- Product
- 2-Chloro-5-hydroxypyridine 41288-96-4
- Price
- US $8.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2025-03-13
- Product
- 2-Chloro-5-hydroxypyridine 41288-96-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-24