Ethyl N-piperazinecarboxylate
- Product Name
- Ethyl N-piperazinecarboxylate
- CAS No.
- 120-43-4
- Chemical Name
- Ethyl N-piperazinecarboxylate
- Synonyms
- ETHYL PIPERAZINE-1-CARBOXYLATE;1-CARBETHOXYPIPERAZINE;AKOS BC-0597;RARECHEM AH CK 0098;TIMTEC-BB SBB003993;LABOTEST-BB LT00138086;N-CARBETHOXYPIPERAZINE;ethylcarbonylpiperazine;1-CARBOETHOXYPIPERAZINE;Ethylcarbonyl piperazine
- CBNumber
- CB8698856
- Molecular Formula
- C7H14N2O2
- Formula Weight
- 158.2
- MOL File
- 120-43-4.mol
Ethyl N-piperazinecarboxylate Property
- Melting point:
- 120 °C
- Boiling point:
- 273 °C (lit.)
- Density
- 1.08 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.477(lit.)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Oily Liquid
- pka
- 8.50±0.10(Predicted)
- color
- Clear light yellow
- Water Solubility
- soluble
- BRN
- 125780
- CAS DataBase Reference
- 120-43-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 1-Piperazinecarboxylic acid, ethyl ester(120-43-4)
- EPA Substance Registry System
- 1-Piperazinecarboxylic acid, ethyl ester (120-43-4)
Safety
- Hazard Codes
- Xn,T
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 23-24/25-37/39-26-36
- RIDADR
- UN 2810 6.1/PG 3
- WGK Germany
- 3
- RTECS
- TL1378000
- Hazard Note
- Toxic
- TSCA
- Yes
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29335995
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- E45600
- Product name
- Ethyl 1-piperazinecarboxylate
- Purity
- 99%
- Packaging
- 25g
- Price
- $62.6
- Updated
- 2025/07/31
- Product number
- E45600
- Product name
- Ethyl 1-piperazinecarboxylate
- Purity
- 99%
- Packaging
- 100g
- Price
- $135
- Updated
- 2023/01/07
- Product number
- P1349
- Product name
- Ethyl 1-Piperazinecarboxylate
- Purity
- >96.0%(GC)
- Packaging
- 25g
- Price
- $28
- Updated
- 2025/07/31
- Product number
- P1349
- Product name
- Ethyl 1-Piperazinecarboxylate
- Purity
- >96.0%(GC)
- Packaging
- 500g
- Price
- $282
- Updated
- 2021/12/16
- Product number
- E922500
- Product name
- Ethyl 1-Piperazinecarboxylate
- Packaging
- 5g
- Price
- $70
- Updated
- 2021/12/16
Ethyl N-piperazinecarboxylate Chemical Properties,Usage,Production
Chemical Properties
clear light yellow oily liquid
Uses
Intermediate.
Synthesis
110-85-0
541-41-3
120-43-4
Piperazine (2 g, 23.2 mmol) and deionized water (10 mL) were added to a reaction flask and stirred at 25 °C until completely dissolved, then cooled to 0 °C. A methanol solution (20 mL) of ethyl chloroformate (1.26 g, 11.6 mmol) was slowly added dropwise with stirring. After the dropwise addition was completed, the reaction system was warmed to 25 °C and stirring was continued for 4 hours. Upon completion of the reaction, saturated aqueous sodium chloride solution (30 mL) and dichloromethane (200 mL) were added to the reaction solution for extraction and separation. The organic layer was collected and dried with anhydrous sodium sulfate. The organic solvent was removed by distillation under reduced pressure, and the resulting crude product was purified by column chromatography (eluent: dichloromethane/methanol, 40:1, v/v/v/v) to give ethyl N-piperazinecarboxylate (0.62 g, 33.7% yield) as a white solid.
References
[1] Patent: CN103664899, 2017, B. Location in patent: Paragraph 0465-0469
[2] Patent: CN103664925, 2018, B. Location in patent: Paragraph 0458; 0461; 0462
[3] Journal of the Chemical Society, 1929, p. 50
[4] Journal of Organic Chemistry, 1948, vol. 13, p. 134,138
[5] Chemische Berichte, 1933, vol. 66, p. 113,116
Ethyl N-piperazinecarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl N-piperazinecarboxylate manufacturers
- Product
- Ethyl N-piperazinecarboxylate 120-43-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-08
- Product
- Ethyl N-piperazinecarboxylate 120-43-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-08
- Product
- Ethyl N-piperazinecarboxylate 120-43-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons
- Release date
- 2022-02-23