N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
- Product Name
- N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
- CAS No.
- 252720-31-3
- Chemical Name
- N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
- Synonyms
- 2-Pyridinamine,6-(methylsulfonyl)-;4-(Boc-aMino)piperidine-4-carboxylic Acid;4-(N-Boc-amino)piperidine-4-carboxylic acid;N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID;N-BOC-amino-piperidinyl-1,1-dicarboxylicacid;N-BOC-Amino-piperidinyl-1,1-carboxylic acid,95%;4-(tert-butoxycarbonyl)piperidine-4-carboxylic acid;4-(Boc-amino)piperidine-4-carboxylic acid - [A14679];4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-ca;2-{[(tert-butoxy)carbonyl]aMino}piperidine-1-carboxylic acid
- CBNumber
- CB8716206
- Molecular Formula
- C11H20N2O4
- Formula Weight
- 244.29
- MOL File
- 252720-31-3.mol
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Property
- Boiling point:
- 410℃
- Density
- 1.18
- refractive index
- 1.4620 (estimate)
- Flash point:
- 202℃
- storage temp.
- 2-8°C(protect from light)
- pka
- 3.36±0.20(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C11H20N2O4/c1-10(2,3)17-9(16)13-11(8(14)15)4-6-12-7-5-11/h12H,4-7H2,1-3H3,(H,13,16)(H,14,15)
- InChIKey
- RAENIWWUAIMXSI-UHFFFAOYSA-N
- SMILES
- N1CCC(NC(OC(C)(C)C)=O)(C(O)=O)CC1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 125230
- Product name
- 4-(Boc-amino)piperidine-4-carboxylicacid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $826
- Updated
- 2021/12/16
- Product number
- 2018AB
- Product name
- 4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylicacid
- Packaging
- 5g
- Price
- $918
- Updated
- 2021/12/16
- Product number
- A14679
- Product name
- 4-(Boc-amino)piperidine-4-carboxylicacid
- Purity
- 95+%
- Packaging
- 10g
- Price
- $2190
- Updated
- 2021/12/16
- Product number
- A103006
- Product name
- 4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylicacid
- Purity
- 95%
- Packaging
- 25g
- Price
- $1708
- Updated
- 2021/12/16
- Product number
- A103006
- Product name
- 4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylicacid
- Purity
- 95%
- Packaging
- 10g
- Price
- $887
- Updated
- 2021/12/16
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Chemical Properties,Usage,Production
Chemical Properties
White to off-white crystalline powder
Uses
N-Boc-amino-piperidinyl-1,1-carboxylic acid is used in pharmaceutical synthesis.
Synthesis
The synthesis of N-BOC-amino-piperidinyl-1,1-carboxylic acid usually starts with piperidine-4-carboxylic acid. Sodium bicarbonate and di-tert-butyl dicarbonate (Boc₂O) are added to the reaction system, and the amino protection reaction is carried out in a solvent such as tetrahydrofuran (THF) or 1,4-dioxane. The reaction is stirred at room temperature for several hours until the reaction is completed. Subsequently, the crude product is obtained by steps such as ethyl acetate extraction, pH adjustment of the aqueous phase, drying of the organic phase and reduced pressure concentration, and then purified by column chromatography using a mixed solvent of ethyl acetate and n-hexane as an eluent to finally obtain a high-purity target compound.
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Suppliers
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View Lastest Price from N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID manufacturers
- Product
- N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID 252720-31-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-11-11
- Product
- 4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylic acid 252720-31-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1
- Release date
- 2025-08-28
- Product
- N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID 252720-31-3
- Price
- US $50.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-22