ChemicalBook > CAS DataBase List > N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID

N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID

Product Name
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
CAS No.
252720-31-3
Chemical Name
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
Synonyms
2-Pyridinamine,6-(methylsulfonyl)-;4-(Boc-aMino)piperidine-4-carboxylic Acid;4-(N-Boc-amino)piperidine-4-carboxylic acid;N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID;N-BOC-amino-piperidinyl-1,1-dicarboxylicacid;N-BOC-Amino-piperidinyl-1,1-carboxylic acid,95%;4-(tert-butoxycarbonyl)piperidine-4-carboxylic acid;4-(Boc-amino)piperidine-4-carboxylic acid - [A14679];4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-ca;2-{[(tert-butoxy)carbonyl]aMino}piperidine-1-carboxylic acid
CBNumber
CB8716206
Molecular Formula
C11H20N2O4
Formula Weight
244.29
MOL File
252720-31-3.mol
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N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Property

Boiling point:
410℃
Density 
1.18
refractive index 
1.4620 (estimate)
Flash point:
202℃
storage temp. 
2-8°C(protect from light)
pka
3.36±0.20(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C11H20N2O4/c1-10(2,3)17-9(16)13-11(8(14)15)4-6-12-7-5-11/h12H,4-7H2,1-3H3,(H,13,16)(H,14,15)
InChIKey
RAENIWWUAIMXSI-UHFFFAOYSA-N
SMILES
N1CCC(NC(OC(C)(C)C)=O)(C(O)=O)CC1
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
125230
Product name
4-(Boc-amino)piperidine-4-carboxylicacid
Purity
95+%
Packaging
1g
Price
$826
Updated
2021/12/16
AK Scientific
Product number
2018AB
Product name
4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylicacid
Packaging
5g
Price
$918
Updated
2021/12/16
Synthonix
Product number
A14679
Product name
4-(Boc-amino)piperidine-4-carboxylicacid
Purity
95+%
Packaging
10g
Price
$2190
Updated
2021/12/16
Ambeed
Product number
A103006
Product name
4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylicacid
Purity
95%
Packaging
25g
Price
$1708
Updated
2021/12/16
Ambeed
Product number
A103006
Product name
4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylicacid
Purity
95%
Packaging
10g
Price
$887
Updated
2021/12/16
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N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

White to off-white crystalline powder

Uses

N-Boc-amino-piperidinyl-1,1-carboxylic acid is used in pharmaceutical synthesis.

Synthesis

The synthesis of N-BOC-amino-piperidinyl-1,1-carboxylic acid usually starts with piperidine-4-carboxylic acid. Sodium bicarbonate and di-tert-butyl dicarbonate (Boc₂O) are added to the reaction system, and the amino protection reaction is carried out in a solvent such as tetrahydrofuran (THF) or 1,4-dioxane. The reaction is stirred at room temperature for several hours until the reaction is completed. Subsequently, the crude product is obtained by steps such as ethyl acetate extraction, pH adjustment of the aqueous phase, drying of the organic phase and reduced pressure concentration, and then purified by column chromatography using a mixed solvent of ethyl acetate and n-hexane as an eluent to finally obtain a high-purity target compound.

N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID Suppliers

Hangzhou Chemtrue Bio-Tech Co.,Ltd.
Tel
0571-86828652 18857119830
Fax
0571-83522824
Email
sales@chemtrue-bio.com
Country
China
ProdList
252
Advantage
58
SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD
Tel
0838-2809458 13350585791
Email
pharm@biots.cn
Country
China
ProdList
589
Advantage
58
Suzhou Chukai PharmaTech
Tel
0512-88812066
Fax
86-512-63926099
Email
wenlongfcb@qq.com
Country
China
ProdList
396
Advantage
58
Bayee Biotech (Anqing) Co., Ltd.
Tel
0556-5032306 18917961636
Email
wtx@bayeebio.com
Country
China
ProdList
239
Advantage
61
Shanghai Hope Chem Co., Ltd.,
Tel
+21-18501659228 18501659228
Fax
sales@hope-chem.com
Email
info@hope-chem.com
Country
China
ProdList
474
Advantage
55
Shanghai Jinsheng Pharmaceutical Co., Ltd.
Tel
1365-13651960330 13651960330
Email
xiangfeixia@jspharmatech.com
Country
China
ProdList
356
Advantage
58
Nanjing F&S Pharmatech Co., Ltd.
Tel
025-86950358 13390612682
Email
wangjinyu@fshpharm.com
Country
China
ProdList
170
Advantage
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Shanghai Xchemtech Co., Ltd.
Tel
17721086216
Email
25522996@qq.com
Country
China
ProdList
149
Advantage
58
JIANGXI HANHE PHARMACEUTICAL CO.,LTD
Tel
18721221949
Email
zhangle@jxhhzy.com
Country
China
ProdList
102
Advantage
58
Z IntellecChem& Tech. Co., Ltd
Tel
0511-15050866711; 15050866711
Fax
QQ:2677337387
Email
contact@zintellec.com
Country
China
ProdList
99
Advantage
62
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View Lastest Price from N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID 252720-31-3
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-11-11
Jinan Ruitong Biotech Co., Ltd.
Product
4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylic acid 252720-31-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-08-28
Henan Fengda Chemical Co., Ltd
Product
N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID 252720-31-3
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22

252720-31-3, N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACIDRelated Search:


  • N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
  • N-(TERT-BUTOXYCARBONYL)-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
  • N-BOC-Amino-piperidinyl-1,1-carboxylic acid,95%
  • 4-(tert-butoxycarbonyl)piperidine-4-carboxylic acid
  • 4-(Boc-aMino)piperidine-4-carboxylic Acid
  • 2-{[(tert-butoxy)carbonyl]aMino}piperidine-1-carboxylic acid
  • 4-[[(tert-butoxyl)carbonyl]amino]-4-piperidinecarboxylic acid
  • 4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-carboxylic acid
  • 4-Piperidinecarboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-
  • 4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidin-1-ium-4-carboxylate
  • 4-(N-Boc-amino)piperidine-4-carboxylic acid
  • 2-Pyridinamine,6-(methylsulfonyl)-
  • 4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-ca
  • 4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-carboxylicaci
  • N-BOC-amino-piperidinyl-1,1-dicarboxylicacid
  • 4-(Boc-amino)piperidine-4-carboxylic acid - [A14679]
  • 252720-31-3