Calcifediol Monohydrate

Product Name: Calcifediol Monohydrate
CAS No.: 63283-36-3
Chemical Name: Calcifediol Monohydrate
Synonyms: CALCIFEDIOL;25-HYDROXYVITAMIN D3;25-OH-D3;25-HYDROXYCHOLECALCIFEROL;25-OH-VD3;CALCIDIOL;25-OH-Vitamin D3;25-HYDROXYVITAMIN D3;25-HYDROXYCHOLECALCIFEROL;Calcifediol CRS;25-hydroxy VD3)
CBNumber: CB8727251
Molecular Formula: C27H46O3
Formula Weight: 418.66
MOL File: 63283-36-3.mol

More

Less

Calcifediol Monohydrate Property

Flash point:: 14℃
storage temp.: -20°C
solubility: Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in fatty oils.
form: Solid
color: White to Light yellow
BRN: 4270041
InChIKey: JWUBBDSIWDLEOM-LCDSLSDMSA-N
SMILES: C[C@]12CCC/C(=C\C=C3\C[C@@H](O)CCC\3=C)/[C@]1([H])CC[C@]2([H])[C@H](C)CCCC(O)(C)C.O |&1:1,10,16,20,22,r|
CAS DataBase Reference: 63283-36-3(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: T+
Risk Statements: 28-48/25-26-24/25
Safety Statements: 28-36/37-45
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
F: 8-10-19
HS Code: 29362900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2359
Product name: Calcifediol
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 100MG
Price: $739
Updated: 2024/03/01

Sigma-Aldrich

Product number: H-083
Product name: 25-Hydroxyvitamin D3 solution
Purity: 100?μg/mLinethanol,ampuleof1?mL,certifiedreferencematerial,Cerilliant?
Packaging: 1mL
Price: $165
Updated: 2024/03/01

Sigma-Aldrich

Product number: 17938
Product name: 25-Hydroxyvitamin D3 monohydrate
Purity: ≥99.0% (HPLC)
Packaging: 1mg
Price: $394
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1086108
Product name: Calcifediol
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 75mg
Price: $1150
Updated: 2024/03/01

TCI Chemical

Product number: C3537
Product name: Calcifediol Monohydrate
Purity: >98.0%(HPLC)
Packaging: 10mg
Price: $219
Updated: 2024/03/01

More

Less

Calcifediol Monohydrate Chemical Properties,Usage,Production

Description

Calcifediol monohydrate (25-hydroxyvitamin D3 monohydrate) is a potent VDR ligand and vitamin D supplement. Calcifediol is a precursor of the Vitamin D Endocrine System (VDES), which is hydroxylated in the liver to produce the active form of calcitriol. Calcifediol rapidly raises serum levels of Calcifediol rapidly increases serum levels of vitamin D.

Chemical Properties

White or almost white crystals.

Uses

Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It is produced in the liver and is the best indicator of the body’s vitamin D stores. It is effective in the treatment of ricket

Uses

25-Hydroxyvitamin D3 may be used as a certified reference material (CRM) for the determination of the analyte in biological samples by chromatography techniques.

Definition

ChEBI: Calcifediol monohydrate is a vitamin D.

brand name

Calderol (Organon).

General Description

A Certified Spiking Solution^? of 25-Hydroxyvitamin D3, a prohormone whose blood serum levels are used to determine Vitamin D nutritional status. This solution standard is suitable for critical quantitative applications in research and clinical environments including: for use in preparation of controls and calibrators for LC/UV and LC-MS/MS assays; as system tuning/suitability standards; linearity verification; internal proficiency testing; and for OEM use in preparation of reagents, development of assays and instrument IQ/OQ. The stable, quantitative solution format provides significant benefits to the user including material savings, increased efficiency of labor, and convenience of use. The shelf stable Snap-N-Spike^? format allows laboratories to eliminate painstaking weighing operations and provides the ability to spike a known concentration of analyte into their matrix of choice just before use.

Biochem/physiol Actions

Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol) is a synthetic analog that is metabolized to 1,25-dihydroxycholecalciferol, the biologically active form of vitamin D3. Other analogues of cholecalciferol result from different hydroxylations. 25-dihydroxycholecalciferol is a the major circulating form of vitamin D3 and a physiological precursor of 1α,25-Dihydroxycholecalciferol. The conversion is catalyzed by 25-Hydroxyvitamin D3 1-α-hydroxylase (VD3 1A hydroxylase) also known ascytochrome p450 27B1 (CYP27B1).

Side effects

Common side effects of Calcifediol Monohydrate include: constipation, runny or stuffy nose, sneezing, sore throat. Some patients may experience joint pain. Serious side effects may include: feeling tired, difficulty thinking, loss of appetite, nausea, vomiting, constipation, increased thirst, increased urination or weight loss, shortness of breath, pale skin, broken bones, and severe allergic reactions. If any of these serious adverse reactions occur, please seek medical attention immediately.

Safety

The European Chemicals Agency (ECHA)- external site hazard classification and labeling for calcifediol monohydrate is 'Danger! According to the classification provided by companies to ECHA in CLP notifications, this substance is fatal if swallowed, is fatal in contact with skin, is fatal if inhaled, causes damage to organs through prolonged or repeated exposure, is suspected of damaging fertility or the unborn child and may cause long lasting harmful effects to aquatic life'.

target

IL Receptor

Dosage

Calcidiol monohydrate contains the monohydrate form of the major circulating metabolite of vitamin D3 in the body and is a source of 1,25-dihydroxyvitamin D, the biologically active form of vitamin D. Calciferol monohydrate (25-hydroxycholecalciferol monohydrate) is safe under recommended conditions and level of use (up to 10 μg/day) and is safe for children >11 years of age and adults, including pregnant and lactating women.

Calcifediol Monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Calcifediol Monohydrate Suppliers

Americas 1 Canada 1 China 256 China Hong Kong 1 Europe 1 France 1 Germany 3 India 5 Japan 2 Poland 1 South Korea 1 Switzerland 2 THE NETHERLANDS 1 United Kingdom 3 United States 33 Global 312

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38632
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: sales@advtechind.com
Country: United States
ProdList: 6075
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Cambridge Isotope Laboratories, Inc.

Tel: --
Fax: --
Email: cilsales@isotope.com
Country: United States
ProdList: 6598
Advantage: 79

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Cerilliant Corporation

Tel: --
Fax: --
Email: techserv@cerilliant.com
Country: United States
ProdList: 1629
Advantage: 69

Pure Chemistry Scientific Inc

Tel: --
Fax: --
Email: sales@purechems.com
Country: United States
ProdList: 2321
Advantage: 50

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

Spectrum Chemicals & Laboratory Products

Tel: --
Fax: --
Email: sales@spectrumchemical.com
Country: United States
ProdList: 6699
Advantage: 77

Zymed Laboratories Inc.

Tel: --
Fax: --
Country: United States
ProdList: 3068
Advantage: 86

Invitrogen Corporation

Tel: --
Fax: --
Email: supplycenters@invitrogen.com
Country: United States
ProdList: 86
Advantage: 86

Medical Isotopes

Tel: --
Fax: --
Email: stohler@medicalisotopes.com
Country: United States
ProdList: 6181
Advantage: 68

EMD Biosciences, Inc.

Tel: --
Fax: --
Email: technical@calbiochem.com
Country: United States
ProdList: 6529
Advantage: 66

Crescent Chemical Co., Inc.

Tel: --
Fax: --
Email: sales@creschem.com
Country: United States
ProdList: 4597
Advantage: 68

MP Biomedicals, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6561
Advantage: 81

BIOMOL INTERNATIONAL, LP

Tel: --
Fax: --
Email: info@biomol.com
Country: United States
ProdList: 1499
Advantage: 77

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

More

Less

View Lastest Price from Calcifediol Monohydrate manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Calcifediol 63283-36-3
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99.0%min. HPLC
Supply Ability: 10000
Release date: 2024-09-12

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Calcifediol Monohydrate 63283-36-3
Price: US $40.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-05-30

Hebei Weibang Biotechnology Co., Ltd

Product: Calcifediol Monohydrate 63283-36-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-28

63283-36-3, Calcifediol MonohydrateRelated Search:

Tocopheryl acetate Vitamin D2 Paricalcitol Secalciferol Vitamin D3 VITAMIN E NICOTINATE FALECALCITRIOL CALCIFEDIOL Calcifediol Monohydrate Calcitriol CALCIFEDIOL - REFERENCE SPECTRUM 24(R), 25-DIHYDROXYVITAMIN D3 24R,25-DIHYDROXY[26,27-METHYL-3H]-CHOLECALCIFEROL AURORA KA-6724 25-HYDROXY[26,27-METHYL-3H]-CHOLECALCIFEROL calcifediol lactone calcifediol lactol 1ALPHA,25-DIHYDROXY[26,27-METHYL-3H]-CHOLECALCIFEROL

25-HYDROXYVITAMIN D3;25-HYDROXYCHOLECALCIFEROL

Calcifediol monohydrate (25-Hydroxyvitamin D3

Calcifediol /25-Dihydroxyvitamin D3

25-OH-VD3

Calcifediol/25-Hydroxycholecalciferol H20

(5z,7e)-9,10-secocholesta-5,7,10(19)-triene-3b,25-diol monohydrate

VITAMIN D3, 25-HYDROXY-

CALCIDIOL

CALCIFEDIOL

CALCIFEDIOL MONOHYDRATE

25-OH-D3

25-HYDROXYVITAMIN D3

25-hydroxyvitamin d3 monohydrate

25-HYDROXYCHOLECALCIFEROL

25-hydroxycholecalciferol monohydrate

CALCIFEDIOL 1-HYDRATE

9,10-Secocholesta-5,7,10(19)-triene-3,25-diol, monohydrate, (3.beta.,5Z,7E)-

Calcifediol hydrate

25-OH-Vitamin D3

1H-Indene-1-pentanol, 4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-.alpha.,.alpha.,.epsilon.,7a-tetramethyl-, hydrate (1:1), (.epsilon.R,1R,3aS,4E,7aR)-

25-Hydroxyvitamin D3 monohydrate,25-Hydroxycholecalciferol

Calcifediol (75 mg)

(1R,3Z)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-Methylheptan-2-yl]-7a-Methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-Methylidenecyclohexan-1-ol

(5Z,7E)-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-3B,25-DIOL MONOHYDRATE; 25-HYDROXYCHOLECALCIFEROL MONOHYDRATE; 25-OHD3; 25-HYDROXYVITAMIN D3 MONOHYDRATE; 25-HYDROXY VITAMIN D3 MONOHYDRATE;CALCIFEDIOL MONOHYDRATE

25-HYDROXYVITAMIN D3 (95% CP) (23,24,25,26,27-13C5, 99%) 100 UG/ML IN ETHANOL

Calcifediol CRS

25-HYDROXYVITAMIN D3 (23,24,25,26,27-13C5, 99%) CHEMICAL PURITY 95%

Calcifediol Monohydrate USP/EP/BP

(S,Z)-3-((E)-2-((1R,3aS,7aR)-1-((R)-6-Hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexanol hydrate

9,10-Secocholesta-5,7,10(19)-triene-3,25-diol, monohydrate,(3b,5Z,7E)-

TIANFU-CHEM - Calcifediol

Calcifediol (1086108)

(S,Z)-3-(2-((1R,3aS,7aR,E)-1-((R)-6-Hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexan-1-ol hydrate

Ossifying glycol monohydrate

25-hydroxy VD3)

25-Hydroxyvitamin-D3-[13C5]

26,26,26,27,27,27-2H6]-25-HydroxyVitamin D3 Monohydrate

Calcifediol Monohydr

25-HYDROXYVITAMIND3(1.25%)

63283-36-3

C27H44O2xH2O

C27H44O2H2O

C22C5H44O2

BioChemical

Cell Biology

Cell Signaling and Neuroscience

Gene Regulation and Expression

Gene Regulation

Calcidiol, Didrogyl, Hidroferol

APIs

Elisa Kit-plant ELISA Kit

API