ChemicalBook > CAS DataBase List > 4-Morpholinecarbonyl chloride

4-Morpholinecarbonyl chloride

Product Name
4-Morpholinecarbonyl chloride
CAS No.
15159-40-7
Chemical Name
4-Morpholinecarbonyl chloride
Synonyms
4-Morpholinecarbonyl;N-CHLOROFORMYLMORPHOLINE;Morpholincarbonylchlorid;4-CHLOROCARBONYLMORPHOLINE;4-(Chloroformyl)morpholine;MORPHOLINOCARBONYL CHLORIDE;4-MORPHOLINECARBONYL CHLORIDE;MORPHOLINE-4-CARBONYL CHLORIDE;4-MORPHOLINYLCARBONYL CHLORIDE;MORPHOLIN-4-YLCARBONYL CHLORIDE
CBNumber
CB8744478
Molecular Formula
C5H8ClNO2
Formula Weight
149.58
MOL File
15159-40-7.mol
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4-Morpholinecarbonyl chloride Property

Boiling point:
137-138 °C/33 mmHg (lit.)
Density 
1.282 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.498(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
pka
-2.16±0.20(Predicted)
form 
clear liquid
color 
Colorless to Light yellow
BRN 
116257
InChI
InChI=1S/C5H8ClNO2/c6-5(8)7-1-3-9-4-2-7/h1-4H2
InChIKey
XMWFMEYDRNJSOO-UHFFFAOYSA-N
SMILES
C(Cl)(N1CCOCC1)=O
CAS DataBase Reference
15159-40-7(CAS DataBase Reference)
EPA Substance Registry System
4-Morpholinecarbonyl chloride (15159-40-7)
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Safety

Hazard Codes 
Xn
Risk Statements 
14-36/38-40
Safety Statements 
26-30-36-38
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
F 
10-21
HazardClass 
8
PackingGroup 
II
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
348295
Product name
4-Morpholinecarbonyl chloride
Purity
98%
Packaging
25g
Price
$83.15
Updated
2025/07/31
Sigma-Aldrich
Product number
348295
Product name
4-Morpholinecarbonyl chloride
Purity
98%
Packaging
100g
Price
$307
Updated
2023/06/20
TCI Chemical
Product number
M0935
Product name
4-Morpholinylcarbonyl Chloride
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$116
Updated
2025/07/31
TCI Chemical
Product number
M0935
Product name
4-Morpholinylcarbonyl Chloride
Purity
>97.0%(GC)(T)
Packaging
100g
Price
$263
Updated
2025/07/31
TRC
Product number
M723600
Product name
4-Morpholinecarbonyl chloride
Packaging
10g
Price
$50
Updated
2021/12/16
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4-Morpholinecarbonyl chloride Chemical Properties,Usage,Production

Uses

Photographic intermediate

Uses

4-Morpholinecarbonyl chloride may be used in the preparation of a versatile fluorogenic label for biomolecular imaging. It may be used in the synthesis of:

  • morpholine-4-carboxylic acid [4-(2,4-dimethylphenyl)thiazol-2-yl]amide
  • morpholine-4-carboxylic acid [4-(2,4,6-trimethylphenyl)thiazol-2-yl]amide
  • 2-isopropyl-6-methylpyrimidin-4-yl morpholine-4-carboxylate

General Description

4-Morpholinecarbonyl chloride is a photographic intermediate. Rates of solvolysis of 4-morpholinecarbonyl chloride with N-alkyl group in aqueous binary solvents of acetone, ethanol, methanol, methanol-d, 2,2,2-trifluoroethanol, pure water and D2O has been determined. Preparation of 4-morpholinecarbonyl chloride has been reported.

Synthesis

4-Morpholinecarbonyl chloride is prepared by reacting morpholine hydrochloride with phosgene in an inert liquid medium such as toluene and xylene, at 50W150°C, pref. 60W120°C. The morpholine hydrochloride is prepared by dissolving 1 part by weight of morpholine in ≥4 parts of an inert liquid medium and introducing a slightly excessive HCl into the solution under agitation.

4-Morpholinecarbonyl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Morpholinecarbonyl chloride Suppliers

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View Lastest Price from 4-Morpholinecarbonyl chloride manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
Morpholine-4-carbonyl chloride 15159-40-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-10-03
Honest Joy Holdings Limited
Product
4-Morpholinecarbonyl chloride 15159-40-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98.9%
Supply Ability
100 tons
Release date
2022-02-08
Unipharm pharmaceutical industry Co., Ltd
Product
4-Morpholinecarbonyl chloride 15159-40-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
97% GC
Supply Ability
EX: 100kgs
Release date
2021-03-23

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