METHYL 2-BROMO-5-CHLOROBENZOATE
- Product Name
- METHYL 2-BROMO-5-CHLOROBENZOATE
- CAS No.
- 27007-53-0
- Chemical Name
- METHYL 2-BROMO-5-CHLOROBENZOATE
- Synonyms
- Methylz-Bromo-5-Chlorobenzoate;METHYL 2-BROMO-5-CHLOROBENZOATE;Methyl2-Bromo-5-chlorobenzoate>Methyl 2-bromo-5-chlorobenzoate 98%;2-bomo-5-chlorobenzoic acid methyl ester;2-Bromine-5-Chloride Benzioc Acids Methyl;2-BROMO-5-CHLOROBENZOIC ACID METHYL ESTER;Benzoic acid, 2-bromo-5-chloro-, methyl ester
- CBNumber
- CB8776057
- Molecular Formula
- C8H6BrClO2
- Formula Weight
- 249.49
- MOL File
- 27007-53-0.mol
METHYL 2-BROMO-5-CHLOROBENZOATE Property
- Melting point:
- 37-40°C
- Boiling point:
- 278.4±20.0 °C(Predicted)
- Density
- 1.604±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to lump
- color
- White to Orange to Green
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C8H6BrClO2/c1-12-8(11)6-4-5(10)2-3-7(6)9/h2-4H,1H3
- InChIKey
- BIECSXCXIXHDBC-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C1=CC(Cl)=CC=C1Br
- CAS DataBase Reference
- 27007-53-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 20/22-36/37/38
- Safety Statements
- 36/37/39-45-37-26
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M2033
- Product name
- Methyl 2-Bromo-5-chlorobenzoate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $27
- Updated
- 2025/07/31
- Product number
- M2033
- Product name
- Methyl 2-Bromo-5-chlorobenzoate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- M296123
- Product name
- Methyl 2-Bromo-5-chlorobenzoate
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- M296123
- Product name
- Methyl 2-Bromo-5-chlorobenzoate
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- J56281
- Product name
- Methyl 2-Bromo-5-chlorobenzoate
- Packaging
- 25g
- Price
- $59
- Updated
- 2021/12/16
METHYL 2-BROMO-5-CHLOROBENZOATE Chemical Properties,Usage,Production
Chemical Properties
Colorless liquid
Uses
Methyl 2-bromo-5-chlorobenzoate is used as pharmaceutical intermediate.
Synthesis
21739-93-5
27007-53-0
Step 1. To a stirred solution of 2-bromo-5-chlorobenzoic acid (11 g, 46.7 mmol, HPLC retention time = 2.99 min) in methanol (250 mL) at 0 °C was passed dry HCl gas. The reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, the mixture was concentrated under reduced pressure to give an orange colored oil. The oily substance was purified by fast column chromatography using hexane as eluent to afford methyl 2-bromo-5-chlorobenzoate as a colorless oil (10.7 g, 92% yield). Thin-layer chromatography (TLC) Rf = 0.6 (5% ethyl acetate-hexane); high-performance liquid chromatography (HPLC) retention time = 3.48 min (Method A); 1H NMR (CDCl3, 400 MHz) δ 7.78 (d, 1H, J = 2.6 Hz), 7.59 (d, 1H, J = 12.8 Hz), 7.30 (dd, 1H, J = 8.6, 2.5Hz), 3.94 (s, 3H).
References
[1] Patent: US2003/13700, 2003, A1
[2] Patent: US6528503, 2003, B2
[3] Patent: US2002/119992, 2002, A1
METHYL 2-BROMO-5-CHLOROBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 2-BROMO-5-CHLOROBENZOATE Suppliers
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- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
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- sales@chemos-group.com
- Country
- Germany
- ProdList
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View Lastest Price from METHYL 2-BROMO-5-CHLOROBENZOATE manufacturers
- Product
- METHYL 2-BROMO-5-CHLOROBENZOATE 27007-53-0
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-24
- Product
- METHYL 2-BROMO-5-CHLOROBENZOATE 27007-53-0
- Price
- US $10.00-8.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2025-03-14
- Product
- METHYL 2-BROMO-5-CHLOROBENZOATE 27007-53-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-11-29