N-Methyl-D-aspartic acid

Product Name: N-Methyl-D-aspartic acid
CAS No.: 6384-92-5
Chemical Name: N-Methyl-D-aspartic acid
Synonyms: NMDA;n-methylaspartate;N-Me-D-Asp;H-D-MEASP-OH;N-ME-D-ASP-OH;H-D-MEASP-OH HCL;-D-aspartic acid;N-ME-D-ASP-OH HCL;N-Methyl-D-Asp-OH;N-ME-D-ASPARTIC ACID
CBNumber: CB8854056
Molecular Formula: C5H9NO4
Formula Weight: 147.13
MOL File: 6384-92-5.mol

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N-Methyl-D-aspartic acid Property

Melting point:: 187-192 °C
alpha: -28 º (c=1, HCl 6N)
Boiling point:: 267.21°C (rough estimate)
Density: 1.4285 (rough estimate)
refractive index: -15 ° (C=2, H2O)
storage temp.: Sealed in dry,Room Temperature
solubility: Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly)
pka: 2.21±0.23(Predicted)
form: solid
color: white
Water Solubility: slightly soluble
Sensitive: Hygroscopic
Merck: 14,6662
BRN: 1724431
LogP: 1.390 (est)
CAS DataBase Reference: 6384-92-5(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: CI9457000
F: 10
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H319Causes serious eye irritation

H372Causes damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M3262
Product name: N-Methyl-D-aspartic acid
Purity: ≥98% (TLC), solid
Packaging: 1g
Price: $1040
Updated: 2024/03/01

Sigma-Aldrich

Product number: 454575
Product name: N-Methyl-D-aspartic Acid, Hydrate
Purity: Excitatory amino acid neurotransmitter.
Packaging: 100mg
Price: $322
Updated: 2024/03/01

TCI Chemical

Product number: M1360
Product name: N-Methyl-D-aspartic Acid
Purity: >98.0%(T)
Packaging: 100mg
Price: $22
Updated: 2024/03/01

TCI Chemical

Product number: M1360
Product name: N-Methyl-D-aspartic Acid
Purity: >98.0%(T)
Packaging: 1g
Price: $56
Updated: 2024/03/01

Alfa Aesar

Product number: J61361
Product name: N-Methyl-D-aspartic acid, 98+%
Packaging: 50mg
Price: $75.65
Updated: 2024/03/01

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N-Methyl-D-aspartic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

NMDA agonist

Uses

NMDA（N-Methyl-D-aspartic acid）is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.

Definition

ChEBI: An aspartic acid derivative having an N-methyl substituent and D-configuration.

General Description

N-Methyl-D-aspartic acid (NMDA) is an endogenously generated molecule in rat nervous system and endocrine glands. NMDA is present at low level (nmol/g) in the adenohypophysis, hypothalamus, brain, and testis. NMDA is derived from D-Asp by an S-adenosylmethionine-dependent enzyme also referred to as NMDA synthase.

Biological Activity

Prototypic NMDA receptor agonist. Also available as part of the Mixed NMDA Receptor Tocriset™ .

Biochem/physiol Actions

Excitotoxic amino acid. Prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels; important in long-term potentiation, ischemia, and epilepsy.

storage

Room temperature

References

[1] watkins jc, jane de. the glutamate story. br j pharmacol. 2006 jan;147 suppl 1:s100-8.
[2] lafon-cazal m, pietri s, culcasi m, bockaert j. nmda-dependent superoxide production and neurotoxicity. nature. 1993 aug 5;364(6437):535-7.

N-Methyl-D-aspartic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-Methyl-D-aspartic acid manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: N-Me-D-Asp 6384-92-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-04-13

Hebei Zhuanglai Chemical Trading Co Ltd

Product: N-Methyl-D-aspartic acid 6384-92-5
Price: US $45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-12-16

Hebei Dangtong Import and export Co LTD

Product: N-Methyl-D-aspartic acid 6384-92-5
Price: US $3288.00-2680.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2023-09-15

6384-92-5, N-Methyl-D-aspartic acidRelated Search:

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N-METHYL-D-ASPARAGINIC ACID

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(R)-2-(Methylamino)butanedioic acid

N-Methyl-D-Asp-OH

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N-Methyl-D-aspartic Acid Hydrate

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(R)-2-(Methylamino)succinic acid, NMDA

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D-Aspartic acid,N-Methyl-

N-Methyl-D-aspartic acid SynonyMs (R)-2-(MethylaMino)succinic acid

NMDA (N-Methyl-D-aspartic acid)

N-Methyl-d-Aspartic Acid, ≥97%

N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem

n-methylaspartate

n-methyl-d-aspartate

n-methyl-d-asparticaci

(2R)-2-(methylammonio)butanedioate

N-Methyl-D-aspartic acid hydrochloride98+%

N-Me-D-Asp

N-Methyl-D-aspartic acid/C5H9NO4

N-Methyl-D-asparticAcidHydrate&gt

-D-aspartic acid

N-Methyl-D-aspartic acid (NMDA)99%

methyl-D-aspartic acid

N-Methyl-D-aspartic acid USP/EP/BP

NMDA, excitotoxic amino acid

NMDA (mM/ml), excitotoxic amino acid

6384-92-5

C5H9NO4xH2O

Modified Amino Acids

I - Z

BioChemical

Amino Acids and Peptides

Biochemicals and Reagents

Glutamate

amino acids

Glutamate receptor

Pyridines

Inhibitors