Description Characteristics
ChemicalBook > CAS DataBase List > Tesmilifene

Tesmilifene

Description Characteristics
Product Name
Tesmilifene
CAS No.
98774-23-3
Chemical Name
Tesmilifene
Synonyms
DPPE;N,N-Diethyl-2-(4-benzylphenoxy)ethanamine;Depmpe;Marquis;CS-1155;Pato bead;Tesmilifine;TESMILIFENE;Unii-I43T3id6G2;Tesmilifene USP/EP/BP
CBNumber
CB91179551
Molecular Formula
C19H25NO
Formula Weight
283.41
MOL File
98774-23-3.mol
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Tesmilifene Property

Boiling point:
397 ºC
Density 
1.002
Flash point:
117 ºC
storage temp. 
2-8°C
pka
9?+-.0.25(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb181162
Product name
Tesmilifene
Purity
>98%
Packaging
100mg
Price
$510
Updated
2021/12/16
Biorbyt Ltd
Product number
orb181162
Product name
Tesmilifene
Purity
>98%
Packaging
250mg
Price
$765
Updated
2021/12/16
Biorbyt Ltd
Product number
orb181162
Product name
Tesmilifene
Purity
>98%
Packaging
1000mg
Price
$1504.5
Updated
2021/12/16
Crysdot
Product number
CD31000019
Product name
Tesmilifene
Purity
95+%
Packaging
1g
Price
$455
Updated
2021/12/16
DC Chemicals
Product number
DC7316
Product name
Tesmilifene
Purity
>98%
Packaging
1g
Price
$1000
Updated
2021/12/16
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Tesmilifene Chemical Properties,Usage,Production

Description

Tesmilifene is a small molecule chemopotentiator under development by YM BioSciences, a Candian pharmaceutical company that specialises in the development of cancer treatments. It is indicated for use in combination with standard cytotoxic drugs, such as taxanes and anthracyclines, which are widely used in the treatment of metastatic disease – when cancers spread to distant sites in the body.

Characteristics

Tesmilifene is a diphenylmethane derivative that is structurally related to the triphenylethylene derivative tamoxifen but lacks the stilbene bridge and third phenyl ring necessary for binding to the estrogen receptor (ER), and as such, it is not a selective estrogen receptor modulator (SERM). In addition to tamoxifen, tesmilifene is structurally related to diphenylmethane antihistamines like diphenhydramine and hydroxyzine, but is much weaker than these agents in assays of anti-H1 receptor activity, and hence, neither acts as an antihistamine.

Definition

ChEBI: N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine is a diarylmethane.

Tesmilifene Preparation Products And Raw materials

Raw materials

Preparation Products

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Tesmilifene Suppliers

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View Lastest Price from Tesmilifene manufacturers

Hebei Fengqiang Trading Co., LTD
Product
Tesmilifene 98774-23-3
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
500
Release date
2023-08-24
Shanghai Biolang Biotechnology Co., Ltd.
Product
Tesmilifene 98774-23-3
Price
US $99.99-77.77/g
Min. Order
10g
Purity
99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets,Customiz
Supply Ability
1000kgs
Release date
2022-02-23
Zhuozhou Wenxi import and Export Co., Ltd
Product
Tesmilifene 98774-23-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

98774-23-3, TesmilifeneRelated Search:


  • N,N-Diethyl-2-(4-benzylphenoxy)ethanamine
  • DPPE
  • 92981-78-7 (Hydrochloride)
  • Depmpe
  • Ethanamine, N,N-diethyl-2-(4-(phenylmethyl)phenoxy)-
  • Unii-I43T3id6G2
  • Marquis
  • 2-(4-benzylphenoxy)-N,N-diethyl-ethanamine
  • TESMILIFENE
  • CS-1155
  • Tesmilifine
  • Tesmilifene USP/EP/BP
  • Pato bead
  • 98774-23-3
  • C18H14F3N3O4S3
  • API