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4-(cyclohexylsulfamoyl)benzoic acid

Product Name
4-(cyclohexylsulfamoyl)benzoic acid
CAS No.
6314-70-1
Chemical Name
4-(cyclohexylsulfamoyl)benzoic acid
Synonyms
NSC23005;INK4C-IN-2;NSC23005 free acid;NSC23005, 10 mM in DMSO;4-(N-Cyclohexylsulfamoyl)benzoic acid;Benzoic acid, 4-[(cyclohexylamino)sulfonyl]-
CBNumber
CB91257767
Molecular Formula
C13H17NO4S
Formula Weight
283.34
MOL File
6314-70-1.mol
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4-(cyclohexylsulfamoyl)benzoic acid Property

Melting point:
259-260 °C
Boiling point:
473.4±47.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
pka
3.54±0.10(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0296513
Product name
4-(CYCLOHEXYLSULFAMOYL)BENZOIC ACID
Purity
95.00%
Packaging
5MG
Price
$498.92
Updated
2021/12/16
DC Chemicals
Product number
DC9989
Product name
NSC23005freeacid
Purity
>98%
Packaging
1g
Price
$1200
Updated
2021/12/16
DC Chemicals
Product number
DC9989
Product name
NSC23005freeacid
Purity
>98%
Packaging
100mg
Price
$350
Updated
2021/12/16
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4-(cyclohexylsulfamoyl)benzoic acid Chemical Properties,Usage,Production

Description

NSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM).

Uses

INK4C-IN-2 (Compound 40) is the inhibitor for INK4C (also known as p18) and the activator for CDK4/6. INK4C-IN-2 increases the number and expansion capacity of mouse and human hematopoietic stem cells (HSCs) with EC50 of 5.21 nM, promotes the self-renewal and multilineage differentiation of HSCs. INK4C-IN-2 improves the expansion and long-term hematopoietic reconstruction ability of HSCs in mouse bone marrow transplantation model[1].

References

[1] Xie XQ, et al., Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci Rep. 2015 Dec 18;5:18115. DOI:10.1038/srep18115

4-(cyclohexylsulfamoyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(cyclohexylsulfamoyl)benzoic acid Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
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Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
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View Lastest Price from 4-(cyclohexylsulfamoyl)benzoic acid manufacturers

Career Henan Chemical Co
Product
4-(cyclohexylsulfamoyl)benzoic acid 6314-70-1
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-25