ChemicalBook > CAS DataBase List > YM 26734

YM 26734

Product Name
YM 26734
CAS No.
144337-18-8
Chemical Name
YM 26734
Synonyms
YM 26734;4-(3,5-Didodecanoyl-2,4,6-trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman;1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one;1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-1-dodecanone;1-Dodecanone, 1,1'-(5-(3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxy-1,3-phenylene)bis-
CBNumber
CB91317214
Molecular Formula
C45H62O8
Formula Weight
730.97
MOL File
144337-18-8.mol
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YM 26734 Property

storage temp. 
Store at -20°C
solubility 
Soluble to 100 mM in DMSO and to 100 mM in ethanol
form 
Powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1226
Product name
YM-26734
Purity
≥95% (HPLC)
Packaging
5MG
Price
$146
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1226
Product name
YM-26734
Purity
≥95% (HPLC)
Packaging
25MG
Price
$578
Updated
2024/03/01
Cayman Chemical
Product number
17631
Product name
YM-26734
Purity
≥95%
Packaging
1mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
17631
Product name
YM-26734
Purity
≥95%
Packaging
5mg
Price
$130
Updated
2024/03/01
Cayman Chemical
Product number
17631
Product name
YM-26734
Purity
≥95%
Packaging
10mg
Price
$239
Updated
2024/03/01
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YM 26734 Chemical Properties,Usage,Production

Uses

YM-26734 is a derivative of a compound isolated from the fruit of H. amygdaline that competitively inhibits rabbit platelet sPLA2 which is a diverse family of low molecular weight PLA2s with tissue-specific expression patterns and actions.

Biological Activity

Competitive inhibitor of secretory phospholipase A 2 (sPLA 2 ) that exhibits a broad inhibitory profile to several sPLA 2 s (IC 50 values are 0.2, 1, 1, 1 and 3 μ M for sPLA 2 -X, -IIA, -IID, -V and -IIE respectively). Displays minimal activity at sPLA 2 -IIF and no activity at cytosolic PLA 2 , cyclooxygenase and lipoxygenase. Ameliorates local inflammatory responses in TPA-induced mouse ear edema.

storage

Store at -20°C

YM 26734 Preparation Products And Raw materials

Raw materials

Preparation Products

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YM 26734 Suppliers

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144337-18-8, YM 26734Related Search:

YM155 1-(2-Methoxyethyl)-2-Methyl-4,9-dioxo-3-(pyrazin-2-ylMethyl)-4,9-dihydro-1H-naphtho[2,3-d]iMidazol-3-iuM chloride BTP2 5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate YM-53601 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide YM17E

  • 1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one
  • YM 26734
  • 1-Dodecanone, 1,1'-(5-(3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxy-1,3-phenylene)bis-
  • 4-(3,5-Didodecanoyl-2,4,6-trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman
  • 1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-1-dodecanone
  • 144337-18-8
  • C45H62O8