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6-aminocarbovir

Product Name
6-aminocarbovir
CAS No.
124752-25-6
Chemical Name
6-aminocarbovir
Synonyms
6-aminocarbovir;Abacavir Impurity C;Descyclopropyl Abacavir;Abacavir amine impurity;(Abacavir EP Impurity C);Abacavir Related CoMpound A;Abacavir Sulfate Impurity C;Descyclopropyl Abacavir (USP);Abacavir Sulfate EP Impurity C;Abacavir USP Related Compound A
CBNumber
CB91326700
Molecular Formula
C11H14N6O
Formula Weight
246.27
MOL File
124752-25-6.mol
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6-aminocarbovir Property

Melting point:
180-182°C
Boiling point:
628.2±65.0 °C(Predicted)
Density 
1.75±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
pka
14.86±0.10(Predicted)
color 
Off-White to Pale Yellow
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Safety

Hazard Codes 
Xi
Risk Statements 
41-43
Safety Statements 
26-36/37-39
HS Code 
2933599550
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2064
Product name
Abacavir Related Compound A
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
50mg
Price
$803
Updated
2024/03/01
Sigma-Aldrich
Product number
1000420
Product name
Abacavir Related Compound A
Packaging
20mg
Price
$1360
Updated
2024/03/01
TRC
Product number
D288865
Product name
DescyclopropylAbacavir
Packaging
5mg
Price
$145
Updated
2021/12/16
Usbiological
Product number
008302
Product name
Descyclopropyl Abacavir
Packaging
5mg
Price
$460
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21165
Product name
Descyclopropyl abacavir
Packaging
2mg
Price
$578.1
Updated
2021/12/16
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6-aminocarbovir Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Descyclopropyl Abacavir (Abacavir EP Impurity C; Abacavir Related Compound A) is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Uses

Abacavir Intermediate.

6-aminocarbovir Preparation Products And Raw materials

Raw materials

Preparation Products

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6-aminocarbovir Suppliers

Canada 1 China 26 India 8 United Kingdom 2 United States 7 Global 44
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

124752-25-6, 6-aminocarbovirRelated Search:

Abacavir Abacavir Carboxylate Abacavir sulfate (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol 2,6-Diaminopurine Abacavir 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)- Abacavir Related CoMpound D (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride Abacavir (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride Abacavir-d4 Abacavir 5’-Phosphate 2-Amino-6-cyclopropylamino-9H-purine Abacavir 5'-Glucuronide Abacavir trans-Abacavir Hydrochloride Abacavir Impurity 1

  • (1α,4α)-4-(2,6-Diamino-9H-purin-9-yl)-2-cyclopentenyl-carbinol
  • Abacavir Impurity 3(Abacavir EP Impurity C)
  • (Abacavir EP Impurity C)
  • Abacavir Related CoMpound A
  • 6-aminocarbovir
  • (-)-2,6-Diamino-9-[(1R)-4β-(hydroxymethyl)-2-cyclopentene-1β-yl]-6,9-dihydro-1H-purine
  • 2-Cyclopentene-1-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, (1S-cis)-
  • Descyclopropyl Abacavir
  • Abacavir Related Compound A (20 mg) ([4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol)
  • (1S,4R)-4-(2,6-DiaMino-9H-purin-9-yl)-2-cyclopentene-1-Methanol
  • [(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol
  • Descyclopropyl Abacavir (USP)
  • 2-Cyclopentene-1-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, (1S,4R)-
  • Abacavir amine impurity
  • [(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-en-1- yl]methanol
  • Abacavir Related Compound A ([4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol) (1000420)
  • Abacavir Sulfate - Impurity C (Freebase)
  • Abacavir USP Related Compound A
  • Abacavir Impurity C
  • Abacavir Sulfate Impurity C
  • Abacavir Sulfate EP Impurity C
  • 124752-25-6
  • Bases & Related Reagents
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
  • Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals