6-aminocarbovir

Product Name: 6-aminocarbovir
CAS No.: 124752-25-6
Chemical Name: 6-aminocarbovir
Synonyms: 6-aminocarbovir;Abacavir Impurity C;Descyclopropyl Abacavir;Abacavir amine impurity;(Abacavir EP Impurity C);Abacavir Related CoMpound A;Abacavir Sulfate Impurity C;Descyclopropyl Abacavir (USP);Abacavir Sulfate EP Impurity C;Abacavir USP Related Compound A
CBNumber: CB91326700
Molecular Formula: C11H14N6O
Formula Weight: 246.27
MOL File: 124752-25-6.mol

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6-aminocarbovir Property

Melting point:: 180-182°C
Boiling point:: 628.2±65.0 °C(Predicted)
Density: 1.75±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
pka: 14.86±0.10(Predicted)
color: Off-White to Pale Yellow

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Safety

Hazard Codes: Xi
Risk Statements: 41-43
Safety Statements: 26-36/37-39
HS Code: 2933599550

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H318Causes serious eye damage
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2064
Product name: Abacavir Related Compound A
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 50mg
Price: $803
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1000420
Product name: Abacavir Related Compound A
Packaging: 20mg
Price: $1360
Updated: 2024/03/01

TRC

Product number: D288865
Product name: DescyclopropylAbacavir
Packaging: 5mg
Price: $145
Updated: 2021/12/16

Usbiological

Product number: 008302
Product name: Descyclopropyl Abacavir
Packaging: 5mg
Price: $460
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21165
Product name: Descyclopropyl abacavir
Packaging: 2mg
Price: $578.1
Updated: 2021/12/16

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6-aminocarbovir Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Descyclopropyl Abacavir (Abacavir EP Impurity C; Abacavir Related Compound A) is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Uses

Abacavir Intermediate.

6-aminocarbovir Preparation Products And Raw materials

Raw materials

Preparation Products

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6-aminocarbovir Suppliers

Canada 1 China 26 India 8 United Kingdom 2 United States 7 Global 44

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124752-25-6, 6-aminocarbovirRelated Search:

Abacavir Abacavir Carboxylate Abacavir sulfate (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol 2,6-Diaminopurine Abacavir 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)- Abacavir Related CoMpound D (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride Abacavir (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride Abacavir-d4 Abacavir 5’-Phosphate 2-Amino-6-cyclopropylamino-9H-purine Abacavir 5'-Glucuronide Abacavir trans-Abacavir Hydrochloride Abacavir Impurity 1

(1α,4α)-4-(2,6-Diamino-9H-purin-9-yl)-2-cyclopentenyl-carbinol

Abacavir Impurity 3(Abacavir EP Impurity C)

(Abacavir EP Impurity C)

Abacavir Related CoMpound A

6-aminocarbovir

(-)-2,6-Diamino-9-[(1R)-4β-(hydroxymethyl)-2-cyclopentene-1β-yl]-6,9-dihydro-1H-purine

2-Cyclopentene-1-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, (1S-cis)-

Descyclopropyl Abacavir

Abacavir Related Compound A (20 mg) ([4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol)

(1S,4R)-4-(2,6-DiaMino-9H-purin-9-yl)-2-cyclopentene-1-Methanol

[(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol

Descyclopropyl Abacavir (USP)

2-Cyclopentene-1-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, (1S,4R)-

Abacavir amine impurity

[(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-en-1- yl]methanol

Abacavir Related Compound A ([4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol) (1000420)

Abacavir Sulfate - Impurity C (Freebase)

Abacavir USP Related Compound A

Abacavir Impurity C

Abacavir Sulfate Impurity C

Abacavir Sulfate EP Impurity C

124752-25-6

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Intermediates & Fine Chemicals

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