4-Iodo-1,2-dimethylbenzene
- Product Name
- 4-Iodo-1,2-dimethylbenzene
- CAS No.
- 31599-61-8
- Chemical Name
- 4-Iodo-1,2-dimethylbenzene
- Synonyms
- 4-IODO-2-XYLENE;4-IODO-O-XYLENE;4-Iodo-o-xylene>4-Iodo-1,2-dimethylb;4-Iodo-o-xylene, 98+%;3,4-DIMETHYLIODOBENZENE;3,4-Dimethjyliodobenzene;3,4-Dimethylphenyl iodide;4-IODO-1,2-DIMETHYLBENZENE;3,4-DIMETHYL-1-IODOBENZENE
- CBNumber
- CB9143469
- Molecular Formula
- C8H9I
- Formula Weight
- 232.06
- MOL File
- 31599-61-8.mol
4-Iodo-1,2-dimethylbenzene Property
- Melting point:
- -2.9°C (estimate)
- Boiling point:
- 106-108 °C13 mm Hg(lit.)
- Density
- 1.633 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.603(lit.)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- clear liquid
- color
- Colorless to Brown
- Sensitive
- Light Sensitive
- BRN
- 1905729
- InChI
- InChI=1S/C8H9I/c1-6-3-4-8(9)5-7(6)2/h3-5H,1-2H3
- InChIKey
- CSFRCLYFVINMBZ-UHFFFAOYSA-N
- SMILES
- C1(C)=CC=C(I)C=C1C
- CAS DataBase Reference
- 31599-61-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, 4-iodo-1,2-dimethyl-(31599-61-8)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- I0560
- Product name
- 4-Iodo-o-xylene
- Packaging
- 25G
- Price
- $104
- Updated
- 2025/07/31
- Product number
- I705510
- Product name
- 4-Iodo-1,2-dimethylbenzene
- Packaging
- 10g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 006559
- Product name
- 4-Iodo-o-xylene
- Packaging
- 100g
- Price
- $109
- Updated
- 2021/12/16
- Product number
- 004948
- Product name
- 4-Iodo-o-xylene
- Purity
- 98%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- 006559
- Product name
- 4-Iodo-o-xylene
- Packaging
- 5g
- Price
- $11
- Updated
- 2021/12/16
4-Iodo-1,2-dimethylbenzene Chemical Properties,Usage,Production
Chemical Properties
clear yellow to red-brown liquid
Uses
1-Iodo-3,4-dimethylbenzene (4-iodo-o-xylene, 3,4-dimethyliodobenzene) may be used in the synthesis of the following:
- 3-arylacrylamide
- 3,3-diaryl substituted acrylamide
- 3-arylpropylamine
- di-tert-butyl 1-(3,4-dimethylphenyl)hydrazine-1,2-dicarboxylate
- 2,3,7,8-tetramethyldibenzofuran
- N-(3-(3,4-Dimethylphenyl)-2-phthalimidopropionyl)-2-methylthioaniline
General Description
1-Iodo-3,4-dimethylbenzene (4-iodo-o-xylene, 3,4-dimethyliodobenzene) is an aryl halide. Its synthesis, NMR and IR spectra has been reported. Its nitration reaction and copper catalyzed trifluoromethylation reaction has been studied.
Synthesis
95-47-6
31599-61-8
GENERAL STEPS: To a solution of 1,2-dimethylbenzene (o-xylene, 0.106 g, 1 mmol) in acetonitrile (10 mL) was sequentially added iodine (1 mmol, 0.126 g) and polymer-loaded periodate (0.6 g, 1.05 mmol). The reaction mixture was stirred at 40 °C for 1 hour. The progress of the reaction was monitored by thin layer chromatography (TLC) and the unfolding agent was a solvent mixture of ethyl acetate and hexane (1:9, v/v). After completion of the reaction, the mixture was cooled to room temperature and filtered. Excess iodine in the filtrate was removed by adding sodium bisulfite solution (1 M) dropwise. The organic layer was separated, dried with anhydrous magnesium sulfate, filtered and evaporated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography, the eluent being a solvent mixture of hexane and ethyl acetate. The final product was 3,4-dimethyl iodobenzene in 95% isolated yield with a boiling point of 235 °C (literature value: 234 °C).
References
[1] Bulletin of the Chemical Society of Ethiopia, 2014, vol. 28, # 2, p. 305 - 308
[2] Tetrahedron Letters, 2011, vol. 52, # 18, p. 2413 - 2414
[3] Advanced Synthesis and Catalysis, 2005, vol. 347, # 15, p. 1925 - 1928
[4] Patent: EP1595862, 2005, A1. Location in patent: Page/Page column 9
[5] European Journal of Organic Chemistry, 2017, vol. 2017, # 22, p. 3234 - 3239
4-Iodo-1,2-dimethylbenzene Preparation Products And Raw materials
Raw materials
Preparation Products
4-Iodo-1,2-dimethylbenzene Suppliers
- Tel
- --
- Fax
- --
- brunschwig@brunschwig.nl
- Country
- The Netherlands
- ProdList
- 4996
- Advantage
- 67
View Lastest Price from 4-Iodo-1,2-dimethylbenzene manufacturers
- Product
- 4-iodo-1,2-dimethylbenzene 31599-61-8
- Price
- US $930.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 300MT/year
- Release date
- 2019-12-24
- Product
- 4-Iodo-1,2-dimethylbenzene 31599-61-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-04-17
- Product
- 4-Iodo-1,2-dimethylbenzene 31599-61-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13