4-Chloro-2-methylthiopyrimidine

Product Name: 4-Chloro-2-methylthiopyrimidine
CAS No.: 49844-90-8
Chemical Name: 4-Chloro-2-methylthiopyrimidine
Synonyms: 4-CHLORO-2-(METHYLTHIO)PYRIMIDINE;4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE;4-Chloro-2-(Methylthio)py...;2-methylthio-4-chloropyrimine;6-Chloro-2-methylthiopyrimidine;2-(Methylthio)-4-chloropyrimidine;4-Chloro-2-methylthiopyrimidine,97%;PYRIMIDINE, 4-CHLORO-2-(METHYLTHIO)-;4-Chloro-2-(methylthio)pyrimidine 97%;4-Chloro-2-(methylmercapto)pyrimidine
CBNumber: CB9149799
Molecular Formula: C5H5ClN2S
Formula Weight: 160.62
MOL File: 49844-90-8.mol

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4-Chloro-2-methylthiopyrimidine Property

Melting point:: −2 °C(lit.)
Boiling point:: 139-140 °C36 mm Hg(lit.)
Density: 1.381 g/mL at 25 °C(lit.)
refractive index: n20/D 1.6(lit.)
Flash point:: >230 °F
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: liquid
pka: -0.56±0.20(Predicted)
color: Colorless to Red to Green
Water Solubility: Not miscible or difficult to mix in water.
Sensitive: Hygroscopic
BRN: 118042
InChIKey: DFOHHQRGDOQMKG-UHFFFAOYSA-N
CAS DataBase Reference: 49844-90-8(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45
RIDADR: UN 1760 8/PG 2
WGK Germany: 3
F: 10-13-23
Hazard Note: Corrosive/Hygroscopic
HazardClass: 8
PackingGroup: III
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 145289
Product name: 4-Chloro-2-methylthiopyrimidine
Purity: 98%
Packaging: 10g
Price: $51
Updated: 2024/03/01

Sigma-Aldrich

Product number: 145289
Product name: 4-Chloro-2-methylthiopyrimidine
Purity: 98%
Packaging: 50g
Price: $96.8
Updated: 2024/03/01

TCI Chemical

Product number: C3087
Product name: 4-Chloro-2-(methylthio)pyrimidine
Purity: >98.0%(GC)
Packaging: 5g
Price: $62
Updated: 2024/03/01

TCI Chemical

Product number: C3087
Product name: 4-Chloro-2-(methylthio)pyrimidine
Purity: >98.0%(GC)
Packaging: 25g
Price: $186
Updated: 2024/03/01

Alfa Aesar

Product number: B21481
Product name: 4-Chloro-2-(methylthio)pyrimidine, 98%
Packaging: 50g
Price: $269
Updated: 2021/12/16

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4-Chloro-2-methylthiopyrimidine Chemical Properties,Usage,Production

Chemical Properties

Clear yellow to brown liquid

Uses

It finds it application as a building block used in medicinal chemistry synthesis. 4-Chloro-2-methylthiopyrimidine is used in the total synthesis of the marine alkaloid variolin B1 and 2-hydroxy-4-pyrimidinecarboxylic acid. It is also used in the synthesis of 2,4-disubstituted pyrimidines, a novel class of KDR kinase inhibitors.

Uses

4-Chloro-2-methylthiopyrimidine was used in the total synthesis of the marine alkaloid variolin B1 and 2-hydroxy-4-pyrimidinecarboxylic acid. It was used in the synthesis of 2,4-disubstituted pyrimidines, a novel class of KDR kinase inhibitors. It was used as building block in medicinal chemistry synthesis.

4-Chloro-2-methylthiopyrimidine Preparation Products And Raw materials

Raw materials

Phosphorus oxychloride 2-Thiouracil 2-Methylthio-4-pyrimidinol Iodomethane

Preparation Products

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4-Chloro-2-methylthiopyrimidine Suppliers

Americas 1 Belgium 1 China 219 Europe 1 Germany 5 India 12 Japan 1 Switzerland 1 United Kingdom 10 United States 31 Global 282

Alfa Aesar, Thermo Fisher Scientific

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Email: es@alfa.com
Country: Germany
ProdList: 5123
Advantage: 58

CHEMOS GmbH & Co. KG

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Email: chemos@chemos.de
Country: Germany
ProdList: 6727
Advantage: 58

ABCR GmbH & CO. KG

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Email: info@abcr.de
Country: Germany
ProdList: 6831
Advantage: 75

Service Chemical Inc.

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Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

ACTIVATE SCIENTIFIC GmbH

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Email: info@activate-scientific.com
Country: Germany
ProdList: 2856
Advantage: 61

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View Lastest Price from 4-Chloro-2-methylthiopyrimidine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 4-Chloro-2-methylthiopyrimidine 49844-90-8
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-11-12

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Chloro-2-methylthiopyrimidine 49844-90-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-05-14

Hebei Zhanyao Biotechnology Co. Ltd

Product: 4-Chloro-2-methylthiopyrimidine 49844-90-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-10-15

49844-90-8, 4-Chloro-2-methylthiopyrimidineRelated Search:

Phenyl chlorothionocarbonate ISOMETHIOZIN Pyrimidine Sulfamerazine tert-Butyldimethylsilyl chloride Meclofenoxate hydrochloride 2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate 4-Chloropyrimidine 2-Chloro-5-chloromethylpyridine Chloromethyltrimethylsilane Chlorantraniliprole MCPA SODIUM Pirimiphos-methyl Thioridazine Difluorochloromethane 4,6-DICHLORO-2-METHYLTHIO-5-PHENYLPYRIMIDINE 5-Bromo-4-chloro-2-(methylthio)pyrimidine ,97%,5-Bromo-4-chloro-2-(methylthio)pyrimidine Chloromethyl methyl ether

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4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE

4-Chloro-2-(methylthio)pyrimidine 97%

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4-Chloro-2-(methylthio)pyrimidine ,98%

4-Chloro-2-(Methylthio)py...

4-Chloro-2-(methylmercapto)pyrimidine, 4-Chloro-2-(methylsulphanyl)pyrimidine

4-Chloro-2-methylthiopyrimidine,97%

4-Chloro-2-methylthiopyrimidine 4-Chloro-2-(methylthio)pyrimidine

6-Chloro-2-methylthiopyrimidine

4-Chloro-2-methylthiopyrimidine≥ 99% (GC)

PYRIMIDINE, 4-CHLORO-2-(METHYLTHIO)-

4-CHLORO-2-(METHYLTHIO)PYRIMIDINE

49844-90-8

C5H5ClN2S

Building Blocks

Heterocyclic Building Blocks

Halogenated Heterocycles

Pyrimidines

Pyrazines, Pyrimidines & Pyridazines

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyrimidines

PyrimidinesHeterocyclic Building Blocks

Pyrimidine

Halides

Pyrazines, Pyrimidines & Pyridazines

Heterocycle-Pyrimidine series