Uses
ChemicalBook > CAS DataBase List > 3,4-Difluoroanisole

3,4-Difluoroanisole

Uses
Product Name
3,4-Difluoroanisole
CAS No.
115144-40-6
Chemical Name
3,4-Difluoroanisole
Synonyms
3,4-DIFLUORO-1-METHOXYBENZENE;3,4-DIFLUOROANISOLE;3,4-Difluoroanisole>3,4-Difluoroanisole98%;3,4,5-TRIFLUORO ANISOLE;3,4-Difluoroanisole 98%;3,4-Difluoroanisole, 97%;"3,4-Difluoroanisole, 99%";1,2-DIFLUORO-4-METHOXY-BENZENE;Benzene, 1,2-difluoro-4-methoxy-
CBNumber
CB9155486
Molecular Formula
C7H6F2O
Formula Weight
144.12
MOL File
115144-40-6.mol
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3,4-Difluoroanisole Property

Boiling point:
101.45°C (rough estimate)
Density 
1.216 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.469(lit.)
Flash point:
131 °F
storage temp. 
Sealed in dry,Room Temperature
form 
Liquid
color 
Clear colorless
Specific Gravity
1.216
BRN 
6717610
InChI
InChI=1S/C7H6F2O/c1-10-5-2-3-6(8)7(9)4-5/h2-4H,1H3
InChIKey
DSEVNUCNUTYYHW-UHFFFAOYSA-N
SMILES
C1(F)=CC=C(OC)C=C1F
CAS DataBase Reference
115144-40-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,F,Xn
Risk Statements 
10-36/37/38
Safety Statements 
16-26-36-7/9
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
Hazard Note 
Flammable
HazardClass 
3
PackingGroup 
III
HS Code 
29093090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D2856
Product name
3,4-Difluoroanisole
Purity
>97.0%(GC)
Packaging
5g
Price
$52
Updated
2025/07/31
TCI Chemical
Product number
D2856
Product name
3,4-Difluoroanisole
Purity
>97.0%(GC)
Packaging
25g
Price
$156
Updated
2025/07/31
TRC
Product number
D445598
Product name
3,4-Difluoroanisole
Packaging
1g
Price
$55
Updated
2021/12/16
TRC
Product number
D445598
Product name
3,4-Difluoroanisole
Packaging
2.5g
Price
$65
Updated
2021/12/16
SynQuest Laboratories
Product number
2607-3-09
Product name
3,4-Difluoroanisole
Purity
98%
Packaging
100g
Price
$85
Updated
2021/12/16
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3,4-Difluoroanisole Chemical Properties,Usage,Production

Uses

3,4-Difluoroanisole is an organic intermediate that can be prepared by etherifying 3,4-difluorophenol with iodomethane.

Chemical Properties

CLEAR COLOURLESS LIQUID

Synthesis Reference(s)

[1] Method for preparing 3,4-difluoroanisole. CN105523904A

Synthesis

The method for preparing 3,4-difluoroanisole includes the steps that compound 3,4-difluorophenol is dissolved in acetonitrile, potassium carbonate is weighed, methyl iodide is dripped, and the mixture is reacted overnight at an indoor temperature; thin-1ayer chromatography is carried out on the next day, and it is discovered that the raw materials are completely reacted; reaction liquid is poured into water to be fully stirred, the lower layer organic phase is separated, then dichloromethane and water are added, and full washing and separation are carried out; afterwards, washing with water is conducted twice, and the organic phase is separated, dried and subjected to atmospheric distillation; the product, dichloromethane and residual acetonitrile are azeotropic, a vacuum pump is used for conducting reduced pressure distillation from the temperature of 60°C, colorless clear liquid is steamed out when the temperature is raised to 120°C, and accordingly the compound 3,4-difluoroanisole is obtained. 

3,4-Difluoroanisole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3,4-Difluoroanisole manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3,4-Difluoroanisole 115144-40-6
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-13
Hebei Chuanghai Biotechnology Co,.LTD
Product
3,4-Difluoroanisole 115144-40-6
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-15
Career Henan Chemical Co
Product
3,4-Difluoroanisole 115144-40-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98
Supply Ability
200kg
Release date
2019-09-10

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