ChemicalBook > CAS DataBase List > 2-Chloro-4'-fluoroacetophenone

2-Chloro-4'-fluoroacetophenone

Product Name
2-Chloro-4'-fluoroacetophenone
CAS No.
456-04-2
Chemical Name
2-Chloro-4'-fluoroacetophenone
Synonyms
AKOS BBS-00004073;2-Chloro-4'-fluoroac;LABOTEST-BB LT00233195;Fluorophenacylchloride;Ticagrelor Impurity 285;4-Fluorchloracetophenone;p-Fluorophenacylchloride;2-chloro-4-fluorophenone;FLUVASTATIN INTERMEDIATES;p-Fluorophenacyl chloride
CBNumber
CB9201396
Molecular Formula
C8H6ClFO
Formula Weight
172.58
MOL File
456-04-2.mol
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2-Chloro-4'-fluoroacetophenone Property

Melting point:
47-50 °C(lit.)
Boiling point:
247°C
Density 
1.2752 (estimate)
vapor pressure 
1.9Pa at 27.1℃
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
form 
Flakes or Platelets
color 
Light yellow to yellow-beige
Water Solubility 
Insoluble in water.
Sensitive 
Lachrymatory
BRN 
637860
InChI
InChI=1S/C8H6ClFO/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2
InChIKey
UJZWJOQRSMOFMA-UHFFFAOYSA-N
SMILES
C(=O)(C1=CC=C(F)C=C1)CCl
CAS DataBase Reference
456-04-2(CAS DataBase Reference)
NIST Chemistry Reference
«ALPHA»-chloro-para-fluoroacetophenone(456-04-2)
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Safety

Hazard Codes 
Xi,C,T
Risk Statements 
36/37/38-34-23/25-36
Safety Statements 
26-28-45-36/37/39-27
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
AM6550000
F 
9-19
Hazard Note 
Corrosive/Lachrymatory
HazardClass 
8
PackingGroup 
II
HS Code 
29147000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
132888
Product name
2-Chloro-4′-fluoroacetophenone
Purity
99%
Packaging
25g
Price
$282
Updated
2023/06/20
Sigma-Aldrich
Product number
132888
Product name
2-Chloro-4′-fluoroacetophenone
Purity
99%
Packaging
100g
Price
$1000
Updated
2023/06/20
TCI Chemical
Product number
C1977
Product name
2-Chloro-4'-fluoroacetophenone
Purity
>98.0%(GC)
Packaging
5g
Price
$20
Updated
2025/07/31
TCI Chemical
Product number
C1977
Product name
2-Chloro-4'-fluoroacetophenone
Purity
>98.0%(GC)
Packaging
25g
Price
$66
Updated
2025/07/31
TRC
Product number
F595330
Product name
4-FluorophenacylChloride
Packaging
25g
Price
$195
Updated
2021/12/16
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2-Chloro-4'-fluoroacetophenone Chemical Properties,Usage,Production

Chemical Properties

LIGHT YELLOW TO YELLOW-BEIGE FLAKES OR PLATELETS

Uses

1-methyl-2-(4-methylthio)phenyl-4-(4-fluoro)phenylimidazole which was synthesized by condensing N-methyl-4-(methylthio)benzamidine with 2-chloro-4?-fluoroacetophenone.

General Description

2-Chloro-4′-fluoroacetophenone on condensation with N-methyl-4-(methylthio)benzamidine yields 1-methyl-2-(4-methylthio)phenyl-4-(4-fluoro)phenylimidazole.

2-Chloro-4'-fluoroacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-4'-fluoroacetophenone Suppliers

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View Lastest Price from 2-Chloro-4'-fluoroacetophenone manufacturers

Moxin Chemicals
Product
Voriconazole 456-04-2
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98
Supply Ability
10000000
Release date
2025-02-18
Hebei Yiduo Import and Export Co., Ltd.
Product
2-Chloro-4'-fluoroacetophenone 456-04-2
Price
US $100.00-80.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000000
Release date
2025-03-12
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Chloro-4'-fluoroacetophenone 456-04-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-13

456-04-2, 2-Chloro-4'-fluoroacetophenoneRelated Search:

2-Bromoacetophenone 2-Chloroacetophenone 4-Fluorophenethylamine 4-Nitroacetophenone Sodium chloride Trifluoroacetophenone Choline chloride 3-Nitroacetophenone L-PICEIN Ammonium chloride 4'-(Trifluoromethyl)acetophenone 1-(2,6-Difluorophenyl)ethan-1-one 4'-Hydroxyacetophenone 3'-Fluoroacetophenone 2',4'-Difluoroacetophenone 4'-Methylacetophenone 4-Fluoroacetophenone Thionyl chloride

  • .alpha.-Chloro-p-Fluoroacetophenone
  • AKOS BBS-00004073
  • ALPHA-CHLORO-4-FLUOROACETOPHENONE
  • LABOTEST-BB LT00233195
  • 2-CHLORO-1-(4-FLUOROPHENYL)ETHANONE
  • 2-Chloro-4'-Fluoroacetophenone 2-Chloro-1-(4-Fluorophenyl)ethanone
  • FLUVASTATIN INTERMEDIATES
  • N-isopropyl-3-(4'-fluorophenyl)indole
  • 3-(3-4-fluorophenyl-1-isopropyl-1H-indole-2-y) propenal
  • 4-Fluorchloracetophenone
  • 4'-Fluoro-2-chloroacetophenone
  • α-CHLORO-P-FLUORO ACETOPHENONE
  • Fluorophenacylchloride
  • A-CHLORO-4-FLUOROACETOPHENONE
  • à-chloro-4-fluoroacetophenone
  • P-FLUORO-ALPHA-CHLOROACETOPHENONE
  • omega-chloro-4-fluoroacetophenone
  • ω-chloro-4-fluoroacetophenone
  • 4-Fluorophenacyl chloride 99%
  • 4-Fluorophenacylchloride99%
  • 4-Fluor-omega-chloracetophenon
  • 4-fluorophenacyl chloride,2-chloro-1-(4-fluorophenyl)ethanone
  • ω-Chloro-4-fluoroacetophenone, 4-Fluorophenacyl chloride
  • a-Chloro-p-fluoroacetophenone
  • 2-chloro-1-(4-fluorophenyl)-ethanon
  • 2-chloro-4’-fluoro-acetophenon
  • 2-Chloro-4'-fluoroacetophenone, 2-Chloro-1-(4-fluorophenyl)ethan-1-one
  • 2-Bhloro-4'-fluoroacetophenone
  • Acetophenone, 2-chloro-4'-fluoro-
  • Acetophenone,2-chloro-4’-fluoro-
  • alpha-Chloro-p-fluoroacetophenone
  • Ethanone, 2-chloro-1-(4-fluorophenyl)-
  • Ethanone,2-chloro-1-(4-fluorophenyl)-(9CI)
  • p-Fluorophenacyl chloride
  • p-Fluorophenacylchloride
  • 4-FLUOROPHENACYL CHLORIDE
  • 2-Chloro-4'-fluoroac
  • 2-Chloro-4'-fluoroacetophenone
  • 2-chloro-4-fluorophenone
  • -Chloro-4'-fluoroacetophenone
  • 2'-chloro-4-fluoroacetophenone
  • α-chloro-4-fluoroacetophenone
  • 2-Chloro-4′-fluoroacetophenone, CAS 456-04-2
  • 2-Chloro-4'-fluoroacetophenone
  • Ticagrelor Impurity 285
  • 456-04-2
  • FC6H4COCH2Cl
  • KETONE
  • Ketones
  • Organic Building Blocks
  • Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Acetophenone series
  • (intermediate of fluvastatin)
  • ACETYLHALIDE
  • 456-04-2