ChemicalBook > CAS DataBase List > FPL 64176

FPL 64176

Product Name
FPL 64176
CAS No.
120934-96-5
Chemical Name
FPL 64176
Synonyms
FPL 64176;ARC-64176;FPL64176, 10 mM in DMSO;MDMWHKZANMNXTF-UHFFFAOYSA-N;FPL 64176 >94% POTENT CA2+ CHANNEL (;Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate;4-(2-Benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester;2,5-Dimethyl-4-(2-benzylbenzoyl)-1H-pyrrole-3-carboxylic acid methyl ester;Ca2+ channels,FPL64176,inhibit,Inhibitor,Calcium Channel,Ca channels,FPL-64176;2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXLIC ACID METHYL ESTER
CBNumber
CB9210534
Molecular Formula
C22H21NO3
Formula Weight
347.41
MOL File
120934-96-5.mol
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FPL 64176 Property

storage temp. 
2-8°C
solubility 
DMSO: 10 mg/mL Solutions should be freshly prepared.
form 
solid
color 
tan
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F131
Product name
FPL 64176
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$380
Updated
2025/07/31
Sigma-Aldrich
Product number
F131
Product name
FPL 64176
Purity
≥98% (HPLC), powder
Packaging
100mg
Price
$1200
Updated
2023/01/07
Cayman Chemical
Product number
20122
Product name
FPL 64176
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
20122
Product name
FPL 64176
Purity
≥98%
Packaging
5mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
20122
Product name
FPL 64176
Purity
≥98%
Packaging
10mg
Price
$122
Updated
2024/03/01
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FPL 64176 Chemical Properties,Usage,Production

Uses

FPL-64176 is a nondihydropyridine Ca2+ channel activator.

Definition

ChEBI: FPL 64176 is 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group. It has a role as a calcium channel agonist. It is a member of pyrroles and a carboxylic ester.

Biological Activity

Potent activator of L-type Ca 2+ channels (EC 50 = 16 nM). 40-fold more potent than Bay K 8644 (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ) as a positive inotrope in guinea pig atria.

Biochem/physiol Actions

Potent Ca2+ channel (L-type) activator.

storage

Store at RT

FPL 64176 Preparation Products And Raw materials

Raw materials

Preparation Products

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FPL 64176 Suppliers

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120934-96-5, FPL 64176Related Search:

Gabapentin Flunarizine dihydrochloride Isradipine Cilnidipine Ryanodine Nimodipine CHARYBDOTOXIN Nicardipine hydrochloride DOTARIZINE (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride Nifedipine OMEGA-AGATOXIN TK Niguldipine (hydrochloride) 3-Acetyl-2,4-dimethylpyrrole Pyrrole-3-carboxylic acid Pyrrole-3-carboxylic acid METHYL 4-ACETYL-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE FPL 64176

  • FPL 64176
  • 2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXLIC ACID METHYL ESTER
  • 2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXYLIC ACID METHYL ESTER
  • 2,5-Dimethyl-4-(2-benzylbenzoyl)-1H-pyrrole-3-carboxylic acid methyl ester
  • 4-(2-Benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester
  • MDMWHKZANMNXTF-UHFFFAOYSA-N
  • FPL 64176 >94% POTENT CA2+ CHANNEL (
  • ARC-64176
  • 1H-Pyrrole-3-carboxylic acid, 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-, methyl ester
  • Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate
  • Ca2+ channels,FPL64176,inhibit,Inhibitor,Calcium Channel,Ca channels,FPL-64176
  • FPL64176, 10 mM in DMSO
  • 120934-96-5
  • BioChemical
  • Calcium Channel Modulators
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Inhibitors and Activators
  • Ion Channels
  • Voltage-gated Ion Channels
  • Calcium channel