FPL 64176

Product Name: FPL 64176
CAS No.: 120934-96-5
Chemical Name: FPL 64176
Synonyms: FPL 64176;ARC-64176;MDMWHKZANMNXTF-UHFFFAOYSA-N;FPL 64176 >94% POTENT CA2+ CHANNEL (;Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate;4-(2-Benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester;2,5-Dimethyl-4-(2-benzylbenzoyl)-1H-pyrrole-3-carboxylic acid methyl ester;Ca2+ channels,FPL64176,inhibit,Inhibitor,Calcium Channel,Ca channels,FPL-64176;2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXLIC ACID METHYL ESTER;2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXYLIC ACID METHYL ESTER
CBNumber: CB9210534
Molecular Formula: C22H21NO3
Formula Weight: 347.41
MOL File: 120934-96-5.mol

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FPL 64176 Property

storage temp.: 2-8°C
solubility: DMSO: 10 mg/mL Solutions should be freshly prepared.
form: solid
color: tan

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F131
Product name: FPL 64176
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $222
Updated: 2024/03/01

Sigma-Aldrich

Product number: F131
Product name: FPL 64176
Purity: ≥98% (HPLC), powder
Packaging: 100mg
Price: $1200
Updated: 2023/01/07

Cayman Chemical

Product number: 20122
Product name: FPL 64176
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 20122
Product name: FPL 64176
Purity: ≥98%
Packaging: 5mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 20122
Product name: FPL 64176
Purity: ≥98%
Packaging: 10mg
Price: $122
Updated: 2024/03/01

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FPL 64176 Chemical Properties,Usage,Production

Uses

FPL-64176 is a nondihydropyridine Ca2+ channel activator.

Definition

ChEBI: FPL 64176 is 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group. It has a role as a calcium channel agonist. It is a member of pyrroles and a carboxylic ester.

Biological Activity

Potent activator of L-type Ca 2+ channels (EC 50 = 16 nM). 40-fold more potent than Bay K 8644 (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ) as a positive inotrope in guinea pig atria.

Biochem/physiol Actions

Potent Ca2+ channel (L-type) activator.

storage

Store at RT

FPL 64176 Preparation Products And Raw materials

Raw materials

Preparation Products

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FPL 64176 Suppliers

China 43 Europe 1 Germany 3 India 1 Switzerland 3 United Kingdom 1 United States 9 Global 61

120934-96-5, FPL 64176Related Search:

Gabapentin Flunarizine dihydrochloride Isradipine Cilnidipine Ryanodine Nimodipine CHARYBDOTOXIN Nicardipine hydrochloride DOTARIZINE (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride Nifedipine OMEGA-AGATOXIN TK Niguldipine (hydrochloride) 3-Acetyl-2,4-dimethylpyrrole Pyrrole-3-carboxylic acid Pyrrole-3-carboxylic acid METHYL 4-ACETYL-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLATE FPL 64176

FPL 64176

2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXLIC ACID METHYL ESTER

2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXYLIC ACID METHYL ESTER

2,5-Dimethyl-4-(2-benzylbenzoyl)-1H-pyrrole-3-carboxylic acid methyl ester

4-(2-Benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester

MDMWHKZANMNXTF-UHFFFAOYSA-N

FPL 64176 >94% POTENT CA2+ CHANNEL (

ARC-64176

1H-Pyrrole-3-carboxylic acid, 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-, methyl ester

Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate

Ca2+ channels,FPL64176,inhibit,Inhibitor,Calcium Channel,Ca channels,FPL-64176

120934-96-5

BioChemical

Calcium Channel Modulators

Cell Biology

Cell Signaling and Neuroscience

Inhibitors and Activators

Ion Channels

Voltage-gated Ion Channels

Calcium channel