ChemicalBook > CAS DataBase List > MMP-2/MMP-9 INHIBITOR IV

MMP-2/MMP-9 INHIBITOR IV

Product Name
MMP-2/MMP-9 INHIBITOR IV
CAS No.
292605-14-2
Chemical Name
MMP-2/MMP-9 INHIBITOR IV
Synonyms
CS-860;SB-3CT;SB−MMP-2/MMP-9 INHIBITOR IV;MMP-2/MMP-9 INHIBITITOR IV;SB-3CT, MMP-2 and MMP-9 inhibitor;[[(4-Phenoxyphenyl)sulfonyl]methyl]thiirane;2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane;Thiirane, [[(4-phenoxyphenyl)sulfonyl]methyl]-;Thiirane, 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-
CBNumber
CB9223336
Molecular Formula
C15H14O3S2
Formula Weight
306.4
MOL File
292605-14-2.mol
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MMP-2/MMP-9 INHIBITOR IV Property

Melting point:
92-96°C
Boiling point:
501.4±46.0 °C(Predicted)
Density 
1.329±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: >20mg/mL
form 
powder
color 
white to off-white
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S1326
Product name
SB?3CT
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$354
Updated
2024/03/01
Sigma-Aldrich
Product number
444274
Product name
MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem
Packaging
500μg
Price
$216
Updated
2024/03/01
Cayman Chemical
Product number
16337
Product name
SB-3CT
Purity
≥95%
Packaging
500μg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
16337
Product name
SB-3CT
Purity
≥95%
Packaging
1mg
Price
$62
Updated
2024/03/01
Sigma-Aldrich
Product number
S1326
Product name
SB?3CT
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$1430
Updated
2024/03/01
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MMP-2/MMP-9 INHIBITOR IV Chemical Properties,Usage,Production

Uses

SB 3CT is a selective and potent gelatinase inhibitor which may be used for the treatment of brain metastasis.

Uses

SB?3CT has been used as irreversible inhibitor of matrix metallopeptidase 9 (MMP9) in cell cultures to exclude reciprocal regulation.

Definition

ChEBI: 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane is an aromatic ether.

Biochem/physiol Actions

SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. In particular, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis. SB-3CT exhibits a covalent mechanism based behavior in inhibition of MMP-2 and MMP-9. This inhibitor appears to have similarity to TIMP-1 and TIMP-2 in the slow-binding component of inhibition. SB-3CT has been shown to directly bind to the zinc in the catalytic site of MMP-2. SB-3CT does not affect the activities of MMP-1 (Ki = 206 μM) MMP-3 (Ki = 15 μM), or MMP-7 (Ki = 96 μM).

storage

Store at -20°C

MMP-2/MMP-9 INHIBITOR IV Preparation Products And Raw materials

Raw materials

Preparation Products

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MMP-2/MMP-9 INHIBITOR IV Suppliers

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View Lastest Price from MMP-2/MMP-9 INHIBITOR IV manufacturers

Career Henan Chemical Co
Product
2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane 292605-14-2
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-01

292605-14-2, MMP-2/MMP-9 INHIBITOR IVRelated Search:

SB-705498 SB 203580 SB242235 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride Ispinesib ISOBAVACHALCONE MCA-LYS-PRO-LEU-GLY-LEU-DAP(DNP)-ALA-ARG-NH2 Doxycycline hyclate Gefitinib Maraviroc SB 431542 Trametinib ICG-001 Ilomastat 4'-CHLORO-3-METHOXYCINNAMANILIDE 6-[2-tert-Butyl-5-(6-methyl-pyridin-2-yl)-1H-imidazol-4-yl]-quinoxaline SB1317 SB 269970 HYDROCHLORIDE

  • SB-3CT
  • MMP-2/MMP-9 INHIBITITOR IV
  • MMP-2/MMP-9 INHIBITOR IV
  • 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane
  • [[(4-Phenoxyphenyl)sulfonyl]methyl]thiirane
  • SB-3CT (This product is only available in Japan.)
  • CS-860
  • MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem
  • Thiirane, [[(4-phenoxyphenyl)sulfonyl]methyl]-
  • Thiirane, 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-
  • SB&minus
  • SB-3CT, MMP-2 and MMP-9 inhibitor
  • 292605-14-2
  • 2922605-14-2
  • Inhibitors