MMP-2/MMP-9 INHIBITOR IV
- Product Name
- MMP-2/MMP-9 INHIBITOR IV
- CAS No.
- 292605-14-2
- Chemical Name
- MMP-2/MMP-9 INHIBITOR IV
- Synonyms
- CS-860;SB-3CT;SB−MMP-2/MMP-9 INHIBITOR IV;MMP-2/MMP-9 INHIBITITOR IV;[[(4-Phenoxyphenyl)sulfonyl]methyl]thiirane;2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane;Thiirane, [[(4-phenoxyphenyl)sulfonyl]methyl]-;Thiirane, 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-;SB-3CT (This product is only available in Japan.)
- CBNumber
- CB9223336
- Molecular Formula
- C15H14O3S2
- Formula Weight
- 306.4
- MOL File
- 292605-14-2.mol
MMP-2/MMP-9 INHIBITOR IV Property
- Melting point:
- 92-96°C
- Boiling point:
- 501.4±46.0 °C(Predicted)
- Density
- 1.329±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: >20mg/mL
- form
- powder
- color
- white to off-white
N-Bromosuccinimide Price
- Product number
- S1326
- Product name
- SB?3CT
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $354
- Updated
- 2024/03/01
- Product number
- 444274
- Product name
- MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem
- Packaging
- 500μg
- Price
- $216
- Updated
- 2024/03/01
- Product number
- 16337
- Product name
- SB-3CT
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 16337
- Product name
- SB-3CT
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- S1326
- Product name
- SB?3CT
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $1430
- Updated
- 2024/03/01
MMP-2/MMP-9 INHIBITOR IV Chemical Properties,Usage,Production
Uses
SB 3CT is a selective and potent gelatinase inhibitor which may be used for the treatment of brain metastasis.
Uses
SB?3CT has been used as irreversible inhibitor of matrix metallopeptidase 9 (MMP9) in cell cultures to exclude reciprocal regulation.
Definition
ChEBI: 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane is an aromatic ether.
Biochem/physiol Actions
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. In particular, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis. SB-3CT exhibits a covalent mechanism based behavior in inhibition of MMP-2 and MMP-9. This inhibitor appears to have similarity to TIMP-1 and TIMP-2 in the slow-binding component of inhibition. SB-3CT has been shown to directly bind to the zinc in the catalytic site of MMP-2. SB-3CT does not affect the activities of MMP-1 (Ki = 206 μM) MMP-3 (Ki = 15 μM), or MMP-7 (Ki = 96 μM).
storage
Store at -20°C
MMP-2/MMP-9 INHIBITOR IV Preparation Products And Raw materials
Raw materials
Preparation Products
MMP-2/MMP-9 INHIBITOR IV Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28398
- Advantage
- 80
View Lastest Price from MMP-2/MMP-9 INHIBITOR IV manufacturers
- Product
- 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane 292605-14-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-01-01