ChemicalBook > CAS DataBase List > (R)-(+)-Lactamide

(R)-(+)-Lactamide

Product Name
(R)-(+)-Lactamide
CAS No.
598-81-2
Chemical Name
(R)-(+)-Lactamide
Synonyms
D-Lactamide;(R)-(+)-LACTAMIDE;(R)-(+)-Lactamide>(R)-(+)-Lactamide 97%;(R)-(+)-Lactamide;(R)-2-hydroxypropanamide;(2R)-2-Hydroxypropanamide;(R)-(+)-2-HYDROXYPROPIONAMIDE;Propanamide, 2-hydroxy-, (2R)-;(R)-(+)-Lactamide, 98%, ee: 99%
CBNumber
CB9237504
Molecular Formula
C3H7NO2
Formula Weight
89.09
MOL File
598-81-2.mol
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(R)-(+)-Lactamide Property

Melting point:
50-53 °C(lit.)
alpha 
21 º (C=10 IN H2O)
Boiling point:
281.9±23.0 °C(Predicted)
Density 
1.161±0.06 g/cm3(Predicted)
refractive index 
20.5 ° (C=10, H2O)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to crystal
pka
13.34±0.20(Predicted)
color 
White to Light yellow to Light orange
optical activity
[α]20/D +21.0°, c = 10 in H2O
InChI
InChI=1S/C3H7NO2/c1-2(5)3(4)6/h2,5H,1H3,(H2,4,6)/t2-/m1/s1
InChIKey
SXQFCVDSOLSHOQ-UWTATZPHSA-N
SMILES
C(N)(=O)[C@H](O)C
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25-36/37/38
Safety Statements 
24/25-45-36/37/39-26
WGK Germany 
3
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
436801
Product name
(R)-(+)-Lactamide
Purity
97%
Packaging
10g
Price
$202
Updated
2023/01/07
TCI Chemical
Product number
L0167
Product name
(R)-(+)-Lactamide
Purity
>98.0%(GC)(N)
Packaging
5g
Price
$70
Updated
2025/07/31
TCI Chemical
Product number
L0167
Product name
(R)-(+)-Lactamide
Purity
>98.0%(GC)(N)
Packaging
25g
Price
$242
Updated
2025/07/31
TRC
Product number
L101038
Product name
(R)-(+)-Lactamide
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
L101038
Product name
(R)-(+)-Lactamide
Packaging
500mg
Price
$75
Updated
2021/12/16
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(R)-(+)-Lactamide Chemical Properties,Usage,Production

Definition

ChEBI: (R)-(+)-Lactamide is a carboxamide.

Synthesis

547-64-8

598-81-2

GENERAL METHOD: α-Hydroxymethyl ester (10 mmol, 1.0 eq.) was placed in a 100 mL round-bottom flask (RBF) and saturated ammonia solution (20 mL, 38 eq.) was slowly added under ice-water bath conditions, followed by stirring the reaction mixture overnight. Upon completion of the reaction, the solvent is removed by concentration under reduced pressure, and in most cases, high purity (R)-2-hydroxypropionamide can be obtained directly in high yield. If the product is not of sufficient purity, it can be purified by fast column chromatography (silica gel 200-300 mesh, eluent ratio dichloromethane: methanol = 15:1).

References

[1] Chemistry Letters, 2017, vol. 46, # 2, p. 249 - 252

(R)-(+)-Lactamide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-(+)-Lactamide manufacturers

Career Henan Chemical Co
Product
(R)-(+)-Lactamide 598-81-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-31

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