VU 0357017 hydrochloride

Product Name: VU 0357017 hydrochloride
CAS No.: 1135242-13-5
Chemical Name: VU 0357017 hydrochloride
Synonyms: CS-2319;VU0357017;CID 25010775;SID 56353039;VU0357017 HCI;ML071 hydrochloride;VU 0357017 hydrochloride;VU0357017 monohydrochloride;Ethyl 4-(2-(2-methylbenzamido)ethylamino)piperidine-1-carboxylate hydrochloride;VU0-357017;VU 0357017;CID-25010775; VU-0357017 HYDROCHLORIDE; VU 0357017 HYDROCHLORIDE
CBNumber: CB92546794
Molecular Formula: C18H28ClN3O3
Formula Weight: 369.9
MOL File: 1135242-13-5.mol

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VU 0357017 hydrochloride Property

storage temp.: Inert atmosphere,2-8°C
solubility: DMSO: ≥10mg/mL
form: powder
color: white to off-white

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Safety

Hazard Codes: N
Risk Statements: 52/53
Safety Statements: 61
WGK Germany: 2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: V4640
Product name: VU0357017 monohydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $134
Updated: 2024/03/01

Sigma-Aldrich

Product number: V4640
Product name: VU0357017 monohydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $465
Updated: 2022/05/15

Cayman Chemical

Product number: 11939
Product name: VU0357017 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 11939
Product name: VU0357017 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $90
Updated: 2024/03/01

Cayman Chemical

Product number: 11939
Product name: VU0357017 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $164
Updated: 2024/03/01

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VU 0357017 hydrochloride Chemical Properties,Usage,Production

Uses

VU0357017 is a subtype-selective M1 muscarinic acetylcholine allosteric agonist. VU0357017 has a potency of 200 nM and Achmax of 81% and had no activity at M2-M5 up to the highest concentrations tested and also had little or no detectable antagonist activity at any other mAChR subtype at concentrations over 2 orders of magnitude higher than those required to activate M1 or activity at a large panel of GPCRs, ion channels, and transporters. In contrast, TBPB inhibited responses to ACh at each of the other mAChR subtypes. VU0357017 was active in reversing cognitive deficits induced by Scopolamine (S200000) in a preclinical rodent model.

Uses

VU 0357017 Hydrochloride is a cholinergic M1 receptor antagonist and a cholinomimetic agent used for the treatment of behavioral and/or mental disorders.

storage

+4°C

VU 0357017 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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VU 0357017 hydrochloride Suppliers

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1135242-13-5, VU 0357017 hydrochlorideRelated Search:

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide VU 0285683 VU0155041 VU0134992(hydrochloride) VU6005649 VU 591 hydrochloride VU0810464 VU0483605 N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin VU 6008667 (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide 5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid 4-trifluoromethanesulfonyl-benzylamide 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine VU 0360172 VU 0365114 VU 0357121 VU 0360223

VU 0357017 hydrochloride

VU0-357017;VU 0357017;CID-25010775; VU-0357017 HYDROCHLORIDE; VU 0357017 HYDROCHLORIDE

CS-2319

4-[[2-[(2-Methylbenzoyl)aMino]ethyl]aMino]-1-piperidinecarboxylic Acid Ethyl Ester Hydrochloride

4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester monohydrochloride

CID 25010775

Ethyl 4-(2-(2-methylbenzamido)ethylamino)piperidine-1-carboxylate hydrochloride

ML071 hydrochloride

SID 56353039

VU0357017 monohydrochloride

VU0357017

VU0357017 HCI

Muscarinic acetylcholine receptor,CID 25010775,VU 0357017,muscarinic,Inhibitor,inhibit,VU-0357017 hydrochloride,VU0357017 hydrochloride,VU0357017,mAChR,VU-0357017,CID25010775,acetylcholine,Alzheimer’s,schizophrenia

1135242-13-5

C18H27N3O3HCl

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Positive allosteric modulator of muscarinic M1 receptors.

Amines