ChemicalBook > CAS DataBase List > VU 0357017 hydrochloride
VU 0357017 hydrochloride
- Product Name
- VU 0357017 hydrochloride
- CAS No.
- 1135242-13-5
- Chemical Name
- VU 0357017 hydrochloride
- Synonyms
- CS-2319;VU0357017;CID 25010775;SID 56353039;VU0357017 HCI;ML071 hydrochloride;VU 0357017 hydrochloride;VU0357017 monohydrochloride;Ethyl 4-(2-(2-methylbenzamido)ethylamino)piperidine-1-carboxylate hydrochloride;VU0-357017;VU 0357017;CID-25010775; VU-0357017 HYDROCHLORIDE; VU 0357017 HYDROCHLORIDE
- CBNumber
- CB92546794
- Molecular Formula
- C18H28ClN3O3
- Formula Weight
- 369.9
- MOL File
- 1135242-13-5.mol
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VU 0357017 hydrochloride Property
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO: ≥10mg/mL
- form
- powder
- color
- white to off-white
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- V4640
- Product name
- VU0357017 monohydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $134
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- V4640
- Product name
- VU0357017 monohydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $465
- Updated
- 2022/05/15
Cayman Chemical
- Product number
- 11939
- Product name
- VU0357017 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $33
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 11939
- Product name
- VU0357017 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $90
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 11939
- Product name
- VU0357017 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $164
- Updated
- 2024/03/01
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VU 0357017 hydrochloride Chemical Properties,Usage,Production
Uses
VU0357017 is a subtype-selective M1 muscarinic acetylcholine allosteric agonist. VU0357017 has a potency of 200 nM and Achmax of 81% and had no activity at M2-M5 up to the highest concentrations tested and also had little or no detectable antagonist activity at any other mAChR subtype at concentrations over 2 orders of magnitude higher than those required to activate M1 or activity at a large panel of GPCRs, ion channels, and transporters. In contrast, TBPB inhibited responses to ACh at each of the other mAChR subtypes. VU0357017 was active in reversing cognitive deficits induced by Scopolamine (S200000) in a preclinical rodent model.
Uses
VU 0357017 Hydrochloride is a cholinergic M1 receptor antagonist and a cholinomimetic agent used for the treatment of behavioral and/or mental disorders.
storage
+4°C
VU 0357017 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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VU 0357017 hydrochloride Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77
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