CTOP

Product Name: CTOP
CAS No.: 103429-31-8
Chemical Name: CTOP
Synonyms: NTB;CTOP;NALTRIBEN;threoninamide;CYS2,TYR3,ORN5,PEN7-AMIDE;M.W. 1062.26 C50H67N11O11S2;(Tyr3,Orn5,Pen7)-Octreotate amide;Cys2, Tyr3, Orn5, Pen7 amide - CTOP;DPHE-CYS-TYR-DTRP-ORN-THR-PEN-THR-OL;D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2
CBNumber: CB9260913
Molecular Formula: C50H67N11O11S2
Formula Weight: 1062.26
MOL File: 103429-31-8.mol

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CTOP Property

Boiling point:: 1491.2±65.0 °C(Predicted)
Density: 1.42±0.1 g/cm3(Predicted)
RTECS: XO8578200
storage temp.: -20°C
pka: 9.90±0.15(Predicted)
form: Powder
Water Solubility: Soluble to 1 mg/ml in water

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P5296
Product name: CTOP
Purity: ≥97% (HPLC)
Packaging: 1mg
Price: $274
Updated: 2024/03/01

Alfa Aesar

Product number: J66263
Product name: CTOP
Packaging: 1mg
Price: $122
Updated: 2021/12/16

Alfa Aesar

Product number: J66263
Product name: CTOP
Packaging: 5mg
Price: $441
Updated: 2021/12/16

Tocris

Product number: 1578
Product name: CTOP
Packaging: 1
Price: $195
Updated: 2021/12/16

TRC

Product number: C800010
Product name: CTOP
Packaging: 1mg
Price: $195
Updated: 2021/12/16

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CTOP Chemical Properties,Usage,Production

Uses

CTOP is a μ-opioid receptor antagonist which has been shown to regulate behaviour and expression in rats. An endogenous opioid peptide which may also be used in the treatment of pain through improved morphine tolerance via blocking of mTOR.

Uses

CTOP has been used:

to study the anxiogenic effects induced by CTOP in mice and rat.
to study the effect of μ-opioid antagonist, CTOP on the bovine milk-derived LF (BLF)-induced analgesia.
to determine whether μ-opioid receptors act cooperatively with 5-hydroxytryptamine (5-HT1A) receptors to regulate the behaviors generated in the elevated T-maze (ETM).

General Description

D-Pen-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) is a selective cyclic μ-opioid receptor antagonist.

Biochem/physiol Actions

Selective ligand for μ-opioid receptors.

storage

Store at -20°C

CTOP Preparation Products And Raw materials

Raw materials

Preparation Products

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CTOP Suppliers

China 76 Europe 1 France 1 Germany 2 Switzerland 1 United Kingdom 2 United States 13 Global 96

Service Chemical Inc.

Tel: --
Fax: --
Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

BIOTREND Chemicals AG

Tel: --
Fax: --
Email: info@biotrend.ch
Country: Germany
ProdList: 1250
Advantage: 62

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View Lastest Price from CTOP manufacturers

Career Henan Chemical Co

Product: CTOP 103429-31-8
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-11

103429-31-8, CTOPRelated Search:

L-Threoninamide monohydrochloride ,L-Threoninamide HCl,L-THREONINAMIDE HYDROCHLORIDE 3-(2-Naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide cyclic (2-7)-disulfide N-Carbobenzyloxy-L-threoninamide,N2-(Benzyloxycarbonyl)-L-threoninamide,Z-L-THREONINAMIDE,N-Benzyloxycarbonyl-L-Threoninamide,CBZ-L-THREONINAMIDE isopropyl methyl disulphide L-Penicillamine Z-L-THREONINAMIDE,CBZ-L-THREONINAMIDE CTAP CTOP L-Threoninamide, D-phenylalanyl-L-cycteingyl-L-phenylalanyl-D-tryptoph yl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2-7)-disulfide L-Threoninamide n-acetyl-n-methyl-l-isoleucyl-l-isoleucyl-n-[(1s)-3-methyl-1-[[(2r)-2-methyloxiranyl]carbonyl]butyl]-l-threoninamide technetium Tc 99m dioxo-1-(alanyl-seryl-threonyl-theonyl-threonyl-asparaginyl-tyrosyl-threoninamide)cyclam phenylalanyl--cysteinyl-tyrosyl-tryptophyl-arginyl-penicillaminyl-threoninamide N-Hydroxy-L-threoninamide phenylalanyl-chlorophenylalanyl-tyrosyl-tryptophyl-lysyl-valyl-phenylalanyl-threoninamide 2-naphthylalanyl-cyclo(cysteinyl-tyrosyl-tryptophyl-lysyl-valyl-cysteinyl)-threoninamide isopropyl propyl disulphide N-octanoyl-asparaginyl-tyrosyl-threoninamide

threoninamide

NALTRIBEN

NTB

D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR AMIDE

D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2

DPHE-CYS-TYR-DTRP-ORN-THR-PEN-THR-OL

CTOP

CYS2,TYR3,ORN5,PEN7-AMIDE

[CYS2, TYR3, ORN5, PEN7]-SOMATOSTATIN 14 (7-14), AMIDE

H-D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2

H-D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 (DISULFIDE BRIDGE: 2-7)

FCYW(ORN)T(PEN)T-NH2 (DISULFIDE BRIDGE: 2-7)

phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide

H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2, (Disulfide bond between Cys2 and Pen7)

M.W. 1062.26 C50H67N11O11S2

D-Phe-L-Cys(1)-L-Tyr-D-Trp-L-Orn-L-Thr-3-Mercapto(1)-L-Val-L-Thr-NH2

D-Phe-L-Cys(1)-L-Tyr-D-Trp-L-Orn-L-Thr-L-Pen(1)-L-Thr-NH2

[Cys2, Tyr3, Orn5, Pen7-amide]-Somatostatin 14 (7-14)

Cys2, Tyr3, Orn5, Pen7 amide - CTOP

CTOP, (Tyr3,Orn5,Pen7)-Octreotate aMide

(Tyr3,Orn5,Pen7)-Octreotate amide

phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)

H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (Disulfide bond)

L-Threoninamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-, cyclic (2→7)-disulfide

Cys2, Tyr3, Orn5, Pen7-NH2]-Somatostatin14(7-14)

H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (Disulfide bond) TFA Salt

103429-31-8

C50H67N11O11S2

Opioid Peptides

Other Opioid Peptides

Peptides

BioChemical

Biochemicals and Reagents

Amino Acids and Peptides

peptide

Neuropeptides

Opioid Peptides

Other Opioid Peptides

Other Opioid PeptidesPeptides for Cell Biology

Opioid receptor and opioid-like receptor