ETHYL 2-METHYL-5-NITRONICOTINATE
- Product Name
- ETHYL 2-METHYL-5-NITRONICOTINATE
- CAS No.
- 51984-71-5
- Chemical Name
- ETHYL 2-METHYL-5-NITRONICOTINATE
- Synonyms
- ETHYL 2-METHYL-5-NITRONICOTITE;ETHYL 2-METHYL-5-NITRONICOTINATE;2-Methyl-5-nitro-nicotinic acid ethyl ester;ethyl 2-Methyl-5-nitropyridine-3-carboxylate;Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate;Pyridinecarboxylicacid,2-Methyl-5-nitro-,ethylester;3-Pyridinecarboxylicacid, 2-Methyl-5-nitro-, ethyl ester
- CBNumber
- CB9263479
- Molecular Formula
- C9H10N2O4
- Formula Weight
- 210.19
- MOL File
- 51984-71-5.mol
ETHYL 2-METHYL-5-NITRONICOTINATE Property
- Melting point:
- 64-65 °C
- Boiling point:
- 309.6±37.0 °C(Predicted)
- Density
- 1.272±0.06 g/cm3(Predicted)
- storage temp.
- Store at room temperature
- pka
- -0.02±0.20(Predicted)
- Appearance
- White to yellow Solid
N-Bromosuccinimide Price
- Product number
- CS-W000714
- Product name
- Ethyl2-methyl-5-nitro-3-pyridinecarboxylate
- Purity
- 99.53%
- Packaging
- 1g
- Price
- $69
- Updated
- 2021/12/16
- Product number
- 072202
- Product name
- Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $231
- Updated
- 2021/12/16
- Product number
- W6681
- Product name
- Ethyl2-methyl-5-nitro-3-pyridinecarboxylate
- Packaging
- 5g
- Price
- $436
- Updated
- 2021/12/16
- Product number
- 072202
- Product name
- Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $500
- Updated
- 2021/12/16
- Product number
- CHM0094489
- Product name
- 2-METHYL-5-NITRO-NICOTINIC ACID ETHYL ESTER
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $852.55
- Updated
- 2021/12/16
ETHYL 2-METHYL-5-NITRONICOTINATE Chemical Properties,Usage,Production
Synthesis
609-32-5
626-34-6
51984-71-5
General procedure for the synthesis of ethyl 2-methyl-5-nitronicotinate from nitromalonaldehyde and ethyl 3-aminocrotonate: nitromalonaldehyde (416 g, 3.6 mol) and ethyl 3-aminocrotonate (339 g, 2.6 mol) were added to a solvent mixture consisting of ethanol (1.9 L), water (1.9 L) and glacial acetic acid (240 mL). The reaction mixture was stirred and reacted at 50 °C overnight. Upon completion of the reaction, the reaction solution was concentrated by distillation under reduced pressure. The concentrated residue was dissolved in dichloromethane (5.0 L) and filtered to remove insoluble matter. The filtrate was concentrated and purified by column chromatography (eluent ratio: ethyl acetate:petroleum ether = 1:10) to afford the target product ethyl 2-methyl-5-nitronicotinate (165 g, 30% yield) as a white solid. The product was characterized by 1H NMR (CDCl3, 300 MHz): δ= 1.23-1.26 (t, 3H), 2.25 (s, 3H), 4.14-4.21 (q, 2H), 8.91-8.92 (t, 1H), 9.37-9.38 (d, 1H).LC-MS analysis showed that the [M + 1]+ peak was located at 210.2.
References
[1] Patent: WO2008/88881, 2008, A1. Location in patent: Page/Page column 33-34
ETHYL 2-METHYL-5-NITRONICOTINATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ETHYL 2-METHYL-5-NITRONICOTINATE manufacturers
- Product
- ETHYL 2-METHYL-5-NITRONICOTINATE 51984-71-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-18
- Product
- ETHYL 2-METHYL-5-NITRONICOTINATE 51984-71-5
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%MIN
- Supply Ability
- ASK
- Release date
- 2019-12-25