Hyperforin . DCHA

Product Name: Hyperforin . DCHA
CAS No.: 238074-03-8
Chemical Name: Hyperforin . DCHA
Synonyms: Hyp-DCHA;C47H75NO4;Hyperforin . DCHA;Hyperforin (dicylcohexylammonium) salt;Hyperforin (stable Dicyclohexylammonium salt);Hyperforin / AdhyperforinDicyclohexylammonium salt (4:1);Hyperforin (dicyclohexylammonium) salt analytical standard;N-cyclohexylcyclohexanamine,(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione
CBNumber: CB92650749
Molecular Formula: C47H75NO4
Formula Weight: 718.12
MOL File: 238074-03-8.mol

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Hyperforin . DCHA Property

storage temp.: -20°C
solubility: DMSO: ≥10mg/mL
form: powder
color: white to off-white

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Safety

Hazard Codes: C,N
Risk Statements: 22-34-50/53
Safety Statements: 26-36/37/39-45-60-61
RIDADR: UN 1759 8 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H400Very toxic to aquatic life

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H1792
Product name: Hyperforin (dicyclohexylammonium) salt
Packaging: 1mg
Price: $353
Updated: 2024/03/01

Sigma-Aldrich

Product number: 42891
Product name: Hyperforin (dicyclohexylammonium) salt
Purity: analytical standard
Packaging: 5mg
Price: $570
Updated: 2022/05/15

Cayman Chemical

Product number: 19572
Product name: Hyperforin (dicyclohexylammonium salt)
Purity: ≥97%
Packaging: 500μg
Price: $134
Updated: 2024/03/01

Cayman Chemical

Product number: 19572
Product name: Hyperforin (dicyclohexylammonium salt)
Purity: ≥97%
Packaging: 1mg
Price: $201
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL89225
Product name: Hyperforin (stable Dicyclohexylammonium salt)
Purity: phyproof? Reference Substance
Packaging: 10mg
Price: $1000
Updated: 2024/03/01

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Hyperforin . DCHA Chemical Properties,Usage,Production

Description

Hyperforin is a natural activator of the steroid X receptor (active at 0.1 to 0.5 μg/ml) and inhibitor of several cytochrome P450 (CYP) isoforms (IC₅₀ = 10 μg/ml for CYP2D6). It can also inhibit microsomal prostaglandin E₂ synthase-1 (mPGES-1; IC₅₀ = 1 μM), 5-lipoxygenase activating protein, and sirtuins.

Uses

Hyperforin Dicyclohexylammonium Salt is an inhibitor of monoamine uptake and TRPC6 agonist.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Stable salt of hyperforin. Hyperforin is believed to be the primary active constituent responsible for the antidepressant and anxiolytic properties of the extracts of St. John′s wort. It acts as a reuptake inhibitor of monoamines, including serotonin, norepinephrine, dopamine, and of GABA and glutamate by activating the transient receptor potential ion channel TRPC6. Activation of TRPC6 induces the entry of sodium and calcium into the cell which causes inhibition of monoamine reuptake. It also is an activator of the pregnane X receptor (PXR), which serves as a key regulator of CYP3A4 transcription, a member of the cytochrome (CYP) P450 enzyme system. Recent studies have found other neurological effects, effects on inflammation, as well as antibacterial, antitumoral and antiangiogenic effects.

storage

+4°C

Hyperforin . DCHA Preparation Products And Raw materials

Raw materials

Preparation Products

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Hyperforin . DCHA Suppliers

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Hyp-DCHA

Hyperforin (stable Dicyclohexylammonium salt)

Hyperforin . DCHA

C47H75NO4

Hyperforin / AdhyperforinDicyclohexylammonium salt (4:1)

Hyperforin (dicylcohexylammonium) salt

Hyperforin (dicyclohexylammonium) salt analytical standard

N-cyclohexylcyclohexanamine,(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione

238074-03-8

C35H52O4C12H23N