GS9620

Product Name: GS9620
CAS No.: 1228585-88-3
Chemical Name: GS9620
Synonyms: Gs-20;CS-925;GS9620;GS-9620;GS 9620;Vesatolimod;GS9620, >=98%;GS 9620; GS9620;GS-9620(Vesatolimod);Vesatolimod GS-9620
CBNumber: CB92666623
Molecular Formula: C22H30N6O2
Formula Weight: 410.51
MOL File: 1228585-88-3.mol

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GS9620 Property

Density: 1.247±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO (10 mg/ml)
form: solid
pka: 10.34±0.20(Predicted)
color: Off-white
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19628
Product name: GS-9620
Purity: ≥98%
Packaging: 5mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 19628
Product name: GS-9620
Purity: ≥98%
Packaging: 10mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 19628
Product name: GS-9620
Purity: ≥98%
Packaging: 25mg
Price: $180
Updated: 2024/03/01

Cayman Chemical

Product number: 19628
Product name: GS-9620
Purity: ≥98%
Packaging: 100mg
Price: $477
Updated: 2024/03/01

ApexBio Technology

Product number: A3444
Product name: GS-9620
Packaging: 50mg
Price: $700
Updated: 2021/12/16

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GS9620 Chemical Properties,Usage,Production

Description

GS-9620 is a potent and selective oral Toll-like receptor 7 (TLR7) agonist that directly activates plasmacytoid dendritic cells (pDCs). GS-9620 suppressed hepatitis B virus (HBV) in animal models of chronic infection and transiently activated HIV expressionex vivoin latently-infected peripheral blood mononuclear cells (PBMCs) from virally suppressed patients. Currently, GS-9620 is under clinical evaluation for treating chronic HBV infection and for reducing latent reservoirs in virally-suppressed HIV-infected patients.

target

TLR-7

References

Lopatin, U, et al. "Safety, pharmacokinetics and pharmacodynamics of GS-9620, an oral Toll-like receptor 7 agonist." Antiviral Therapy18.3(2013):409-18.
Gane, E. J., et al. "The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection." Journal of Hepatology63.2(2015):320.
Lanford, Robert E., et al. "GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees." Gastroenterology 144.7(2013):1508.

GS9620 Preparation Products And Raw materials

Raw materials

Preparation Products

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GS9620 Suppliers

China 105 India 1 United Kingdom 1 United States 15 Global 122

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

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View Lastest Price from GS9620 manufacturers

Anhui Ruihan Technology Co., Ltd

Product: GS9620 1228585-88-3
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2023-09-07

Career Henan Chemical Co

Product: GS9620 1228585-88-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2019-08-07

1228585-88-3, GS9620Related Search:

3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide Levetiracetam Elafibranor(GFT505) BI 2536 Hydrochloride Entospletinib (GS-9973) GSK2643943A GS967 GSK J1 GSK-114 GSK-626616 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Selonsertib Presatovir 4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE Ribonucleic acid IXABEPILONE GSK163090

CS-925

GS 9620; GS9620

Vesatolimod

GS9620, >=98%

4-amino-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one

4-amino-2-butoxy-8-(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one

4-Amino-2-butoxy-8-[3-(1-pyrrolidinylmethyl)benzyl]-7,8-dihydro-6(5H)-pteridinone

GS 9620

GS9620

GS-9620

4-Amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-6(5H)-pteridinone

8-(3-(pyrrolidin-1-ylMethyl)benzyl)-4-aMino-2-butoxy-7,8-dihydropteridin-6(5H)-one

MFCD25372045 (GS-9620)

4-Amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-6(5H)-pteridinone GS 9620

6(5H)-Pteridinone, 4-amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl] HCl

Vesatolimod GS-9620

6(5H)-Pteridinone, 4-amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-

Gs-20

GS-9620(Vesatolimod)

4-amino-2-butoxy-8-Chemicalbook(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one

GS-9620 Vesatolimod GS9620

1228585-88-3

12285885-88-3

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