GS9620

Product Name: GS9620
CAS No.: 1228585-88-3
Chemical Name: GS9620
Synonyms: Gs-20;CS-925;GS9620;GS-9620;GS 9620;Vesatolimod;GS9620, >=98%;GS 9620; GS9620;GS-9620(Vesatolimod);Vesatolimod GS-9620
CBNumber: CB92666623
Molecular Formula: C22H30N6O2
Formula Weight: 410.51
MOL File: 1228585-88-3.mol

More

Less

GS9620 Property

Density: 1.247±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO (10 mg/ml)
form: solid
pka: 10.34±0.20(Predicted)
color: Off-white
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 19628
Product name: GS-9620
Purity: ≥98%
Packaging: 5mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 19628
Product name: GS-9620
Purity: ≥98%
Packaging: 10mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 19628
Product name: GS-9620
Purity: ≥98%
Packaging: 25mg
Price: $180
Updated: 2024/03/01

Cayman Chemical

Product number: 19628
Product name: GS-9620
Purity: ≥98%
Packaging: 100mg
Price: $477
Updated: 2024/03/01

ApexBio Technology

Product number: A3444
Product name: GS-9620
Packaging: 50mg
Price: $700
Updated: 2021/12/16

More

Less

GS9620 Chemical Properties,Usage,Production

Description

GS-9620 is a potent and selective oral Toll-like receptor 7 (TLR7) agonist that directly activates plasmacytoid dendritic cells (pDCs). GS-9620 suppressed hepatitis B virus (HBV) in animal models of chronic infection and transiently activated HIV expressionex vivoin latently-infected peripheral blood mononuclear cells (PBMCs) from virally suppressed patients. Currently, GS-9620 is under clinical evaluation for treating chronic HBV infection and for reducing latent reservoirs in virally-suppressed HIV-infected patients.

target

TLR-7

References

Lopatin, U, et al. "Safety, pharmacokinetics and pharmacodynamics of GS-9620, an oral Toll-like receptor 7 agonist." Antiviral Therapy18.3(2013):409-18.
Gane, E. J., et al. "The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection." Journal of Hepatology63.2(2015):320.
Lanford, Robert E., et al. "GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees." Gastroenterology 144.7(2013):1508.

GS9620 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

GS9620 Suppliers

China 105 India 1 United Kingdom 1 United States 14 Global 121

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

More

Less

View Lastest Price from GS9620 manufacturers

Anhui Ruihan Technology Co., Ltd

Product: GS9620 1228585-88-3
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2023-09-07

Career Henan Chemical Co

Product: GS9620 1228585-88-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2019-08-07

1228585-88-3, GS9620Related Search:

3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide Levetiracetam Elafibranor(GFT505) BI 2536 Hydrochloride Entospletinib (GS-9973) GSK2643943A GS967 GSK J1 GSK-114 GSK-626616 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Selonsertib Presatovir 4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE Ribonucleic acid IXABEPILONE GSK163090

CS-925

GS 9620; GS9620

Vesatolimod

GS9620, >=98%

4-amino-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one

4-amino-2-butoxy-8-(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one

4-Amino-2-butoxy-8-[3-(1-pyrrolidinylmethyl)benzyl]-7,8-dihydro-6(5H)-pteridinone

GS 9620

GS9620

GS-9620

4-Amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-6(5H)-pteridinone

8-(3-(pyrrolidin-1-ylMethyl)benzyl)-4-aMino-2-butoxy-7,8-dihydropteridin-6(5H)-one

MFCD25372045 (GS-9620)

4-Amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-6(5H)-pteridinone GS 9620

6(5H)-Pteridinone, 4-amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl] HCl

Vesatolimod GS-9620

6(5H)-Pteridinone, 4-amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-

Gs-20

GS-9620(Vesatolimod)

4-amino-2-butoxy-8-Chemicalbook(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one

GS-9620 Vesatolimod GS9620

1228585-88-3

12285885-88-3

API