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Etilefrine hydrochloride

Product Name
Etilefrine hydrochloride
CAS No.
943-17-9
Chemical Name
Etilefrine hydrochloride
Synonyms
Epholin;Funasol;Efortil;Efotinon;Ehochlon;Circupon;Effontil;Effortil;Kertasin;Phetanol
CBNumber
CB9268575
Molecular Formula
C10H15NO2.ClH
Formula Weight
217.69
MOL File
943-17-9.mol
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Etilefrine hydrochloride Property

Melting point:
122 °C
storage temp. 
-20°C
solubility 
Freely soluble in water, soluble in ethanol (96 per cent), practically insoluble in methylene chloride
form 
Solid
color 
White to off-white
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Safety

RIDADR 
UN 2811 6.1 / PGIII
RTECS 
DO5618000
HS Code 
2922290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E2451000
Product name
Etilefrine hydrochloride
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
e2451000
Price
$153
Updated
2024/03/01
TRC
Product number
E932950
Product name
EtilefrinHydrochloride
Packaging
1g
Price
$400
Updated
2021/12/16
TRC
Product number
E932950
Product name
EtilefrinHydrochloride
Packaging
5g
Price
$580
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002652
Product name
ETILEFRINE HYDROCHLORIDE
Purity
95.00%
Packaging
1G
Price
$648.81
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002652
Product name
ETILEFRINE HYDROCHLORIDE
Purity
95.00%
Packaging
2.5G
Price
$852.21
Updated
2021/12/16
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Etilefrine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals.

Originator

Circupon,Troponwerke,W. Germany

Uses

Adrenoceptor agonist.

Definition

ChEBI: Etilefrine hydrochloride (TN) is a member of phenols.

Manufacturing Process

30 parts of 1-(3'-hydroxyphenyl)-2-(N-benzylaminomethyl)-ethan-1-one are mixed with 100 parts of pyridine and 30 parts of pivalic anhydride and dissolved while warming. After heating for 1 hour under reflux, the acylation is complete. After concentrating the reaction solution, the product is precipitated from acetone/ether. Yield: 96.4% of 1-(3'-pivaloyloxyphenyl)-2- (N-benzylaminomethyl)-ethan-1-one.
3 parts of palladium/charcoal (10% strength) are prehydrogenated in water, thereafter 10 parts of 1-(3'-pivaloyloxyphenyl)-2-(N-benzylaminoethyl)-ethan- 1-one, dissolved in a 10-fold amount of water, are added dropwise at room temperature and hydrogenation is carried out until 1 mol of hydrogen has been taken up. After filtering off the catalyst, a further 3 parts of palladium/charcoal are added and hydrogenation is carried out until a further mol of hydrogen has been taken up. The catalyst is separated off and after removal of the solvent the hydrogenation product is reprecipitated from acetone/petroleum ether and from methanol/ether until it is pure according to thin layer chromatography. Yield: 38.8% of 1-(3'-pivaloyloxyphenyl)-2- ethylaminoethanol-1 hydroxide, melting point 208°C to 209°C.

Therapeutic Function

Tranquilizer

Etilefrine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Etilefrine hydrochloride Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9346
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18043
Advantage
56
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
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View Lastest Price from Etilefrine hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Etilefrine hydrochloride 943-17-9
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
98%-101%; EP
Supply Ability
50kg
Release date
2021-06-02
Hebei Chuanghai Biotechnology Co,.LTD
Product
Tilefrine Hydrochloride 943-17-9
Price
US $50.00-20.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-20
Hong Kong Excellence Biotechnology Co., Ltd.
Product
Etilefrine hydrochloride 943-17-9
Price
US $100.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
20tons
Release date
2023-10-12

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