ChemicalBook > CAS DataBase List > Etilefrine hydrochloride

Etilefrine hydrochloride

Product Name: Etilefrine hydrochloride
CAS No.: 943-17-9
Chemical Name: Etilefrine hydrochloride
Synonyms: Epholin;Funasol;Efortil;Efotinon;Ehochlon;Circupon;Effontil;Effortil;Kertasin;Phetanol
CBNumber: CB9268575
Molecular Formula: C10H15NO2.ClH
Formula Weight: 217.69
MOL File: 943-17-9.mol

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Etilefrine hydrochloride Property

Melting point:: 122 °C
storage temp.: -20°C
solubility: Freely soluble in water, soluble in ethanol (96 per cent), practically insoluble in methylene chloride
form: Solid
color: White to off-white

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Safety

RIDADR: UN 2811 6.1 / PGIII
RTECS: DO5618000
HS Code: 2922290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E2451000
Product name: Etilefrine hydrochloride
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 75 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: E2451000
Product name: Etilefrine hydrochloride
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: e2451000
Price: $153
Updated: 2024/03/01

TCI Chemical

Product number: E0381
Product name: Etilefrine Hydrochloride
Packaging: 5G
Price: $118
Updated: 2025/07/31

TCI Chemical

Product number: E0381
Product name: Etilefrine Hydrochloride
Packaging: 25G
Price: $354
Updated: 2025/07/31

TRC

Product number: E932950
Product name: EtilefrinHydrochloride
Packaging: 1g
Price: $400
Updated: 2021/12/16

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Etilefrine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals.

Originator

Circupon,Troponwerke,W. Germany

Uses

Adrenoceptor agonist.

Definition

ChEBI: Etilefrine hydrochloride (TN) is a member of phenols.

Manufacturing Process

30 parts of 1-(3'-hydroxyphenyl)-2-(N-benzylaminomethyl)-ethan-1-one are mixed with 100 parts of pyridine and 30 parts of pivalic anhydride and dissolved while warming. After heating for 1 hour under reflux, the acylation is complete. After concentrating the reaction solution, the product is precipitated from acetone/ether. Yield: 96.4% of 1-(3'-pivaloyloxyphenyl)-2- (N-benzylaminomethyl)-ethan-1-one.
3 parts of palladium/charcoal (10% strength) are prehydrogenated in water, thereafter 10 parts of 1-(3'-pivaloyloxyphenyl)-2-(N-benzylaminoethyl)-ethan- 1-one, dissolved in a 10-fold amount of water, are added dropwise at room temperature and hydrogenation is carried out until 1 mol of hydrogen has been taken up. After filtering off the catalyst, a further 3 parts of palladium/charcoal are added and hydrogenation is carried out until a further mol of hydrogen has been taken up. The catalyst is separated off and after removal of the solvent the hydrogenation product is reprecipitated from acetone/petroleum ether and from methanol/ether until it is pure according to thin layer chromatography. Yield: 38.8% of 1-(3'-pivaloyloxyphenyl)-2- ethylaminoethanol-1 hydroxide, melting point 208°C to 209°C.

Therapeutic Function

Tranquilizer

Etilefrine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Etilefrine hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Etilefrine hydrochloride 943-17-9
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 98%-101%; EP
Supply Ability: 50kg
Release date: 2021-06-02

Hebei Chuanghai Biotechnology Co,.LTD

Product: Tilefrine Hydrochloride 943-17-9
Price: US $50.00-20.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-20

Shaanxi Dideu Medichem Co. Ltd

Product: Etilefrine hydrochloride 943-17-9
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2024-08-28

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943-17-9