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FMoc-Val-Cit-PAB-PNP

Product Name
FMoc-Val-Cit-PAB-PNP
CAS No.
863971-53-3
Chemical Name
FMoc-Val-Cit-PAB-PNP
Synonyms
4-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate;(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate;Moc-Val-Cit-PAB-PNP;Fmoc-Val-Cit-PAB-PN;FMoc-Val-Cit-PAB-PNP;Fmoc-Val-Cit-PABC-PNP;Fmoc-Val-Cit-PAB-PNP-OH;Fmoc-Val-Cit-PAB-PNP, >95%;863971-53-3 FMoc-Val-Cit-PAB-PNP 1g;FMOC-VAL-CIT-PAB-PNP (9-FLUORENYLMETHYLOXYCARBONYL-VALYL-CITRULLYL-(4-AMINOBENZYL)-(4-NITROPHENYL)CARBONATE)
CBNumber
CB92730904
Molecular Formula
C40H42N6O10
Formula Weight
766.8
MOL File
863971-53-3.mol
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FMoc-Val-Cit-PAB-PNP Property

Melting point:
189 °C(dec.)
Boiling point:
1024.0±65.0 °C(Predicted)
Density 
1.335±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
form 
powder to crystal
pka
10.63±0.46(Predicted)
color 
White to Light yellow
Sequence
Fmoc-Val-Cit-PAB-PNP
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Safety

HS Code 
2924.29.7790
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
F1114
Product name
Fmoc-Val-Cit-PAB-PNP
Packaging
100MG
Price
$161
Updated
2024/03/01
TCI Chemical
Product number
F1114
Product name
Fmoc-Val-Cit-PAB-PNP
Packaging
500MG
Price
$640
Updated
2024/03/01
BroadPharm
Product number
BP-22309
Product name
Fmoc-Val-Cit-PAB-PNP
Purity
95%
Packaging
500mg
Price
$750
Updated
2021/12/16
BroadPharm
Product number
BP-22309
Product name
Fmoc-Val-Cit-PAB-PNP
Purity
95%
Packaging
100mg
Price
$255
Updated
2021/12/16
Iris Biotech GmbH
Product number
ADC1000
Product name
Fmoc-Val-Cit-PAB-PNP
Packaging
250mg
Price
$337.5
Updated
2021/12/16
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FMoc-Val-Cit-PAB-PNP Chemical Properties,Usage,Production

Description

Fmoc-Val-Cit-PAB-PNP is a a cleavable ADC linker used in antibody drug conjugate. The Val-Cit linker was designed to be cleaved by cathepsin B. PNP group is a good leaving group when reacting with amine bearing payload.

Biological Activity

Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).

FMoc-Val-Cit-PAB-PNP Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from FMoc-Val-Cit-PAB-PNP manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Fmoc-Val-Cit-PAB-PNP 863971-53-3
Price
US $0.00/g
Min. Order
5g
Purity
>95.00%
Supply Ability
5g
Release date
2024-03-29
Career Henan Chemical Co
Product
FMoc-Val-Cit-PAB-PNP 863971-53-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-18
Career Henan Chemical Co
Product
FMoc-Val-Cit-PAB-PNP 863971-53-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-18

863971-53-3, FMoc-Val-Cit-PAB-PNPRelated Search:


  • {4-[(2S)-5-(carbamoylamino)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]pentanamido]phenyl}methyl 4-nitrophenyl carbonate
  • Moc-Val-Cit-PAB-PNP
  • 4-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate
  • Fmoc-Val-Cit-PAB-PNP, >95%
  • FMoc-Val-Cit-PAB-PNP
  • (9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate
  • L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
  • FMOC-VAL-CIT-PAB-PNP (9-FLUORENYLMETHYLOXYCARBONYL-VALYL-CITRULLYL-(4-AMINOBENZYL)-(4-NITROPHENYL)CARBONATE)
  • 863971-53-3 FMoc-Val-Cit-PAB-PNP 1g
  • Fmoc-Val-Cit-PABC-PNP
  • Fmoc-Val-Cit-PAB-PNP-OH
  • Fmoc-Val-Cit-PAB-PN
  • 863971-53-3
  • 63971-53-3
  • C40H42N6O10
  • Pharmaceutical
  • ADCs
  • ADC-Linker
  • ADC-Linkers