TMRE

Product Name: TMRE
CAS No.: 115532-52-0
Chemical Name: TMRE
Synonyms: TMRE;T 669;TMRE.ClO4;TMRE, PERCHLORATE;TMRE, 10 mM in DMSO;xanthylium perchlorate;3,6-Bis(dimethylamino);TMRE(Tetramethylrhodamine ethyl ester);TETRAMETHYLRHODAMINE ETHYL ESTER PERCHLORATE;TMRE Membrane Potential Fluorescent Probes (Red)
CBNumber: CB9279045
Molecular Formula: C26H27ClN2O7
Formula Weight: 514.96
MOL File: 115532-52-0.mol

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TMRE Property

Melting point:: 264–266℃
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO: soluble
form: crystals
color: Dark green
Appearance: dark colored solid
λmax: 549 nm
Biological Applications: Detecting mitochondrial membrane potential; apoptosis assays; multidrug resistance assays
Major Application: Semi-conducting polymer nanoparticles
InChIKey: NBAOBNBFGNQAEJ-UHFFFAOYSA-M
SMILES: Cl([O-])(=O)(=O)=O.C(C1C=CC=CC=1C1C2=CC=C(N(C)C)C=C2[O+]=C2C=C(N(C)C)C=CC=12)(=O)OCC

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Safety

Hazard Codes: Xn
Risk Statements: 20/22-36/38
Safety Statements: 26-36
WGK Germany: 3
F: 8-10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 87917
Product name: Tetramethylrhodamine ethyl ester perchlorate
Purity: suitable for fluorescence, ≥90% (HPCE)
Packaging: 25mg
Price: $210
Updated: 2025/07/31

Cayman Chemical

Product number: 21426
Product name: Tetramethylrhodamine ethyl ester (perchlorate)
Purity: ≥98%
Packaging: 5mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 21426
Product name: Tetramethylrhodamine ethyl ester (perchlorate)
Purity: ≥98%
Packaging: 10mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 21426
Product name: Tetramethylrhodamine ethyl ester (perchlorate)
Purity: ≥98%
Packaging: 25mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 21426
Product name: Tetramethylrhodamine ethyl ester (perchlorate)
Purity: ≥98%
Packaging: 50mg
Price: $195
Updated: 2024/03/01

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TMRE Chemical Properties,Usage,Production

Description

TMRE is widely used for labeling mitochondria in live cells but not compatible with fixation. This lipophilic and positively charged dye rapidly permeates plasma membrane without interacting with membrane proteins and forming aggregates. TMRE selectively accumulates in active mitochondria due to their transmembrane potential.

In addition to staining mitochondria for imaging purposes, TMRE is used for quantitative measurements of mitochondria membrane potential using Nernst equation. The dye serves as a tool to study mitochondrial function changes and cell viability in response to stimuli or pharmaceuticals of interest. Mitochondrial depolarization caused by apoptosis, necrosis or other factors is characterized by decreased membrane potential and is indicated with decreased fluorescence compared to intact cells that have polarized mitochondria.

TMRE applications include fluorescent microscopy, flow cytometry, microplate assays. The dye has an excitation maximum at 549 nm: it can be effectively excited by the blue (488 nm) or yellow-green (561 nm) lasers. Emission of the dye can be detected in PE channel (maximum at 574 nm).

Uses

Tetramethylrhodamine Ethyl Ester Perchlorate is a fluorescent probe which is used in measuring membrane potential changes in mitochondria.

Definition

ChEBI: Tetramethylrhodamine ethyl ester perchlorate is an organic perchlorate salt that has tetramethylrhodamine ethyl ester(1+) as the cation. It is used as a cell-permeant, cationic, red-orange fluorescent dye that is readily sequestered by active mitochondria. It has a role as a fluorochrome and a reagent. It is a xanthene dye and an organic perchlorate salt. It contains a tetramethylrhodamine ethyl ester(1+).

Abs/Em Maxima

552/575 nm

Excitation / Emission Maximum

550 nm/575 nm

TMRE Preparation Products And Raw materials

Raw materials

Preparation Products

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TMRE Suppliers

China 124 Germany 1 India 1 Switzerland 1 United States 15 Global 142

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
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Aladdin Scientific

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Alfa Chemistry

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Amfinecom Inc.

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3B Scientific Corporation

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Abcam Limited

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Cayman Chemical Company

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United States Biological

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MedChemExpress

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Riedel-de Haen AG

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Matrix Scientific

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AAT Bioquest, Inc.

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Zymed Laboratories Inc.

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AnaSpec, Inc.

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Biotium, Inc.

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View Lastest Price from TMRE manufacturers

Career Henan Chemical Co

Product: [6-(dimethylamino)-9-(2-ethoxycarbonylphenyl)xanthen-3-ylidene]-dimethylazanium,perchlorate 115532-52-0
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2019-12-31

115532-52-0, TMRERelated Search:

ETHYL METHYL ETHER 2-METHYL-1,3-PROPANEDIOL 3,3'-DIHEXYLOXACARBOCYANINE IODIDE DIHYDRORHODAMINE 123 JC-1 Rhodamine 123 NONYL ACRIDINE ORANGE TETRAMETHYLRHODAMINE METHYL ESTER PERCHLORATE TETRAMETHYLRHODAMINE, ETHYL ESTER, PERCHLORATE (TMRE) TMRE RHODAMINE B, HEXYL ESTER PERCHLORATE [3H(G)]

TMRE

TMRE, PERCHLORATE

TETRAMETHYLRHODAMINE ETHYL ESTER PERCHLORATE

XanthyliuM, 3,6-bis(diMethylaMino)-9-[2-(ethoxycarbonyl)phenyl]-, perchlorate (1:1)

3,6-bis(diMethylaMino)-9-(2-(ethoxycarbonyl)phenyl)xanthyliuM

TMRE [TetraMethylrhodaMine, ethyl ester, perchlorate]

3,6-Bis(diMethylaMino)-9-(2-(ethoxycarbonyl)phenyl)xanthyliuM perchlorate

3,6-Bis(dimethylamino)

xanthylium perchlorate

T 669

TMRE [Tetramethylrhodamine ethyl ester] *CAS#: 115532-52-0*

[6-(dimethylamino)-9-(2-ethoxycarbonylphenyl)xanthen-3-ylidene]-dimethylazanium,perchlorate

TMRE(Tetramethylrhodamine ethyl ester)

TMRE.ClO4

TMRE,Tetramethylrhodamine ethyl ester,Inhibitor,inhibit

TMRE, 10 mM in DMSO

TMRE [Tetramethylrhodamine, ethyl ester, perchlorate] - 25 mg

TMRE Membrane Potential Fluorescent Probes (Red)

115532-52-0

C26H27N2O3

C26H27ClN2O7

Fluorescent Probes, Labels, Particles and Stains

Detection

Biochemicals and Reagents

BioChemical

Xanthene