4-Amino-3-chlorobenzonitrile
- Product Name
- 4-Amino-3-chlorobenzonitrile
- CAS No.
- 21803-75-8
- Chemical Name
- 4-Amino-3-chlorobenzonitrile
- Synonyms
- BUTTPARK 29\06-54;2-CHLORO-4-CYANOANILINE;3-CHLORO-4-AMINBENZONITRILE;4-AMINO-3-CHLOROBENZONITRILE;3-CHLORO-4-AMINOBENZONITRILE;4-amino-3-chlorobenoznitrile;1-aMino-2-chloro-4-cyanobenzene;Benzonitrile, 4-amino-3-chloro-;4-Amino-3-chlorobenzonitrile >4-Amino-3-chlorobenzonitrile,97%
- CBNumber
- CB9298307
- Molecular Formula
- C7H5ClN2
- Formula Weight
- 152.58
- MOL File
- 21803-75-8.mol
4-Amino-3-chlorobenzonitrile Property
- Melting point:
- 102-105 °C(lit.)
- Boiling point:
- 277.8±25.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- -0.22±0.10(Predicted)
- color
- Light yellow to Brown to Dark green
- BRN
- 1817655
- InChI
- 1S/C7H5ClN2/c8-6-3-5(4-9)1-2-7(6)10/h1-3H,10H2
- InChIKey
- OREVCMGFYSUYPX-UHFFFAOYSA-N
- SMILES
- Nc1ccc(cc1Cl)C#N
- CAS DataBase Reference
- 21803-75-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36/37-36/37/39
- RIDADR
- 3276
- WGK Germany
- 3
- Hazard Note
- Harmful/Irritant
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29269090
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 519596
- Product name
- 4-Amino-3-chlorobenzonitrile
- Purity
- 97%
- Packaging
- 5g
- Price
- $178
- Updated
- 2025/07/31
- Product number
- 519596
- Product name
- 4-Amino-3-chlorobenzonitrile
- Purity
- 97%
- Packaging
- 25g
- Price
- $604
- Updated
- 2023/06/20
- Product number
- A1962
- Product name
- 4-Amino-3-chlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $67
- Updated
- 2025/07/31
- Product number
- A1962
- Product name
- 4-Amino-3-chlorobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $258
- Updated
- 2023/01/07
- Product number
- A578308
- Product name
- 4-Amino-3-chlorobenzonitrile
- Packaging
- 5g
- Price
- $60
- Updated
- 2021/12/16
4-Amino-3-chlorobenzonitrile Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Definition
ChEBI: 4-Amino-3-chlorobenzonitrile is a member of benzenes and a nitrile.
Synthesis
873-74-5
21803-75-8
Step 1: N-chlorosuccinimide (12.4 g, 93 mmol) was slowly added to a stirred solution of 4-aminobenzonitrile (10.0 g, 84.7 mmol) in acetonitrile (100 mL) at 90 °C. After the addition was completed, the reaction mixture was stirred continuously at 90 °C for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure. The concentrated residue was dissolved in 500 mL of dichloromethane and washed with 5% aqueous sodium hydroxide. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give 4-amino-3-chlorobenzonitrile as a brown solid (12.2 g, 95% yield).1H NMR (300 MHz, CDCl3) δ 7.54 (d, J = 1.7 Hz, 1H), 7.35 (dd, J = 1.8,8.4 Hz, 1H), 6.77 (d, J = 8.5 Hz, 1H ), 4.63 (br s, 2H).
References
[1] Synlett, 1999, # 12, p. 1984 - 1986
[2] Patent: EP2766359, 2016, B1. Location in patent: Paragraph 0383
[3] Journal of Organic Chemistry, 2017, vol. 82, # 14, p. 7529 - 7537
[4] Organic Letters, 2008, vol. 10, # 1, p. 113 - 116
[5] Synthesis, 1985, # 6/7, p. 669 - 670
4-Amino-3-chlorobenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
4-Amino-3-chlorobenzonitrile Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44802
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2850
- Advantage
- 65
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 11776
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
View Lastest Price from 4-Amino-3-chlorobenzonitrile manufacturers
- Product
- 4-Amino-3-chlorobenzonitrile 21803-75-8
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08