4-Amino-3-chlorobenzonitrile

Product Name: 4-Amino-3-chlorobenzonitrile
CAS No.: 21803-75-8
Chemical Name: 4-Amino-3-chlorobenzonitrile
Synonyms: BUTTPARK 29\06-54;2-CHLORO-4-CYANOANILINE;3-CHLORO-4-AMINBENZONITRILE;4-AMINO-3-CHLOROBENZONITRILE;3-CHLORO-4-AMINOBENZONITRILE;4-amino-3-chlorobenoznitrile;1-aMino-2-chloro-4-cyanobenzene;Benzonitrile, 4-amino-3-chloro-;4-Amino-3-chlorobenzonitrile >4-Amino-3-chlorobenzonitrile,97%
CBNumber: CB9298307
Molecular Formula: C7H5ClN2
Formula Weight: 152.58
MOL File: 21803-75-8.mol

More

Less

4-Amino-3-chlorobenzonitrile Property

Melting point:: 102-105 °C(lit.)
Boiling point:: 277.8±25.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
form: powder to crystal
pka: -0.22±0.10(Predicted)
color: Light yellow to Brown to Dark green
BRN: 1817655
CAS DataBase Reference: 21803-75-8(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-36/37-36/37/39
RIDADR: 3276
WGK Germany: 3
Hazard Note: Harmful/Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29269090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 519596
Product name: 4-Amino-3-chlorobenzonitrile
Purity: 97%
Packaging: 5g
Price: $178
Updated: 2025/07/31

Sigma-Aldrich

Product number: 519596
Product name: 4-Amino-3-chlorobenzonitrile
Purity: 97%
Packaging: 25g
Price: $604
Updated: 2023/06/20

TCI Chemical

Product number: A1962
Product name: 4-Amino-3-chlorobenzonitrile
Purity: >98.0%(GC)
Packaging: 5g
Price: $67
Updated: 2025/07/31

TCI Chemical

Product number: A1962
Product name: 4-Amino-3-chlorobenzonitrile
Purity: >98.0%(GC)
Packaging: 25g
Price: $258
Updated: 2023/01/07

TRC

Product number: A578308
Product name: 4-Amino-3-chlorobenzonitrile
Packaging: 5g
Price: $60
Updated: 2021/12/16

More

Less

4-Amino-3-chlorobenzonitrile Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Definition

ChEBI: 4-Amino-3-chlorobenzonitrile is a member of benzenes and a nitrile.

Synthesis

873-74-5

21803-75-8

Step 1: N-chlorosuccinimide (12.4 g, 93 mmol) was slowly added to a stirred solution of 4-aminobenzonitrile (10.0 g, 84.7 mmol) in acetonitrile (100 mL) at 90 °C. After the addition was completed, the reaction mixture was stirred continuously at 90 °C for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure. The concentrated residue was dissolved in 500 mL of dichloromethane and washed with 5% aqueous sodium hydroxide. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give 4-amino-3-chlorobenzonitrile as a brown solid (12.2 g, 95% yield).1H NMR (300 MHz, CDCl3) δ 7.54 (d, J = 1.7 Hz, 1H), 7.35 (dd, J = 1.8,8.4 Hz, 1H), 6.77 (d, J = 8.5 Hz, 1H ), 4.63 (br s, 2H).

References

[1] Synlett, 1999, # 12, p. 1984 - 1986
[2] Patent: EP2766359, 2016, B1. Location in patent: Paragraph 0383
[3] Journal of Organic Chemistry, 2017, vol. 82, # 14, p. 7529 - 7537
[4] Organic Letters, 2008, vol. 10, # 1, p. 113 - 116
[5] Synthesis, 1985, # 6/7, p. 669 - 670

4-Amino-3-chlorobenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-Amino-3-chlorobenzonitrile Suppliers

Americas 1 Belgium 1 China 161 Europe 3 Germany 4 India 6 Japan 1 Switzerland 2 United Kingdom 19 United States 33 Global 231

AbaChemScene

Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
Country: United States
ProdList: 3982
Advantage: 60

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Aceschem Inc.

Tel: +1-817863-6948 +1-（817）863-6948
Email: sales@aceschem.com
Country: United States
ProdList: 19632
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

SynQuest Laboratories, Inc.,

Tel: --
Fax: --
Country: United States
ProdList: 2301
Advantage: 58

Alichem Inc.

Tel: --
Fax: --
Email: sales@alichem.com
Country: United States
ProdList: 6167
Advantage: 58

Chemphtec Corporation

Tel: --
Fax: --
Email: fo@chemphtec.com
Country: United States
ProdList: 2181
Advantage: 58

Advanced Chemical Intermediates Ltd.

Tel: --
Fax: --
Email: enquiries@acints.com
Country: United States
ProdList: 4893
Advantage: 58

OChem Incorporation

Tel: --
Fax: --
Email: sales@ocheminc.com
Country: United States
ProdList: 6501
Advantage: 60

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Frontier Scientific, Inc.

Tel: --
Fax: --
Email: sales@frontiersci.com
Country: United States
ProdList: 6222
Advantage: 86

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

Oakwood Products, Inc.

Tel: --
Fax: --
Email: sales@oakwoodchemical.com
Country: United States
ProdList: 6193
Advantage: 74

Ryan Scientific, Inc.

Tel: --
Fax: --
Email: ryan.reichlyn@ryansci.com
Country: United States
ProdList: 6439
Advantage: 60

Ivy Fine Chemicals

Tel: --
Fax: --
Email: sales@ivychem.com
Country: United States
ProdList: 6493
Advantage: 58

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

ASDI Incorporated

Tel: --
Fax: --
Email: customerservice@asdi.net
Country: United States
ProdList: 6922
Advantage: 67

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

Pfaltz & Bauer, Inc.

Tel: --
Fax: --
Email: sales@pfaltzandbauer.com
Country: United States
ProdList: 6828
Advantage: 72

Aagile Labs Division of Tyger Scientific

Tel: --
Fax: --
Email: tygersci@yahoo.com
Country: United States
ProdList: 6568
Advantage: 68

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

More

Less

View Lastest Price from 4-Amino-3-chlorobenzonitrile manufacturers

Career Henan Chemical Co

Product: 4-Amino-3-chlorobenzonitrile 21803-75-8
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

21803-75-8, 4-Amino-3-chlorobenzonitrileRelated Search:

Glucosamine p-Tolunitrile 3-Aminophenol ALTRENOGEST 4-Aminobenzonitrile EC 2.6.1.2 Acetaminophen 2-Chlorobenzonitrile Sulfamic acid Benzonitrile 4-Nitrobenzonitrile 6-Aminocaproic acid 3-Aminopyridine 2-Cyanophenol 4-Chlorobenzonitrile Glycine Tris(hydroxymethyl)aminomethane Difluorochloromethane

BUTTPARK 29\06-54

3-CHLORO-4-AMINOBENZONITRILE

3-CHLORO-4-AMINBENZONITRILE

4-AMINO-3-CHLOROBENZONITRILE

2-CHLORO-4-CYANOANILINE

4-Amino-3-chlorobenzonitrile,97%

1-aMino-2-chloro-4-cyanobenzene

4-Amino-3-chlorobenzonitrile &gt

Benzonitrile, 4-amino-3-chloro-

4-amino-3-chlorobenoznitrile

21803-75-8

Building Blocks

C6 to C7

Nitrogen Compounds

Organic Building Blocks

Cyanides/Nitriles

Aromatic Nitriles

Nitrile

C6 to C7

Cyanides/Nitriles

Nitrogen Compounds