ChemicalBook > CAS DataBase List > UNC3866

UNC3866

Product Name
UNC3866
CAS No.
1872382-47-2
Chemical Name
UNC3866
Synonyms
CS-2491;UNC3866;UNC 3866;UNC-3866;UNC3866, 10 mM in DMSO;UNC3866,inhibit,Histone Methyltransferase,UNC-3866,Inhibitor,UNC 3866;N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine methyl ester;L-Serine, N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-, methyl ester;(3S,6S,9S,12S,15S)-Methyl 3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate
CBNumber
CB93153225
Molecular Formula
C43H66N6O8
Formula Weight
795.02
MOL File
1872382-47-2.mol
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UNC3866 Property

Boiling point:
1034.5±65.0 °C(Predicted)
Density 
1.129±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Soluble in DMSO
form 
A crystalline solid
pka
13.39±0.46(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19237
Product name
UNC3866
Purity
≥95%
Packaging
1mg
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
19237
Product name
UNC3866
Purity
≥95%
Packaging
5mg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
19237
Product name
UNC3866
Purity
≥95%
Packaging
10mg
Price
$278
Updated
2024/03/01
Cayman Chemical
Product number
19237
Product name
UNC3866
Purity
≥95%
Packaging
25mg
Price
$578
Updated
2024/03/01
TRC
Product number
D462375
Product name
N-​[4-​(1,​1-Dimethylethyl)​benzoyl]​-​L-​phenylalanyl-​L-​alanyl-​L-​leucyl-​N6,​N6-​diethyl-​L-​lysyl-​L-serineMethylEster
Packaging
5mg
Price
$420
Updated
2021/12/16
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UNC3866 Chemical Properties,Usage,Production

Description

UNC3866 is an inhibitor of chromobox homolog 7 (CBX7; Kd = 97 nM). It also binds to CBX4 (Kd = 94 nM) but is greater than 6-fold selective over CBX2, 6, and 8 and the chromodomain Y family (CDY) chromodomains CDY1, L1b, and L2 (Kds = 0.61-6.3 μM). UNC3866 pretreatment (30 μM) of PC3 lysates completely inhibits chemiprecipitation of CBX7. It induces a senescent-like morphology and reduces growth of PC3 cells with an EC50 value of 7.6 μM.

Uses

Polycomb group proteins (CBX4, CBX7) regulate cell fate decisions during embryogenesis. N-?[4-?(1,?1-Dimethylethyl)?benzoyl]?-?L-?phenylalanyl-?L-?alanyl-?L-?leucyl-?N6,?N6-?diethyl-?L-?lysyl-?L-serine Methyl Ester is a selective antagonist of CBX4 and CBX7 chromodomains. It also inhibits prostate cell proliferation.

UNC3866 Preparation Products And Raw materials

Raw materials

Preparation Products

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UNC3866 Suppliers

China 62 India 1 United Kingdom 1 United States 10 Global 74
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
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View Lastest Price from UNC3866 manufacturers

Career Henan Chemical Co
Product
UNC3866 1872382-47-2
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-13

1872382-47-2, UNC3866Related Search:

UNC0321 UNC3230 UNC2881 UNC2541 UNC 1079 UNC 0224 UNC0379 UNC 669 UNC2250 UNC-1215 UNC-926 Hydochloride UNC569 UNC0646 NUC-7738 UNC2025 UNC0638 UNC-0642 UNC 0631

  • UNC3866
  • N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine methyl ester
  • CS-2491
  • UNC 3866;UNC-3866
  • (3S,6S,9S,12S,15S)-Methyl 3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate
  • L-Serine, N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-, methyl ester
  • UNC3866,inhibit,Histone Methyltransferase,UNC-3866,Inhibitor,UNC 3866
  • UNC3866, 10 mM in DMSO
  • 1872382-47-2
  • C43H66N6O8