ChemicalBook > CAS DataBase List > SB-756050

SB-756050

Product Name
SB-756050
CAS No.
447410-57-3
Chemical Name
SB-756050
Synonyms
SB-756050;SB-756050, >98%;SB756050;SB 756050;SB-756050;1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane;1H-1,4-Diazepine, 1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]hexahydro-;G protein-coupled Bile Acid Receptor 1,inhibit,TGR5,Inhibitor,SB756050,GPBAR1,G-protein coupled receptor 19,GPCR19
CBNumber
CB93162605
Molecular Formula
C21H28N2O8S2
Formula Weight
500.59
MOL File
447410-57-3.mol
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SB-756050 Property

Boiling point:
653.1±65.0 °C(Predicted)
Density 
1.328±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.25 mg/ml; DMSO: 10 mg/ml
form 
A crystalline solid
pka
-6.97±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27998
Product name
SB-756050
Packaging
50mg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
27998
Product name
SB-756050
Packaging
100mg
Price
$208
Updated
2024/03/01
Cayman Chemical
Product number
27998
Product name
SB-756050
Packaging
10mg
Price
$33
Updated
2024/03/01
ChemScene
Product number
CS-6960
Product name
SB756050
Purity
99.32%
Packaging
10mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-6960
Product name
SB756050
Purity
99.32%
Packaging
25mg
Price
$135
Updated
2021/12/16
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SB-756050 Chemical Properties,Usage,Production

Description

SB-756050 is an agonist of the bile acid G protein-coupled receptor TGR5 (EC50 = 1.3 μM for the human receptor). It is selective for TGR5 over the farnesoid X receptor (FXR) and a panel of other receptors, channels, and transporters. SB-756050 (10-100 mg/kg) decreases fasting glucose levels and increases glucose disposal rate and insulin secretion in diabetic Goto Kakizaki rats.

SB-756050 Preparation Products And Raw materials

Raw materials

Preparation Products

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SB-756050 Suppliers

China 44 United States 5 Global 49
Dalian Meilun Biotech Co., Ltd.
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447410-57-3, SB-756050Related Search:

MMP-2/MMP-9 INHIBITOR IV SB 200646 HYDROCHLORIDE SB 200646 HYDROCHLORIDE m-tolyl 5-chloro-2-(ethylsulfonyl)pyrimidine-4-carboxylate SB 202190 SB 431542 SB 743921 5-[2-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-1H-inden-1-one oxime Pracinostat 6-[2-tert-Butyl-5-(6-methyl-pyridin-2-yl)-1H-imidazol-4-yl]-quinoxaline 4'-CHLORO-3-METHOXYCINNAMANILIDE SB-705498 SB 203580 SB 225002 SB242235 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride

  • SB-756050
  • 1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane
  • SB756050;SB 756050;SB-756050
  • SB-756050, >98%
  • 1H-1,4-Diazepine, 1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]hexahydro-
  • G protein-coupled Bile Acid Receptor 1,inhibit,TGR5,Inhibitor,SB756050,GPBAR1,G-protein coupled receptor 19,GPCR19
  • 447410-57-3