ChemicalBook > CAS DataBase List > 2'-O-Methylcytidine

2'-O-Methylcytidine

Product Name
2'-O-Methylcytidine
CAS No.
2140-72-9
Chemical Name
2'-O-Methylcytidine
Synonyms
4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one;OMe-rC;2'-OMe-C;2'-OMe-C;2'-OMe-rC;2'-OMe-Cr;2'-O-Me-dC;2'-O-Me-rC;2'-OMe Cytidine;2'-OMe-cytidine
CBNumber
CB9324099
Molecular Formula
C10H15N3O5
Formula Weight
257.24
MOL File
2140-72-9.mol
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2'-O-Methylcytidine Property

Melting point:
252-253 C
Boiling point:
506.0±60.0 °C(Predicted)
Density 
1.68±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
Soluble in DMSO.
pka
13.37±0.70(Predicted)
form 
Powder
color 
White to Off-white
PH
4.2
λmax
281 (pH 1)；273 (EtOH)
InChI
InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
InChIKey
RFCQJGFZUQFYRF-ZOQUXTDFSA-N
SMILES
OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OC)[C@@H]1O
CAS DataBase Reference
2140-72-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2317
Product name
2'-O-Methylcytidine
Purity
>98.0%(HPLC)(T)
Packaging
200mg
Price
$47
Updated
2024/03/01
TCI Chemical
Product number
M2317
Product name
2'-O-Methylcytidine
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$185
Updated
2024/03/01
Alfa Aesar
Product number
J65528
Product name
2'-O-Methylcytidine, 99%
Packaging
1g
Price
$64.65
Updated
2024/03/01
Usbiological
Product number
296261
Product name
2'-O-Methylcytidine
Packaging
300mg
Price
$333
Updated
2021/12/16
TRC
Product number
M294660
Product name
2’-O-MethylCytidine
Packaging
5g
Price
$480
Updated
2021/12/16
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2'-O-Methylcytidine Chemical Properties,Usage,Production

Description

2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon, making it an effective viral replication inhibitor. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways and may be able to bind to the response element on DNA, which could inhibit protein synthesis in cancer cells. It is an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.8 μM). It inhibits HCV replication in a replicon assay (IC50 = 21.2 μM).

Chemical Properties

White powder

Uses

2'-O-Methylcytidine is used in the preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.

Uses

Cytidine analog.

Definition

ChEBI: 2'-O-methylcytidine is a methylcytidine.

2'-O-Methylcytidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-O-Methylcytidine Suppliers

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View Lastest Price from 2'-O-Methylcytidine manufacturers

Yunbio Tech Co.,Ltd.
Product
2'-O-Methylcytidine 2140-72-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
300KG per month
Release date
2023-03-04
Henan Fengda Chemical Co., Ltd
Product
2'-O-Methylcytidine 2140-72-9
Price
US $6.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
Zhejiang Hengkang Pharmaceutical Co., Ltd.
Product
2'-O-Methylcytidine 2140-72-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
500kg per month
Release date
2022-12-27

2140-72-9, 2'-O-MethylcytidineRelated Search:

(Trifluoromethoxy)benzene Anisole Methoxyacetic acid 4-Methoxybenzoic acid p-Anisidine p-Anisaldehyde Methoxydiethylborane POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE 2'-O-Methyl-N4-Benzoyl-5'-O-DMT-Cytidine (R)-(-)-TETRAHYDROFURFURYL ALCOHOL (S)-(+)-1-DIMETHYLAMINO-2-PROPANOL 3-Methylcytidine 2''-METHYLCYTIDINE,2'-C-METHYLCYTIDINE 2''-DEOXY-5-METHYLCYTIDINE (5-METHYL-2''-DEOXYCYTIDINE),2'-DEOXY-5-METHYLCYTIDINE N4-BENZOYL-2'-O-METHYLCYTIDINE 2'-O-Methyl-N4-Acetyl-5'-O-DMT-Cytidine 5-Methylcytidine N4-Acetyl-2'-O-Methyl-cytidine

  • 2'-OMe-C
  • 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one
  • 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one
  • 4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one
  • 2'-OMe Cytidine
  • 4-aMino-1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2-dihydropyriMidin-2-one
  • 2'-O-Methylcytidine, >98.0%(HPLC)
  • 2'-O-Methylcytidine, >=99%
  • 2'-O-METHYLCYTIDINE
  • 2''-(O-METHYL)-CYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
  • 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one
  • 2'-O-Methylcytidineanhydrous
  • 2'-O-Methyl-D-cytidine
  • 2'-O-Methylcytidine&gt
  • 2'-OMe-rC
  • 2'-O-Methylcytidine USP/EP/BP
  • 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2-dihydropyrimidin-2-one
  • 2'-OMe-Cr
  • 2’-O-Methyl cytidine, RNA nucleoside Cm
  • OMe-rC
  • 2'-O-Methylcytidine
  • 2'-OMe-cytidine
  • 2'-O-Me-dC
  • 2'-O-Me-rC
  • Cytidine, 2'-O-methyl-
  • 2'-OMe-C
  • 2140-72-9
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleoside Analogs
  • BioChemical
  • Biochemicals and Reagents
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Heterocycles
  • Nucleotides
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides
  • Modified（deoxy）nucleoside
  • Nucleosides-2'-OMe Nucleosides