ChemicalBook > CAS DataBase List > 2'-O-Methylcytidine

2'-O-Methylcytidine

Product Name
2'-O-Methylcytidine
CAS No.
2140-72-9
Chemical Name
2'-O-Methylcytidine
Synonyms
4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one;OMe-rC;2'-OMe-C;2'-OMe-C;2'-OMe-rC;2'-OMe-Cr;2'-O-Me-dC;2'-O-Me-rC;2'-OMe Cytidine;2'-OMe-cytidine
CBNumber
CB9324099
Molecular Formula
C10H15N3O5
Formula Weight
257.24
MOL File
2140-72-9.mol
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2'-O-Methylcytidine Property

Melting point:
252-253 C
Boiling point:
506.0±60.0 °C(Predicted)
Density 
1.68±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
Soluble in DMSO.
pka
13.37±0.70(Predicted)
form 
Powder
color 
White to Off-white
PH
4.2
λmax
281 (pH 1);273 (EtOH)
InChI
InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
InChIKey
RFCQJGFZUQFYRF-ZOQUXTDFSA-N
SMILES
OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OC)[C@@H]1O
CAS DataBase Reference
2140-72-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2317
Product name
2'-O-Methylcytidine
Purity
>98.0%(HPLC)(T)
Packaging
200mg
Price
$47
Updated
2024/03/01
TCI Chemical
Product number
M2317
Product name
2'-O-Methylcytidine
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$185
Updated
2024/03/01
Alfa Aesar
Product number
J65528
Product name
2'-O-Methylcytidine, 99%
Packaging
1g
Price
$64.65
Updated
2024/03/01
Usbiological
Product number
296261
Product name
2'-O-Methylcytidine
Packaging
300mg
Price
$333
Updated
2021/12/16
TRC
Product number
M294660
Product name
2’-O-MethylCytidine
Packaging
5g
Price
$480
Updated
2021/12/16
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2'-O-Methylcytidine Chemical Properties,Usage,Production

Description

2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon, making it an effective viral replication inhibitor. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways and may be able to bind to the response element on DNA, which could inhibit protein synthesis in cancer cells. It is an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.8 μM). It inhibits HCV replication in a replicon assay (IC50 = 21.2 μM).

Chemical Properties

White powder

Uses

2'-O-Methylcytidine is used in the preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.

Uses

Cytidine analog.

Definition

ChEBI: 2'-O-methylcytidine is a methylcytidine.

2'-O-Methylcytidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-O-Methylcytidine Suppliers

Zhejiang Huida Biotech Co., LTD
Tel
0571-0571-89903882 15990081639
Email
sunshixuan@huidabiotech.com
Country
China
ProdList
3705
Advantage
58
Jiangsu Synthgene Biotechnology Co.,Ltd.
Tel
18136497538
Email
znf@syngenebio.com
Country
China
ProdList
901
Advantage
58
Wuhu Huaren Science and Technology Co., Ltd.
Tel
0553-0553-0553-5842013-801-801 18155347026
Fax
086-553-5843138
Email
jinhuaren@huarensh.com
Country
China
ProdList
295
Advantage
64
Hefei Huana Biomedical Technology Co.,Ltd
Tel
17333066501
Email
shengwen.fang@huanaok.com.cn
Country
China
ProdList
95
Advantage
58
Allbiosyn Biotechnology Co.,LTD
Tel
18666985712
Email
info@allbiosyn.com
Country
China
ProdList
285
Advantage
58
Shanghai shuodian Biotechnology Co., Ltd
Tel
18221553137
Email
ddwuyu@126.com
Country
China
ProdList
823
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
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View Lastest Price from 2'-O-Methylcytidine manufacturers

Yunbio Tech Co.,Ltd.
Product
2'-O-Methylcytidine 2140-72-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
300KG per month
Release date
2023-03-04
Henan Fengda Chemical Co., Ltd
Product
2'-O-Methylcytidine 2140-72-9
Price
US $6.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
Zhejiang Hengkang Pharmaceutical Co., Ltd.
Product
2'-O-Methylcytidine 2140-72-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
500kg per month
Release date
2022-12-27

2140-72-9, 2'-O-MethylcytidineRelated Search:


  • 2'-OMe-C
  • 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one
  • 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one
  • 4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one
  • 2'-OMe Cytidine
  • 4-aMino-1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2-dihydropyriMidin-2-one
  • 2'-O-Methylcytidine, >98.0%(HPLC)
  • 2'-O-Methylcytidine, >=99%
  • 2'-O-METHYLCYTIDINE
  • 2''-(O-METHYL)-CYTIDINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
  • 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one
  • 2'-O-Methylcytidineanhydrous
  • 2'-O-Methyl-D-cytidine
  • 2'-O-Methylcytidine&gt
  • 2'-OMe-rC
  • 2'-O-Methylcytidine USP/EP/BP
  • 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2-dihydropyrimidin-2-one
  • 2'-OMe-Cr
  • 2’-O-Methyl cytidine, RNA nucleoside Cm
  • OMe-rC
  • 2'-O-Methylcytidine
  • 2'-OMe-cytidine
  • 2'-O-Me-dC
  • 2'-O-Me-rC
  • Cytidine, 2'-O-methyl-
  • 2'-OMe-C
  • 2140-72-9
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleoside Analogs
  • BioChemical
  • Biochemicals and Reagents
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Heterocycles
  • Nucleotides
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides
  • Modified(deoxy)nucleoside
  • Nucleosides-2'-OMe Nucleosides