2,6-Difluorobenzoyl chloride
- Product Name
- 2,6-Difluorobenzoyl chloride
- CAS No.
- 18063-02-0
- Chemical Name
- 2,6-Difluorobenzoyl chloride
- Synonyms
- FAC;SKL1224;FUROIC ACID;96.0%(T&2,6-difluoro;2-CARBOXYFURAN;PYROMUCIC ACID;ALPHA-FUROIC ACID;AKOS BBS-00003916;AKOS BBS-00003721
- CBNumber
- CB9331536
- Molecular Formula
- C7H3ClF2O
- Formula Weight
- 176.55
- MOL File
- 18063-02-0.mol
2,6-Difluorobenzoyl chloride Property
- Melting point:
- 128-132 °C(lit.)
- Boiling point:
- 72-77 °C/13 mmHg (lit.)
- Density
- 1.404 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.501(lit.)
- Flash point:
- 121 °F
- storage temp.
- Inert atmosphere,Room Temperature
- form
- clear liquid
- color
- Colorless to Light orange to Yellow
- Specific Gravity
- 1.404
- Water Solubility
- REACTS
- Sensitive
- Moisture Sensitive
- BRN
- 639438
- InChI
- InChI=1S/C7H3ClF2O/c8-7(11)6-4(9)2-1-3-5(6)10/h1-3H
- InChIKey
- QRHUZEVERIHEPT-UHFFFAOYSA-N
- SMILES
- C(Cl)(=O)C1=C(F)C=CC=C1F
- CAS DataBase Reference
- 18063-02-0(CAS DataBase Reference)
- NIST Chemistry Reference
- 2,6-Difluorobenzoyl chloride(18063-02-0)
Safety
- Hazard Codes
- C
- Risk Statements
- 36/37/38-34-10
- Safety Statements
- 26-36/37/39-45-28A-16
- RIDADR
- UN 2920 8/PG 2
- WGK Germany
- 3
- RTECS
- LV1763000
- F
- 21
- Hazard Note
- Corrosive
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29163990
- Storage Class
- 3 - Flammable liquids
- Hazard Classifications
- Eye Dam. 1
Flam. Liq. 3
Skin Corr. 1B
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 249408
- Product name
- 2,6-Difluorobenzoyl chloride
- Purity
- 99%
- Packaging
- 25g
- Price
- $61.1
- Updated
- 2023/01/07
- Product number
- 249408
- Product name
- 2,6-Difluorobenzoyl chloride
- Purity
- 99%
- Packaging
- 100g
- Price
- $238
- Updated
- 2023/01/07
- Product number
- D2798
- Product name
- 2,6-Difluorobenzoyl Chloride
- Purity
- >97.0%(GC)(T)
- Packaging
- 25g
- Price
- $149
- Updated
- 2026/03/19
- Product number
- D445485
- Product name
- 2,6-Difluorobenzoyl chloride
- Packaging
- 250g
- Price
- $580
- Updated
- 2021/12/16
- Product number
- FD71782
- Product name
- 2,6-Difluorobenzoyl chloride
- Packaging
- 250g
- Price
- $250
- Updated
- 2021/12/16
2,6-Difluorobenzoyl chloride Chemical Properties,Usage,Production
Chemical Properties
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID
Uses
Preservative, bactericide, furoates for perfume and flavoring, fumigant, textile processing, chemical intermediate.
Uses
2,6-Difluorobenzoyl chloride has been used in:
- the preparation of series of novel 2-aryl substituted 4H-3,1-benzoxazin-4-ones
- regioselective synthesis of 3,6-disubstituted-2-aminoimidazo[1,2-a]pyridine
- Friedel-Crafts acylation reaction of toluene, anisol, thioanisol, 4-phenoxyacetophenone and N,N-diacetyl-4-phenoxyaniline
Synthesis
Step 1: In a 250 ml three-necked flask equipped with a reflux condensing device, 2,6-difluorobenzoic acid, anhydrous KF, DMF and a small amount of catalyst were added sequentially, heated to reflux, the reaction was carried out for 8 h. The reaction was cooled, filtered, and the residue of the filtrate was washed with DMF, and the filtrate and the washings were combined, and the DMF was evaporated under reduced pressure, and washed, and filtered to obtain the intermediate product of 2,6-difluorobenzoic acid, a light yellow solid.
Step 2: In a 250 ml dry three-necked flask equipped with a reflux condensing device, add 2,6-difluorobenzoic acid, thionyl chloride and a small amount of catalyst in turn, heating to reflux, the reaction is 4h, evaporate the excess thionyl chloride, to get the product 2,6-difluorobenzoyl chloride, brownish yellow liquid.
2,6-Difluorobenzoyl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-Difluorobenzoyl chloride Suppliers
- Tel
- 021-31038972,31038973 17321035817
- Fax
- +86-21-51385350
- sales@harvest-chem.com
- Country
- China
- ProdList
- 2819
- Advantage
- 64
- Tel
- 021-50718719 13918719472
- Fax
- 021-50718719
- Country
- China
- ProdList
- 979
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44802
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2823
- Advantage
- 65
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
View Lastest Price from 2,6-Difluorobenzoyl chloride manufacturers
- Product
- 2,6-Difluorobenzoyl chloride 18063-02-0
- Price
- US $1.50/g
- Min. Order
- 1g
- Purity
- 99.0% Min
- Supply Ability
- 100 Tons
- Release date
- 2025-04-29
- Product
- 2,6-Difluorobenzoyl chloride 18063-02-0
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-08