Protopine

Product Name: Protopine
CAS No.: 130-86-9
Chemical Name: Protopine
Synonyms: BIFLORIN;Protopin;PROTOPINE;Biflorine;Corydinine;Tangeratin;Hypercorine;AKOS 243-72;Corydalis C;Protopine-RM
CBNumber: CB9347526
Molecular Formula: C20H19NO5
Formula Weight: 353.37
MOL File: 130-86-9.mol

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Protopine Property

Melting point:: 203-205?C
Boiling point:: 486.8°C (rough estimate)
Density: 1.399 (calc)
refractive index: 1.5800 (estimate)
storage temp.: Inert atmosphere,2-8°C
Water Solubility: Insoluble in water
solubility: DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic)
pka: 7.86±0.20(Predicted)
form: powder to crystal
color: White to Light gray to Light yellow
LogP: 3.760 (est)
NIST Chemistry Reference: Protopine(130-86-9)

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Safety

Safety Statements: 24/25
RIDADR: 1544
RTECS: VS2800000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29391900
Hazardous Substances Data: 130-86-9(Hazardous Substances Data)
Toxicity: guinea pig,LD50,intraperitoneal,116mg/kg (116mg/kg),Therapie. Vol. 28, Pg. 767, 1973.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89546
Product name: Protopine
Purity: phyproof? Reference Substance
Packaging: 10mg
Price: $425
Updated: 2024/03/01

TCI Chemical

Product number: P2611
Product name: Protopine
Purity: >98.0%(GC)
Packaging: 5mg
Price: $45
Updated: 2024/03/01

TCI Chemical

Product number: P2611
Product name: Protopine
Purity: >98.0%(GC)
Packaging: 25mg
Price: $130
Updated: 2024/03/01

TCI Chemical

Product number: P2611
Product name: Protopine
Purity: >98.0%(GC)
Packaging: 100mg
Price: $355
Updated: 2024/03/01

Usbiological

Product number: 300834
Product name: Protopine
Packaging: 20mg
Price: $320
Updated: 2021/12/16

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Protopine Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Protopine is a Ca2+ channel blocker and antiplatelet agent. Immunomodulator

Definition

ChEBI: A dibenzazecine alkaloid isolated from Fumaria vaillantii.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Purification Methods

It crystallises from EtOH/CHCl3. The picrate has m ~240o(dec). [Beilstein 27 H 558, 17 I 568, 17 II 620, 17 III/IV 6881.]

Protopine Preparation Products And Raw materials

Raw materials

Preparation Products

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Protopine Suppliers

Canada 1 China 173 Czech 1 France 2 Germany 1 India 3 Japan 1 United Kingdom 4 United States 19 Global 205

Stanford Chemicals Company

Tel: +1 (949) 468-0555
Fax: +1 (949) 812-6690
Email: sales@stanfordchem.com
Country: United States
ProdList: 13
Advantage: 60

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32159
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

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Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

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Country: United States
ProdList: 38630
Advantage: 58

ApexBio Technology

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Country: United States
ProdList: 6251
Advantage: 58

Wilshire Chemical Company Inc.

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Country: United States
ProdList: 3498
Advantage: 58

United States Biological

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Country: United States
ProdList: 6214
Advantage: 80

MedChemExpress

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Country: United States
ProdList: 6398
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Riedel-de Haen AG

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ProdList: 6773
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TCI America

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ProdList: 6909
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Frontier Scientific, Inc.

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ProdList: 6222
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HONEST JOY HOLDINGS LIMITED

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Country: United States
ProdList: 6675
Advantage: 54

FortopChem Technology Limited

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Country: United States
ProdList: 1099
Advantage: 50

MP Biomedicals, Inc.

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ProdList: 6561
Advantage: 81

Sinova Inc.

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Email: sales@sinovainc.com
Country: United States
ProdList: 4009
Advantage: 58

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View Lastest Price from Protopine manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Protopine 130-86-9
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-25

Career Henan Chemical Co

Product: Protopine 130-86-9
Price: US $9.80/KG
Min. Order: 1g
Purity: ＞98%
Supply Ability: 20 tons
Release date: 2020-02-10

130-86-9, ProtopineRelated Search:

Kresoxim-methyl Tribenuron methyl METSULFURON METHYL Methyl acetate Pirimiphos-methyl Methyl salicylate Protoporphyrin IX Thiophanate-methyl Methyl PROTOPINE HCL,PROTOPINE HYDROCHLORIDE NSC26657 DESOXYANISOIN 3-METHOXYPHENYLACETONE 3'-methoxypropiophenone CORYCAVINE PIPERONYL METHYL KETONE Methyl bromide [2-(4-METHOXY-PHENYL)-ETHYL]-METHYL-AMINE

7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-

7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one

Biflorine

Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-

Corydinine

Hypercorine

Protopin

BIFLORIN

AKOS 243-72

5,7-DIHYDROXY-2-METHYLCHROMONE-6-C-BETA-D-GLUCOPYRANOSIDE

PROTOPINE

4,6,7,14-Tetrahydro-5-methyl-bis[1,3]benzodioxolo[4,5-c-5',6'-g] azecin-13(5H)-one

7-Methyl-2,3:9,10-bis(methylenedioxy)-7,13a-secoberbin-13a-one

5-Methyl-9,10-(methylenedioxy)-4,6,7,13-tetrahydrobenzo[e]-1,3-dioxolo[4,5-l][2]benzazecine-12(5H)-one

6-Methyl-3,4-(methylenebisoxy)-10,11-(methylenebisoxy)-5,6,7,8-tetrahydrodibenzo[c,g]azecine-13(14H)-one

7-Methyl-6,7,8,9-tetrahydro-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,3]dioxolo[5',4':4,5]benzo[1,2-g]azecin-15(16H)-one

4,6,7,14-Tetrahydro-5-Methyl-

Tangeratin

Corydalis C

Protopine (Corydinine)

Protopine, 98%, from Corydalis yanhusuo W. T. Wang ex Z. Y. Su et C. Y. Wu

Protopine USP/EP/BP

1H-Isoindole-1,3(2H)-dione,2-(3-butyn-2-yl)-

Protopine 100 μg/ml Acetonitrile

Protopine-RM

Protopine, 10 mM in DMSO

130-86-9

C20H19O5

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals