Diclofenac potassium

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Diclofenac potassium

Description References

Product Name: Diclofenac potassium
CAS No.: 15307-81-0
Chemical Name: Diclofenac potassium
Synonyms: PotassiuM diclofenac;Cataflam;Keflan;ProSorb;K-fenak;Voltfast;CGP-45840B;Unii-L4D5ua6cb4;Diclofenac potassiu;Diclofenic potassiuM
CBNumber: CB9348932
Molecular Formula: C14H10Cl2KNO2
Formula Weight: 334.24
MOL File: 15307-81-0.mol

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Diclofenac potassium Property

Melting point:: 300-330 °C
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Sparingly soluble in water, freely soluble in methanol, soluble in ethanol (96 per cent), slightly soluble in acetone.
CAS DataBase Reference: 15307-81-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-51/53
Safety Statements: 61
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
HS Code: 2922492050

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H411Toxic to aquatic life with long lasting effects

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2441
Product name: Diclofenac potassium
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 500MG
Price: $280
Updated: 2024/03/01

Sigma-Aldrich

Product number: D1039990
Product name: Diclofenac potassium
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: d1039990
Price: $91.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1188709
Product name: Diclofenac potassium
Packaging: 200mg
Price: $786
Updated: 2024/03/01

Usbiological

Product number: 273151
Product name: Diclofenac potassium
Packaging: 1g
Price: $375
Updated: 2021/12/16

TRC

Product number: D436460
Product name: DiclofenacPotassiumSalt
Packaging: 250mg
Price: $230
Updated: 2021/12/16

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Diclofenac potassium Chemical Properties,Usage,Production

Description

Dichlofenac potassium is the potassium salt of dichlofenac. It is a nonsteroidal anti-inflammatory agent that can be used to reduce inflammation and as an analgesic to reduce pain in certain conditions. It can also used to treat dysmenorrhea. It can treat inflammatory disorders such as musculoskeletal complaints, dental pain, arthritis, actinic keratosis, joint pain, acute pain and chronic pain caused by certain kinds of cancers. Traditional opinion proposes that diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency. However, recent studies have shown that the pharmacologic activity of diclofenac goes beyond COX inhibition, and includes multimodal and, in some instances, novel mechanisms of action (MOA). For example, research suggests diclofenac can inhibit the thromboxane-prostanoid receptor, affect arachidonic acid release and uptake, inhibit lipoxygenase enzymes, and activate the nitric oxide–cGMP antinociceptive pathway. Other novel MOAs may include the inhibition of substrate P, inhibition of peroxisome proliferator activated receptor gamma (PPARγ), blockage of acid-sensing ion channels, alteration of interleukin-6 production, and inhibition of N-methyl-D-aspartate (NMDA) receptor hyperalgesia.

References

Brogden, R. N., et al. "Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin." Drugs 20.1 (1980): 24-48.
Gan, Tong J. "Diclofenac: an update on its mechanism of action and safety profile." Current medical research and opinion 26.7 (2010): 1715-1731.
Riihiluoma, P., E. Wuolijoki, and M. O. Pulkkinen. "Treatment of primary dysmenorrhea with diclofenac sodium." European Journal of Obstetrics & Gynecology and Reproductive Biology 12.3 (1981): 189-194.

Chemical Properties

White or slightly yellowish, slightly hygroscopic, crystalline powder.

Uses

Cyclo-oxygenase inhibitor; analgesic; anti-inflammatory.

Application

Diclofenac Potassium Salt is a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor.

Definition

ChEBI: The potassium salt of diclofenac.

brand name

Cataflam (Novartis).

Diclofenac potassium Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Diclofenac potassium manufacturers

Hong Kong Excellence Biotechnology Co., Ltd.

Product: Diclofenac potassium 15307-81-0
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 20tons
Release date: 2023-10-12

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Diclofenac Potassium 15307-81-0
Price: US $120.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-24

Shanghai Aosiris new Material Technology Co., LTD

Product: Diclofenac potassium 15307-81-0
Price: US $3.00-1.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 10 tons
Release date: 2024-04-01

15307-81-0, Diclofenac potassiumRelated Search:

Potassium chloride Potassium Acetate Potassium phenylacetate Potassium sorbate Potassium iodide Potassium Citrate Potassium persulfate 3,4'-DIAMINODIPHENYLMETHANE 2-Hydroxyphenylacetic acid 1-(2,6-Dichlorophenyl)-2-indolinone 6-Aminocaproic acid Diclofenac sodium Glycine 2-AMINOPHENYLACETIC ACID Phenylphosphonic dichloride Dichloromethylphenylsilane 2-ANILINOPHENYLACETIC ACID 2,6-DICHLORODIPHENYLAMINE

PotassiuM diclofenac

ProSorb

potassium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate

Diclofenic potassiuM

Benzeneaceticacid, 2-[(2,6-dichlorophenyl)aMino]-, potassiuM salt (1:1)

POTASSIUM [2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL]ACETATE

DICLOFENAC POTASSIUM

DICLOFENAC POTASSIUM SALT

2[(2,6-dichlorophenyl)amino]benzeneacetic acid potassium salt

Diclofenac potassium Joyce

sodium (6R,7R)-7-[[(2Z)-2-(2-imino-5H-thiazol-4-yl)-2-methoxyimino-1-oxoethyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Cataflam

CGP-45840B

K-fenak

Keflan

Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)-, monopotassium salt

Unii-L4D5ua6cb4

Voltfast

Diclofenac Potassium (200 mg)

DICLOFENAC POTASSIUM /POTASSIUM [2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL]ACETATE

Diclofenac potassium CRS

Diclofenac potassium USP/EP/BP

Diclofenac potassiu

Diclofenac potassiumQ: What is Diclofenac potassium Q: What is the CAS Number of Diclofenac potassium Q: What is the storage condition of Diclofenac potassium

Diclofenac Potassium (1188709)

15307-81-0

C14H11Cl2NO2K

C14H10CL2NKO2

C14H10Cl2KNO2

33424

chiral

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15307-81-0