ChemicalBook > CAS DataBase List > Taurodeoxycholic acid sodium salt

Taurodeoxycholic acid sodium salt

Product Name: Taurodeoxycholic acid sodium salt
CAS No.: 1180-95-6
Chemical Name: Taurodeoxycholic acid sodium salt
Synonyms: SODIUM TAURODEOXYCHOLATE;Taurodeoxycholate sodium salt;Taurodeoxycholic acid sodium salt hydrate;5B2;12B1;sodium 2-[[(3B1;sodium taurodeoxylate;SodiuM taurodeoxycholat;Sodium deoxytaurocholate;Taurodeoxycholate sodium
CBNumber: CB9349065
Molecular Formula: C26H44NNaO6S
Formula Weight: 521.69
MOL File: 1180-95-6.mol

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Taurodeoxycholic acid sodium salt Property

Melting point:: 168 °C (dec.)(lit.)
alpha: 33 º (c=3, water)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: H₂O: 0.5 M at 20 °C, clear, colorless to faintly yellow
form: Solid
pka: 1.9
color: White to Off-White
Water Solubility: soluble
InChIKey: YXHRQQJFKOHLAP-UROAIUCXNA-M
CAS DataBase Reference: 1180-95-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 37
Safety Statements: 24/25
WGK Germany: 3
F: 3-10
HS Code: 29242990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 580221
Product name: Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem
Purity: Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A
Packaging: 5G
Price: $211
Updated: 2025/07/31

Sigma-Aldrich

Product number: 580221
Product name: Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem
Purity: Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A
Packaging: 50g
Price: $807
Updated: 2025/07/31

Cayman Chemical

Product number: 15935
Product name: Taurodeoxycholic Acid (sodium salt)
Purity: ≥95%
Packaging: 1g
Price: $35
Updated: 2021/12/16

Cayman Chemical

Product number: 15935
Product name: Taurodeoxycholic Acid (sodium salt)
Purity: ≥95%
Packaging: 5g
Price: $88
Updated: 2021/12/16

Cayman Chemical

Product number: 15935
Product name: Taurodeoxycholic Acid (sodium salt)
Purity: ≥95%
Packaging: 25g
Price: $350
Updated: 2021/12/16

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Taurodeoxycholic acid sodium salt Chemical Properties,Usage,Production

Chemical Properties

white to almost white crystalline powder

Uses

Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

in vivo

Taurodeoxycholate (1.25-5 mg/kg, p.o., 6 days) sodium salt ameliorates dextran sodium sulfate (DSS)-induced colitis in mice^[9].
Taurodeoxycholate sodium salt (Taurodeoxycholic acid form, 50 mg/kg; i.p.; once daliy for 34 d) prevents neuropathology and associated behavioral deficits in the 3-nitropropionic acid rat model of Huntington's disease (HD) ^[10].
Taurodeoxycholate sodium salt (Taurodeoxycholic acid form, 500 mg/kg; s.c.; once every 3 d for 7 weeks) leads to a significant reduction in striatal neuropathology of the R6/2 transgenic HD mouse^[11].
Taurodeoxycholate (0.5 mg/kg; i.v., once) sodium salt confers protection to C57BL/6N mice with sepsis, but does not protect TGR5 KO mice under sepsis^[12].

Animal Model:	A mouse colitis model (fed with 3% (w/v) DSS in drinking water for the first seven days and then switched to normal drinking water for an additional two days)^[9]
Dosage:	1.25, 2.5, and 5 mg/kg
Administration:	Oral gavage (p.o.), from day 3 to day 8, once a day
Result:	Prevented loss of body weight, shortening of the colon, production of pro-inflammatory cytokines, infiltration of pro-inflammatory cells, and mucosal ulceration in the colon.

Animal Model:	Huntington's disease model in mouse^[10]
Dosage:	50 mg/kg
Administration:	Intraperitoneal injection; once daliy for 34 d, injected 3-NP at 6 hr after Taurodeoxycholic acid treatment
Result:	Reduced striatal atrophy, decreased striatal apoptosis, as well as fewer and smaller size ubiquitinated neuronal intranuclear huntingtin inclusions. Significantly improved locomotor and sensorimotor deficits.

Animal Model:	C57BL/6N mice, Lipopolysaccharides (HY-D1056) injection model of sepsis^[12]
Dosage:	0.5 mg/kg
Administration:	Intravenous injection, 30 min or 24 h after LPS injection
Result:	Improved the survival rate of mice with sepsis. Decreased liver and kidney damage in septic mice. Ameliorated systemic inflammation and normalized blood pressure in septic mice.

Purification Methods

The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]

Taurodeoxycholic acid sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Taurodeoxycholic acid sodium salt manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: Taurodeoxycholic acid sodium salt 1180-95-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97%min
Supply Ability: 2000KGS
Release date: 2025-08-16

Anhuyan (Hainan) Biotechnology Co., LTD

Product: Taurodeoxycholic acid sodium salt 1180-95-6
Price: US $2.00/g
Min. Order: 1g
Purity: 99.99
Supply Ability: 10000
Release date: 2025-06-05

Shaanxi Xianhe Biotech Co., Ltd

Product: Sodium taurodeoxycholate 1180-95-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 1000KG
Release date: 2025-04-22

1180-95-6, Taurodeoxycholic acid sodium saltRelated Search:

Taurine 2-aminoethanesulphonamide monohydrochloride GLYCOCHOLIC ACID SODIUM SALT Tauroursodeoxycholate Sodium deoxycholate TAUROCHOLIC ACID SODIUM SALT HYDRATE Tauroursodeoxycholic acid TAUROURSODEOXYCHOLIC ACID SODIUM SALT TAUROCHENODEOXYCHOLIC ACID SODIUM SALT Sodium taurodeoxycholate hydrate TAUROHYODEOXYCHOLIC ACID SODIUM SALT Sodium taurocholate taurohyodeoxycholic acid Taurohyodeoxycholic acid sodium salt hydrate Taurodeoxycholic acid sodium salt SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Sodium cholate Sodium tauroglycocholate

TAURODEOXYCHOLIC ACID SODIUM

TAURODEOXYCHOLIC ACID SODIUM SALT

Taurodeoxycholic acid sodium salt hydrate

SODIUM TAURODEOXYCHOLATE

SODIUM TAURODEOXYCHOLATE SODIUM SALT

SODIUM TAURODESOXYCHOLATE SODIUM SALT

2-[(3ALPHA,12ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)-AMINO] ETHANESULFONIC ACID SODIUM SALT

5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL 24-N-(2-SULFOETHYL)-AMIDE SODIUM

5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT

3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT

sodium 2-[[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate

Ethanesulfonic acid, 2-(3.alpha.,5.beta.,12.alpha.)-3,12-dihydroxy-24-oxocholan-24-ylamino-, monosodium salt

sodium taurodeoxylate

Ursodeoxycholic Impurity 16

sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate

Sodium 2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate

Cholane, ethanesulfonic acid deriv.

Sodium deoxytaurocholate

Sodium taurodesoxycholate

Taurodeoxycholate sodium

Taurodeoxycholic acid sodium salt hydrate,97%

2-[(3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid sodium salt

2-[(3α,12α-Dihydroxy-24-oxo-5β-cholane)-24-ylamino]ethanesulfonic acid sodium salt

3α,12α-Dihydroxy-24-[[2-(sodiooxysulfonyl)ethyl]amino]-5β-cholane-24-one

N-(3α,12α-Dihydroxy-24-oxo-5β-cholane-24-yl)taurine sodium salt

N-[2-(Sodiooxysulfonyl)ethyl]-3α,12α-dihydroxy-5β-cholane-24-oic amide

Sodium tarurodeoxycholate

2-(3α,6α-Dihydroxy-24-oxo-5β-cholan-24-ylamino)ethanesulfonic acid sodium salt

Sodium Taurodeoxycholic acid

Taurodeoxycholic acid sodium salt ,97%

Taurodeoxychloic Acid SodiuM Salt

SodiuM taurodeoxycholat

N-(3α,12α-Dihydroxy-5β-cholan-24-oyl)-taurine MonosodiuM Salt

SodiuM 3α,12α-Dihydroxy-5β-cholanoyltaurate

SODIUM TAUROUSODEOXYCHOLATE

Taurodeoxycholate sodium salt

Ethanesulfonic Acid,2-[[(3A,5B,12A-3,12-Dihydroxy-24-OxocholaN-24-Yl]Amino]-, Monosodium Salt

Sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate

Taurodeoxycholic acid sodium saltr

Taurodeoxycholic acid sodium salt ISO 9001：2015 REACH

Taurodeoxycholicacid (Crude)

sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-o...

Sodium taurodeoxycholate, hydrate, ≥95% (HPLC)

)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate

12B1

5B2

sodium 2-[[(3B1

Sodium Taurodeoxycholate Dried (STDC Dried) extrapure, 97%

Urosodeoxycholic Acid Impurity 16

5β-CHOLANIC ACID-3α, 12α-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT

Sodium taurine deoxycholate

Taurodeoxycholate sodium salt, 10 mM in DMSO

Taurodeoxycholic Acid Sodium Salt (Sodium Taurodeoxycholate)

TAURODEOXYCHOLIC ACID SODIUM SALT-2,2,4,4-d4 ACID

1180-95-6

C26H44NNaO6SxH2O

C26H44NO6S種a

Anionic