D(+)-Malic acid

ChemicalBook > CAS DataBase List > D(+)-Malic acid

Product Name: D(+)-Malic acid
CAS No.: 636-61-3
Chemical Name: D(+)-Malic acid
Synonyms: D-MALIC ACID;(R)-MALIC ACID;D-(+)-MALIC ACID;(2R)-2-Hydroxybutanedioic acid;D-(+)-MaL;D(+)-Malic;D-APPLE ACID;(R)-malicaci;l(+)-malicaci;D-Aepfelsaeure
CBNumber: CB9373789
Molecular Formula: C4H6O5
Formula Weight: 134.09
MOL File: 636-61-3.mol

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D(+)-Malic acid Property

Melting point:: 98-102 °C (lit.)
alpha: 2.2 º (c=3, H2O)
Boiling point:: 167.16°C (rough estimate)
Density: 1.60
refractive index: 6.5 ° (C=10, Acetone)
storage temp.: Store below +30°C.
solubility: Soluble in methanol, ethanol, acetone, ether.
form: Crystalline Powder
pka: 3.61±0.23(Predicted)
color: White
PH: 2.2 (10g/l, H2O, 20℃)
optical activity: [α]20/D +28.0±2°, c = 5.5% in pyridine
Water Solubility: soluble
Merck: 14,5707
BRN: 1723540
LogP: -1.370 (est)
CAS DataBase Reference: 636-61-3(CAS DataBase Reference)
NIST Chemistry Reference: (r)-Hydroxybutanedioic acid(636-61-3)

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41-36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: ON7260000
HS Code: 29181980

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 02300
Product name: D-(+)-Malic acid
Purity: unnatural form, ≥97.0% (T)
Packaging: 1g
Price: $34.02
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.00763
Product name: D-(+)-Malic acid
Purity: for the resolution of racemates for synthesis
Packaging: 5G
Price: $120
Updated: 2024/03/01

Sigma-Aldrich

Product number: 46940-U
Product name: D-Malic acid
Purity: analytical standard
Packaging: 1kit
Price: $37
Updated: 2024/03/01

Sigma-Aldrich

Product number: 02300
Product name: D-(+)-Malic acid
Purity: unnatural form, ≥97.0% (T)
Packaging: 5g
Price: $83.3
Updated: 2024/03/01

TCI Chemical

Product number: M0021
Product name: D-(+)-Malic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $21
Updated: 2024/03/01

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D(+)-Malic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece

Uses

D-(+)-Malic acid used as an acidulant and flavoring agent, food additive. And it is also used in the place of the less sour citric acid in sour sweets.

Uses

D-(+)-Malic acid can be used:

As a starting material for the enantioselective total synthesis of (?)-erinapyrone B.
As a chiral organocatalyst in the synthesis of α-aminophosphonates from various aldehydes, aniline, and diethyl phosphite.

Definition

ChEBI: An optically active form of malic acid having (R)-configuration.

Biological Activity

D-(+)-Malic acid, an active isomer of Malic acid, is a competitive inhibitor of L(--)malic acid transport.

Synthesis

Malic acid is isolated from immature apples; industrially prepared is obtained by catalytic oxidation of benzene, then reacting with water at high temperature and high pressure to generate maleic anhydride.

in vitro

Some bacteria belonging to Arthrobacter, Brevibacterium, Corynebacterium, Pseudomonas, Bacillus, and Acinetobacter produced D-(+)-Malic acid (D-Malic acid) from Maleic acid when the cells grown in a medium containing citraconic acid are reacted aerobically with Maleic acid in the pH 7.0 phosphate buffer containing 0.1% sodium chloride.

D(+)-Malic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-(-)-3-Pyrrolidinol hydrochloride (S)-(+)-3-Quinuclidinol (R)-3-Hydroxypyrrolidine (R)-(+)-1-Benzyl-3-pyrrolidinol

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View Lastest Price from D(+)-Malic acid manufacturers

Speranza Chemical Co., Ltd.

Product: D( )Malic acid 636-61-3
Price: US $0.00-0.00/KG
Min. Order: 5KG
Purity: 99%
Supply Ability: 500kg
Release date: 2023-11-29

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: D(+)-Malic acid 636-61-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-03-28

Hebei Duling International Trade Co. LTD

Product: D(+)-Malic acid 636-61-3
Price: US $56.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 tons
Release date: 2023-03-29

636-61-3, D(+)-Malic acidRelated Search:

Folic acid D(-)-Tartaric acid Disodium succinate L-Malic acid meso-2,3-Dibromosuccinic acid Succimer Hyaluronic acid ZINC ZIRCONATE Ethyl 2-(Chlorosulfonyl)acetate Diethyl succinosuccinate Malic acid Succinic acid Citric acid DL-Malic acid D(+)-Trehalose dihydrate 4-Hydroxy-D-(-)-2-phenylglycine Oxobutanedioic acid 3,4-dihydroxybutanoic acid

Butanedioic acid, hydroxy-, (R)-

hydroxy-,(R)-Butanedioicacid

l(+)-malicaci

(R)-(+)-MALIC ACID

(R)-MALIC ACID

Malic Acid Impurity 3

(2R)-2-hydroxybutanedioate

(+)-D-MALIC ACID

D-(+)-MALIC ACID

D-MALIC ACID

D-(+)-APPLE ACID

D-APPLE ACID

MALIC ACID, D-(+)-

(r)-hydroxybutanedioic acid

(R)-(+)-HYDROXYSUCCINIC ACID

(R)-HYDROXYSUCCINIC ACID

(R)-2-HYDROXY-SUCCINIC ACID

R(+)-2-HYDROXYSUCCINIC ACID

(R)-2-HYDROXYBUTANEDICARBOXYLIC ACID

D-MALIC ACID 100MG NEAT

D-(+)-MALIC ACID 99%

D-(+)-Malic acid, 98+%

D-Aepfelsaeure

D(+)-Malic

Butanedioic acid, hydroxy-, (2R)-

MALIC ACID, D-(+)-(P)

D-MALIC ACID / (R)-(+)-HYDROXYSUCCINIC ACID

D-HYDROXYBUTANEDIOIC ACID

D-HYDROXYSUCCINIC ACID

D-(+)-Malic acid ,99%

D-(+)-Malic acid,(R)-(+)-2-Hydroxysuccinic acid, D-Hydroxybutanedioic acid

D-(+)-MALIC ACID FOR THE RESOLUTION OF R

(R)-(+)-2-Hydroxysuccinic acid, D-(+)-Malic acid, D-Hydroxybutanedioic acid

(R)-(+)-2-Hydroxysuccinic acid, D-Hydroxybutanedioic acid

(2R)-2-Hydroxybutanedioic acid

(2R)-Malic acid

D-(+)-2-Hydroxysuccinic acid

[R,(+)]-2-Hydroxybutanedioic acid

D-(+)-Malic acid unnatural forM, >=97.0% (T)

D-(+)-Malic Acid, 97+%

Butanedioic acid, 2-hydroxy-, (2R)-

D-(+)-MalicAcid&gt

D-(+)-MaL

(R)-malicaci

dextro-malic acid

(+)-Malic acid

636-61-3

480-40-4

Asymmetric Synthesis

Optical Resolution

Chiral Building Blocks

Carboxylic Acids (Chiral)

for Resolution of Bases

Chiral Resolution Reagents

Chiral Resolving Reagents

Chiral Compound

Aliphatics

Chiral Reagents