MAFP

Product Name: MAFP
CAS No.: 188404-10-6
Chemical Name: MAFP
Synonyms: MAPF;MAFP;Phosphonofluoridicacid;METHYL ARACHIDONYL FLUOROPHOSPHONATE;Methyl arachidonyl fluorophosphonate, 98%,;(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenylmethylester;METHYLPHOSPHONOFLUORIDIC ACID 5,8,11,14-EICOSATETRAENYL ESTER;5Z,8Z,11Z,14Z-EICOSATETRAENYL-PHOSPHONOFLUORIDIC ACID, METHYL ESTER;Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester;(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester
CBNumber: CB9395022
Molecular Formula: C21H36FO2P
Formula Weight: 370.48
MOL File: 188404-10-6.mol

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MAFP Property

Boiling point:: 455.3±34.0 °C(Predicted)
Density: 0.960±0.06 g/cm3(Predicted)
RTECS: TA8108000
Flash point:: -16 °C
storage temp.: -70°C
solubility: DMF: 3 mg/ml; DMSO: 3 mg/ml; Ethanol: 3.5 mg/ml; Ethanol:PBS (pH 7.2) 1:1: .5 mg/ml; PBS (7.2): <1 mg/ml (colloidal suspension
form: methyl acetate solution
color: Light yellow to yellow
Sensitive: Air Sensitive

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Safety

Hazard Codes: F,Xi
Risk Statements: 11-36-66-67
Safety Statements: 16-26-29-33
RIDADR: UN 1231 3/PG 2
WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M2939
Product name: Methyl arachidonyl fluorophosphonate
Purity: ≥98%, methyl acetate solution (10 mg/mL)
Packaging: 5MG
Price: $241
Updated: 2023/06/20

Alfa Aesar

Product number: J67139
Product name: Methyl arachidonyl fluorophosphonate, 98%
Packaging: 5mg
Price: $173
Updated: 2021/12/16

Cayman Chemical

Product number: 70660
Product name: Methyl Arachidonyl Fluorophosphonate
Purity: ≥98%
Packaging: 1mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 70660
Product name: Methyl Arachidonyl Fluorophosphonate
Purity: ≥98%
Packaging: 5mg
Price: $119
Updated: 2024/03/01

Cayman Chemical

Product number: 70660
Product name: Methyl Arachidonyl Fluorophosphonate
Purity: ≥98%
Packaging: 10mg
Price: $220
Updated: 2024/03/01

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MAFP Chemical Properties,Usage,Production

Uses

(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester, is a cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors.

Definition

ChEBI: Methyl Arachidonyl Fluorophosphonate is a phosphonic ester.

Biological Activity

Potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH, anandamide amidase), the enzyme responsible for anandamide hydrolysis (IC 50 = 2.5 nM). Also binds irreversibly to CB 1 receptors (IC 50 = 20 nM).

Biochem/physiol Actions

MAFP is a selective, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic phospholipase A2, but not secretory phospholipase A2. MAFP is also a potent acetylcholinesterase inhibitor.

MAFP Preparation Products And Raw materials

Raw materials

Preparation Products

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MAFP Suppliers

China 24 Germany 3 India 1 Japan 1 Switzerland 2 United Kingdom 2 United States 10 Global 43

J & K SCIENTIFIC LTD.

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Sigma-Aldrich

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188404-10-6, MAFPRelated Search:

Citicoline sodium U-73343 Phosphatidylinositol (Soy) SodiuM 2-Heptadecanone D609 PACOCF3 ARISTOLOCHIC ACID SODIUM SALT ISOTETRANDRINE 7,7-DIMETHYLEICOSADIENOIC ACID 2-(P-AMYLCINNAMOYL)AMINO-4-CHLOROBENZOIC ACID 7-hydroxycoumarinyl-γ-Linolenate MANOALIDE OLEYLOXYETHYL PHOSPHORYLCHOLINE BROMOENOL LACTONE Thioetheramide PC UMBELLIFERYL ARACHIDONATE LUFFARIELLOLIDE MAFP

5Z,8Z,11Z,14Z-EICOSATETRAENYL-PHOSPHONOFLUORIDIC ACID, METHYL ESTER

(5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENYL-METHYL ESTER PHOSPHONOFLUORIDIC ACID

MAFP

MAPF

METHYL-5Z,8Z,11Z,14Z-EICOSATETRAENYL ESTER PHOSPHONOFLUORIDIC ACID METHYL ACETATE

METHYL ARACHIDONYL FLUOROPHOSPHONATE

METHYLPHOSPHONOFLUORIDIC ACID 5,8,11,14-EICOSATETRAENYL ESTER

(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenylmethylester

Phosphonofluoridicacid

MAPF, Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester

Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester

(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester

(5Z,8Z,11Z,14Z)-1-[fluoro(methoxy)phosphoryl]icosa-5,8,11,14-tetraene

Phosphonofluoridic acid, P-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-, methyl ester

Methyl arachidonyl fluorophosphonate, 98%,

Methyl Arachidonyl Fluorophosphonate, irreversible cPLA2 and iPLA2 inhibitor

188404-10-6

C21H36FO2P

BioChemical

Biochemicals and Reagents

Phospholipase A 2

P to Q

Enzyme Inhibitors

Enzyme Inhibitors by Enzyme

Enzymes, Inhibitors, and Substrates

Cannabinoid receptor

Fatty Acid Derivatives & Lipids, inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals