MAFP

Product Name: MAFP
CAS No.: 188404-10-6
Chemical Name: MAFP
Synonyms: MAPF;MAFP;Phosphonofluoridicacid;METHYL ARACHIDONYL FLUOROPHOSPHONATE;Methyl arachidonyl fluorophosphonate, 98%,;(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenylmethylester;METHYLPHOSPHONOFLUORIDIC ACID 5,8,11,14-EICOSATETRAENYL ESTER;5Z,8Z,11Z,14Z-EICOSATETRAENYL-PHOSPHONOFLUORIDIC ACID, METHYL ESTER;Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester;(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester
CBNumber: CB9395022
Molecular Formula: C21H36FO2P
Formula Weight: 370.48
MOL File: 188404-10-6.mol

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MAFP Property

Boiling point:: 455.3±34.0 °C(Predicted)
Density: 0.960±0.06 g/cm3(Predicted)
RTECS: TA8108000
Flash point:: -16 °C
storage temp.: -70°C
solubility: DMF: 3 mg/ml; DMSO: 3 mg/ml; Ethanol: 3.5 mg/ml; Ethanol:PBS (pH 7.2) 1:1: .5 mg/ml; PBS (7.2): <1 mg/ml (colloidal suspension
form: methyl acetate solution
color: Light yellow to yellow
Sensitive: Air Sensitive

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Safety

Hazard Codes: F,Xi
Risk Statements: 11-36-66-67
Safety Statements: 16-26-29-33
RIDADR: UN 1231 3/PG 2
WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M2939
Product name: Methyl arachidonyl fluorophosphonate
Purity: ≥98%, methyl acetate solution (10 mg/mL)
Packaging: 5MG
Price: $241
Updated: 2023/06/20

Alfa Aesar

Product number: J67139
Product name: Methyl arachidonyl fluorophosphonate, 98%
Packaging: 5mg
Price: $173
Updated: 2021/12/16

Cayman Chemical

Product number: 70660
Product name: Methyl Arachidonyl Fluorophosphonate
Purity: ≥98%
Packaging: 1mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 70660
Product name: Methyl Arachidonyl Fluorophosphonate
Purity: ≥98%
Packaging: 5mg
Price: $119
Updated: 2024/03/01

Cayman Chemical

Product number: 70660
Product name: Methyl Arachidonyl Fluorophosphonate
Purity: ≥98%
Packaging: 10mg
Price: $220
Updated: 2024/03/01

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MAFP Chemical Properties,Usage,Production

Uses

(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester, is a cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors.

Definition

ChEBI: Methyl Arachidonyl Fluorophosphonate is a phosphonic ester.

Biological Activity

Potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH, anandamide amidase), the enzyme responsible for anandamide hydrolysis (IC 50 = 2.5 nM). Also binds irreversibly to CB 1 receptors (IC 50 = 20 nM).

Biochem/physiol Actions

MAFP is a selective, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic phospholipase A2, but not secretory phospholipase A2. MAFP is also a potent acetylcholinesterase inhibitor.

MAFP Preparation Products And Raw materials

Raw materials

Preparation Products

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MAFP Suppliers

China 24 Germany 3 India 1 Japan 1 Switzerland 2 United Kingdom 2 United States 10 Global 43

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 5931
Advantage: 55

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29785
Advantage: 68

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
Advantage: 58

188404-10-6, MAFPRelated Search:

Citicoline sodium U-73343 Phosphatidylinositol (Soy) SodiuM 2-Heptadecanone D609 PACOCF3 ARISTOLOCHIC ACID SODIUM SALT ISOTETRANDRINE 7,7-DIMETHYLEICOSADIENOIC ACID 2-(P-AMYLCINNAMOYL)AMINO-4-CHLOROBENZOIC ACID 7-hydroxycoumarinyl-γ-Linolenate MANOALIDE OLEYLOXYETHYL PHOSPHORYLCHOLINE BROMOENOL LACTONE Thioetheramide PC UMBELLIFERYL ARACHIDONATE LUFFARIELLOLIDE MAFP

5Z,8Z,11Z,14Z-EICOSATETRAENYL-PHOSPHONOFLUORIDIC ACID, METHYL ESTER

(5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENYL-METHYL ESTER PHOSPHONOFLUORIDIC ACID

MAFP

MAPF

METHYL-5Z,8Z,11Z,14Z-EICOSATETRAENYL ESTER PHOSPHONOFLUORIDIC ACID METHYL ACETATE

METHYL ARACHIDONYL FLUOROPHOSPHONATE

METHYLPHOSPHONOFLUORIDIC ACID 5,8,11,14-EICOSATETRAENYL ESTER

(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenylmethylester

Phosphonofluoridicacid

MAPF, Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester

Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester

(all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester

(5Z,8Z,11Z,14Z)-1-[fluoro(methoxy)phosphoryl]icosa-5,8,11,14-tetraene

Phosphonofluoridic acid, P-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-, methyl ester

Methyl arachidonyl fluorophosphonate, 98%,

Methyl Arachidonyl Fluorophosphonate, irreversible cPLA2 and iPLA2 inhibitor

188404-10-6

C21H36FO2P

BioChemical

Biochemicals and Reagents

Phospholipase A 2

P to Q

Enzyme Inhibitors

Enzyme Inhibitors by Enzyme

Enzymes, Inhibitors, and Substrates

Cannabinoid receptor

Fatty Acid Derivatives & Lipids, inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals