ChemicalBook > CAS DataBase List > Mandelic acid

Mandelic acid

Product Name
Mandelic acid
CAS No.
611-71-2
Chemical Name
Mandelic acid
Synonyms
D-MANDELIC ACID;(R)-(-)-MANDELIC ACID;(R)-2-HYDROXY-2-PHENYLACETIC ACID;(R)-MANDELIC ACID;2-Hydroxy-2-phenylacetic acid;(R)-(-)-2-MANDELIC ACID;D-(-)-MANDELIC ACID;(-)-D-MANDELIC ACID;D-ALPHA-HYDROXYPHENYLACETIC ACID;R-MDA
CBNumber
CB9411418
Molecular Formula
C8H8O3
Formula Weight
152.15
MOL File
611-71-2.mol
More
Less

Mandelic acid Property

Melting point:
131-133 °C(lit.)
alpha 
-150 º (c=2.5, H2O)
Boiling point:
214.6°C (rough estimate)
Density 
1.1677 (rough estimate)
bulk density
670kg/m3
refractive index 
-153.5 ° (C=1, H2O)
Flash point:
>190℃
storage temp. 
Store below +30°C.
solubility 
109.8g/l soluble
form 
Crystalline Powder, Crystals or Flakes
pka
3.37(at 25℃)
color 
White to slightly yellow-beige
PH
3.34(1 mM solution);2.75(10 mM solution);2.22(100 mM solution);
optical activity
[α]25/D 151°, c = 1 in ethanol
Water Solubility 
It is partly soluble in water, freely soluble in isopropyl and ethyl alcohol.
Sensitive 
Light Sensitive
BRN 
2691094
Stability:
Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents.
InChIKey
IWYDHOAUDWTVEP-SSDOTTSWSA-N
LogP
0.550 (est)
CAS DataBase Reference
611-71-2(CAS DataBase Reference)
EPA Substance Registry System
Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)- (611-71-2)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
41-36/37/38
Safety Statements 
22-24/25-36-26-39-37/39
WGK Germany 
1
Hazard Note 
Irritant/Light Sensitive
TSCA 
Yes
HS Code 
29181980
Toxicity
LD50 orally in Rabbit: 5000 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.06914
Product name
(R)-(-)-Mandelic acid
Purity
for resolution of racemates for synthesis
Packaging
25g
Price
$84.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.06914
Product name
(R)-(-)-Mandelic acid
Purity
for resolution of racemates for synthesis
Packaging
100g
Price
$163
Updated
2024/03/01
Sigma-Aldrich
Product number
154210
Product name
(R)-(?)-Mandelic acid
Purity
ReagentPlus , ≥99%
Packaging
5g
Price
$38.5
Updated
2024/03/01
Sigma-Aldrich
Product number
154210
Product name
(R)-(?)-Mandelic acid
Purity
ReagentPlus , ≥99%
Packaging
25g
Price
$109
Updated
2024/03/01
TCI Chemical
Product number
M0662
Product name
D-(-)-Mandelic Acid
Purity
>99.0%(GC)(T)
Packaging
25g
Price
$56
Updated
2024/03/01
More
Less

Mandelic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

(R)-(-)-Mandelic acid, is used as a antiseptic ingredient particularly against urinary tract infections.Mandelic acid and its derivatives are used to apply the dual activities as an antibacterial agent and as an antiaging agent. It is used as an intermediate for the synthesis of target molecules for other applications.

Uses

(R)-(?)-Mandelic acid can be used:

  • As a chiral acid in the separation of diastereomeric salts for the synthesis of chiral pyridoindole based building block.
  • In the study of chiral acid selectivity of poly(3,4-ethylenedioxythiophene) (PEDOT) based chiral conducting?polymers.

Uses

Antiseptic (urinary).

Definition

ChEBI: (R)-mandelic acid is the (R)-enantiomer of mandelic acid. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a (R)-mandelate. It is an enantiomer of a (S)-mandelic acid.

Synthesis Reference(s)

The Journal of Organic Chemistry, 33, p. 2565, 1968 DOI: 10.1021/jo01270a105
Synthetic Communications, 18, p. 2141, 1988 DOI: 10.1080/00397918808068285

General Description

(R)-(-)-Mandelic acid, a chiral resolving agent, is also used as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. It can be synthesized from (R,S)-mandelonitrile with high yield and enantioselectivity using nitrilase enzyme.

Flammability and Explosibility

Non flammable

Purification Methods

Purify the mandelic acids by recrystallisation from H2O, *C6H6 or CHCl3. [Roger J Chem Soc 2168 1932,Jamison & Turner J Chem Soc 611 1942.] They have solubilities in H2O of ca 11% at 25o. [Banks & Davies J Chem Soc 73 1938.] The S-benzylisothiuronium salts has m 180o (from H2O) and [] D 25 (+) and (-) 57o (c20, EtOH) [El Masri et al. Biochem J 68 199 1958]. [Beilstein 10 IV 564.]

Mandelic acid Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4R)-(9CI)
More
Less

Mandelic acid Suppliers

Americas 1 Australia 1 Belgium 1 Canada 2 China 612 Europe 5 France 1 Germany 11 India 33 Japan 6 Slovakia 1 South Korea 2 Switzerland 4 The Netherlands 1 Ukraine 2 United Kingdom 12 United States 62 Global 757
Bridge Organics
Tel
+1269-649-4200
Fax
+1269-649-0611
Email
ab@bridgeorganics.com
Country
United States
ProdList
162
Advantage
55
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
ALB Technology Limited
Tel
702-983-3769
Fax
702-983-3769
Email
sales@albtechnology.com
Country
United States
ProdList
2993
Advantage
55
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
CarboMer, Inc.
Tel
--
Fax
--
Email
sales@carbomer.com
Country
United States
ProdList
4026
Advantage
67
McKinley Resources Inc.
Tel
--
Fax
--
Email
info@mckinleyresources.com
Country
United States
ProdList
31
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Penta International Corporation
Tel
--
Fax
--
Email
lisaa@pentamfg.com
Country
United States
ProdList
5042
Advantage
58
Glentham Life Sciences Ltd
Tel
--
Fax
--
Email
info@glentham.com
Country
United States
ProdList
2026
Advantage
58
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Penta Manufacturing Company
Tel
--
Fax
--
Email
sales@pentamfg.com
Country
United States
ProdList
5076
Advantage
65
Chiral Management
Tel
--
Fax
--
Email
sales@chiralmanagement.com
Country
United States
ProdList
1332
Advantage
30
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Chemiplus Corporation
Tel
--
Fax
--
Email
okazaki@chemiplus.com
Country
United States
ProdList
3198
Advantage
38
Advanced Scientific Internatiional,LLC
Tel
--
Fax
--
Email
webmaster@adscientific.net
Country
United States
ProdList
133
Advantage
30
NetQem
Tel
--
Fax
--
Email
sales@netqem.us
Country
United States
ProdList
1641
Advantage
38
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
srlmarketing@dishnetdsl.net
Country
United States
ProdList
1905
Advantage
64
Acros Organics USA
Tel
--
Fax
--
Email
eveleth@fisherchem.com
Country
United States
ProdList
3846
Advantage
81
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
Sinova Inc.
Tel
--
Fax
--
Email
sales@sinovainc.com
Country
United States
ProdList
4009
Advantage
58
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
BOSCHE SCIENTIFIC, LLC
Tel
--
Fax
--
Email
Sales@BoscheSci.com
Country
United States
ProdList
6477
Advantage
55
Advanced Asymmetrics, Inc.
Tel
--
Fax
--
Email
sales@advancedasymmetrics.com
Country
United States
ProdList
521
Advantage
42
Dow Chemical Company
Tel
--
Fax
--
Email
dowcig@dow.com
Country
United States
ProdList
770
Advantage
90
Fisher Scientific
Tel
--
Fax
--
Email
sales@fishersci.com
Country
United States
ProdList
2337
Advantage
86
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
More
Less

View Lastest Price from Mandelic acid manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
Mandelic acid 611-71-2
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99
Supply Ability
20tons
Release date
2024-02-06
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Mandelic acid 611-71-2
Price
US $35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/Week
Release date
2024-05-07
Hebei Saisier Technology Co., LTD
Product
Mandelic acid 611-71-2
Price
US $6.00/KG
Min. Order
1KG
Purity
More than 99%
Supply Ability
2000KG/MONTH
Release date
2024-04-24

611-71-2, Mandelic acidRelated Search:

Citric acid PHENYL VALERATE Hyaluronic acid 4-Chloromandelic acid Ethyl 2-(Chlorosulfonyl)acetate Folic acid Glycolic acid CHLOROPHOSPHONAZO III Phenylboronic acid 5-Pyrazolecarboxylic acid Ascoric Acid (S)-(+)-Mandelic acid 2-Chloromandelic acid Benactyzine Flurenol-butyl 3-Quinuclidinyl benzilate (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid Acetic anhydride

  • (R)-(-)-2-MANDELIC ACID
  • (R)-2-HYDROXY-2-PHENYLACETIC ACID
  • (R)-(-)-AMYGDALIC ACID
  • (R)-ALPHA-HYDROXYPHENYLACETIC ACID
  • R-(-)-ALPHA-HYDROXYPHENYLACETIC ACID
  • (R)-(-)-MANDELIC ACID
  • (R)-MANDELIC ACID
  • D-ALPHA-HYDROXYPHENYLACETIC ACID
  • D-A-HYDROXYPHENYLACETIC ACID
  • D-2-HYDROXY-PHENYLACETIC ACID
  • D-(-)-AMYGDALIC ACID
  • D-AMYGDALIC ACID
  • D-PHENYLGLYCOLIC ACID
  • (-)-D-MANDELIC ACID
  • D-(-)-MANDELIC ACID
  • D-MANDELIC ACID
  • L-2-hydroxy-2-phenylacetic acid
  • D(-)-MANDELIC ACID FOR RESOLUTION &
  • (R)-(-)-MANDELIC ACID, 99+%
  • (R)-(-)-MANDELIC ACID, 98% (99% EE/GLC)
  • (R)-(-)-MANDELIC ACID 99%
  • D-(-)-α-Hydroxybenzeneacetic acid
  • ALPHAR-HYDROXY-BENZENEACETIC ACID
  • D-Mandelic acid or R-(-)Mandelic acid
  • Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)-
  • (r)-(-)-à-hydroxyphenylacetic acid
  • D-mandelic acid(R-mandelic acid)
  • (R)-alpha-Hydrophenylacetic acid
  • D-(-)-Mandelic acid 98%
  • L-2-Hydroxy-2-phenylessigsure
  • D-minus-mandelic acid sigma grade
  • [R,(-)]-α-Hydroxybenzeneacetic acid
  • D-()-Mandelic acid,(R)-α-Hydroxyphenylacetic acid
  • (R)-(-)-Mandelic acid, ChiPros\(tm, 99+% ee 99+%
  • )-Mandel
  • (R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-Hydroxy(phenyl)ethanoic acid, D-(-)-Phenylglycolic acid
  • (R)-Alfa-hydroxyphenylacetic acid
  • (R)-()-Mandel
  • (R)-(-)-Mandelic acid, 99% 25GR
  • (R)-(-)-Mandelic acid, 98% e.e.
  • (R)-(-)-MANDELIC ACID FOR RESOLUTION OF
  • (R)-2-Phenylglycolic acid
  • (R)-alpha-Hydroxy-benzeneacetic acid
  • Sertraline EP IMpurity E
  • (R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-2-Hydroxy-2-phenylethanoic acid, D-(-)-Phenylglycolic acid
  • (R)-(-)-Mandelic acid, ChiPros 99+%, ee 99+%
  • D-MANDELIC ACID extrapure
  • (2R)-2-Hydroxy-2-phenylacetic acid
  • (R)-a-Hydroxybenzeneacetic acid
  • (R)-a-Hydroxyphenylacetic acid
  • D-2-Phenylglycolic acid
  • (R)-(-)-MANDELIC ACID: CHIPROS 99%, EE 99%
  • 2-Hydroxy-2-phenylacetic acid
  • 2-Phenylglycolic acid
  • a-Hydroxy-benzeneacetic acid
  • alpha-Hydroxyphenylacetic acid
  • Hydroxy(phenyl)acetic acid
  • R-Mandelic acid D-Mandelic acid