ChemicalBook > CAS DataBase List > 4-PIPERAZIN-1-YL-PHENYLAMINE

4-PIPERAZIN-1-YL-PHENYLAMINE

Product Name
4-PIPERAZIN-1-YL-PHENYLAMINE
CAS No.
67455-41-8
Chemical Name
4-PIPERAZIN-1-YL-PHENYLAMINE
Synonyms
TIMTEC-BB SBB010619;4-PIPERAZINOANILINE;4-PIPERAZIN-1-YLANILINE;4-(1-Piperazinyl)aniline;4-(4-AMinophenyl)piperazine;4-PIPERAZIN-1-YL-PHENYLAMINE;4-(1-Piperazinyl)aniline, 97%;1-(4-AMINO-PHENYL)-PIPERAZINE;1-(4-AMinophenyl)piperazine 97%;BenzenaMine, 4-(1-piperazinyl)-
CBNumber
CB9452907
Molecular Formula
C10H15N3
Formula Weight
177.25
MOL File
67455-41-8.mol
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4-PIPERAZIN-1-YL-PHENYLAMINE Property

Melting point:
119-123 °C (lit.)
Boiling point:
380.2±27.0 °C(Predicted)
Density 
1.107±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
form 
Powder
pka
9.12±0.10(Predicted)
color 
White to purple
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Safety

Hazard Codes 
Xn
Risk Statements 
22-37/38-41
Safety Statements 
26-39
WGK Germany 
2
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
A615655
Product name
1-(4-Aminophenyl)piperazine
Packaging
50mg
Price
$60
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-1-WD
Product name
4-Piperazin-1-ylaniline
Purity
96%
Packaging
1g
Price
$96
Updated
2021/12/16
AK Scientific
Product number
0375AC
Product name
4-(Piperazin-1-yl)aniline
Packaging
1g
Price
$104
Updated
2021/12/16
Matrix Scientific
Product number
081179
Product name
1-(4-Aminophenyl)piperazine
Purity
97%
Packaging
1g
Price
$147
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-1-WD
Product name
4-Piperazin-1-ylaniline
Purity
96%
Packaging
5G
Price
$288
Updated
2021/12/16
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4-PIPERAZIN-1-YL-PHENYLAMINE Chemical Properties,Usage,Production

Uses

4-Piperazinoaniline(CAS#67455-41-8)is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.

Synthesis

6269-89-2

67455-41-8

General procedure for the synthesis of 1-(4-aminophenyl)piperazine from 1-(4-nitrophenyl)piperazine: 1-(4-nitrophenyl)piperazine (414 mg, 2 mmol) was dissolved in a mixed solvent of ethanol (15 mL) and tetrahydrofuran (15 mL), and 10% palladium/carbon catalyst (50 mg) was added. The reaction was stirred for 3 h at room temperature under hydrogen atmosphere. The progress of the reaction was monitored by thin layer chromatography (TLC) during the reaction. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad to remove the catalyst. The filtrate was concentrated under reduced pressure to afford the target product 1-(4-aminophenyl)piperazine (319 mg, 90.0% yield).

References

[1] Synthetic Communications, 2012, vol. 42, # 2, p. 213 - 222
[2] RSC Advances, 2015, vol. 5, # 113, p. 93433 - 93437
[3] Green Chemistry, 2017, vol. 19, # 14, p. 3400 - 3407
[4] Tetrahedron Letters, 1999, vol. 40, # 31, p. 5655 - 5659
[5] Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2011, vol. 41, # 1, p. 114 - 119

4-PIPERAZIN-1-YL-PHENYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-PIPERAZIN-1-YL-PHENYLAMINE Suppliers

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View Lastest Price from 4-PIPERAZIN-1-YL-PHENYLAMINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1-(4-Aminophenyl)piperazine 67455-41-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

67455-41-8, 4-PIPERAZIN-1-YL-PHENYLAMINERelated Search:

1-METHYL-4-(4-NITROPHENYL)PIPERAZINE 1-(4-Nitrophenyl)piperazine 4-(4-Methylpiperazino)aniline 2-PIPERAZIN-1-YL-PHENYLAMINE 3-(4-Methylpiperazin-1-yl)aniline 3-CHLORO-4-(4-METHYL-PIPERAZIN-1-YL)-PHENYLAMINE 3-Fluoro-4-(4-methylpiperazin-1-yl)aniline 2-(4-METHYL-PIPERAZIN-1-YL)-PHENYLAMINE 4-[4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYLAMINE 4-(4-ETHYL-PIPERAZIN-1-YL)-PHENYLAMINE BUTTPARK 83\09-70 N-[4-(4-METHYLPIPERAZINO)PHENYL]PENTANAMIDE 4-(4-BENZYL-PIPERAZIN-1-YL)-PHENYLAMINE N-[4-(4-METHYLPIPERAZINO)PHENYL]ACETAMIDE 2,2-DIMETHYL-N-[4-(4-METHYLPIPERAZINO)PHENYL]PROPANAMIDE 2-(4-METHANESULFONYL-PIPERAZIN-1-YL)-PHENYLAMINE 3-PIPERAZIN-1-YL-PHENYLAMINE DOUBLE HYDROCHLORIDE 2,4-BIS-(4-METHYL-PIPERAZIN-1-YL)-PHENYLAMINE

  • 4-PIPERAZIN-1-YLANILINE
  • 4-(1-Piperazinyl)aniline, 97%
  • BenzenaMine, 4-(1-piperazinyl)-
  • 4-(4-AMinophenyl)piperazine
  • 1-(4-AMinophenyl)piperazine 97%
  • 1-(4-AMINO-PHENYL)-PIPERAZINE
  • 4-PIPERAZIN-1-YL-PHENYLAMINE
  • 4-PIPERAZINOANILINE
  • TIMTEC-BB SBB010619
  • Benzenamine, 4-(1-piperazinyl)- (9CI)
  • 4-PIPERAZIN-1-YL-PHENYLAMINE ISO 9001：2015 REACH
  • 4-(1-Piperazinyl)aniline
  • 67455-41-8
  • Building Blocks
  • Piperazines
  • Heterocyclic Building Blocks
  • PIPERIDINE
  • Building Blocks
  • C10
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • pharmacetical
  • Amines
  • Phenyls & Phenyl-Het
  • Phenyls & Phenyl-Het
  • Building Blocks
  • Heterocyclic Building Blocks
  • Piperazines